bosutinib
chemical compound
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Summary
bosutinib is a type of chemical entity[1].
Key Facts
- Physically interacts with: ABL proto-oncogene 1, non-receptor tyrosine kinase[2], Calcium/calmodulin dependent protein kinase ID[3], Calcium/calmodulin dependent protein kinase II gamma[4], FYN proto-oncogene, Src family tyrosine kinase[5], Fyn related Src family tyrosine kinase[6], LYN proto-oncogene, Src family tyrosine kinase[7], Mitogen-activated protein kinase kinase kinase kinase 5[8], Serine/threonine kinase 10[9], Serine/threonine kinase 24[10], Serine/threonine kinase 4[11], SRC proto-oncogene, non-receptor tyrosine kinase[12], TXK tyrosine kinase[13], Tyrosine kinase non receptor 2[14]
- Canonical SMILES: CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC[15]
- Chemical formula: C₂₆H₂₉Cl₂N₅O₃[16]
- Subclass of: chemical compound[17]
- Has use: medication[18]
- Significant drug interaction: voriconazole[19], erythromycin[20], clarithromycin[21], crizotinib[22], idelalisib[23]
- NCI Thesaurus ID: C60809[24]
- Mass: 529.165 dalton[25]
- Medical condition treated: leukemia[26]
- Subject has role: protein kinase inhibitors[27], xenobiotic-transporting ATPase inhibitor[28]
- Pregnancy category: US pregnancy category D[29]
- Active ingredient in: Bosulif[30]
- LiverTox likelihood score: LiverTox toxicity likelihood category D[31]