TXK tyrosine kinase

mammalian protein found in Homo sapiens

Protein protein Q21119231

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TXK tyrosine kinase

Summary

TXK tyrosine kinase is a protein^[1].

Key Facts

TXK tyrosine kinase's instance of is recorded as protein^[2].
TXK tyrosine kinase's physically interacts with is recorded as bosutinib^[3].
TXK tyrosine kinase is part of SH3-like domain superfamily^[4].
TXK tyrosine kinase is part of Protein kinase-like domain superfamily^[5].
TXK tyrosine kinase is part of SH2 domain superfamily^[6].
TXK tyrosine kinase is part of Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family^[7].
TXK tyrosine kinase is part of SH2 domain, protein family^[8].
TXK tyrosine kinase is part of Tyrosine-protein kinase TXK, SH3 domain, protein family^[9].
TXK tyrosine kinase is part of Tyrosine-protein kinase TXK, SH2 domain, protein family^[10].
TXK tyrosine kinase is part of SH3 domain, protein family^[11].
TXK tyrosine kinase is part of Protein kinase domain, protein family^[12].
TXK tyrosine kinase is part of Protein kinase, ATP binding site, protein family^[13].
TXK tyrosine kinase is part of Tyrosine-protein kinase, catalytic domain, protein family^[14].
TXK tyrosine kinase is part of Tyrosine-protein kinase, active site, protein family^[15].
TXK tyrosine kinase comprises tyrosine-protein kinase, active site^[16].
TXK tyrosine kinase comprises SH3 domain^[17].
TXK tyrosine kinase comprises protein kinase, ATP binding site^[18].
TXK tyrosine kinase comprises protein kinase domain^[19].
TXK tyrosine kinase comprises tyrosine-protein kinase, catalytic domain^[20].
TXK tyrosine kinase comprises SH2 domain^[21].
TXK tyrosine kinase comprises serine-threonine/tyrosine-protein kinase, catalytic domain^[22].
TXK tyrosine kinase comprises Tyrosine-protein kinase TXK, SH3 domain^[23].
TXK tyrosine kinase comprises Tyrosine-protein kinase TXK, SH2 domain^[24].
TXK tyrosine kinase's molecular function is recorded as transferase activity^[25].
TXK tyrosine kinase's molecular function is recorded as nucleotide binding^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of SH3-like domain superfamily, Protein kinase-like domain superfamily, SH2 domain superfamily, Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family, SH2 domain, protein family, Tyrosine-protein kinase TXK, SH3 domain, protein family, Tyrosine-protein kinase TXK, SH2 domain, protein family, SH3 domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Tyrosine-protein kinase, catalytic domain, protein family, Tyrosine-protein kinase, active site, protein family

Properties

Biological process cell differentiation, regulation of transcription, DNA-templated, adaptive immune response, phosphorylation, tissue regeneration, transmembrane receptor protein tyrosine kinase signaling pathway, immune system process, regulation of transcription by RNA polymerase II, cytokine production, positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of interferon-gamma production, activation of phospholipase C activity, transcription, DNA-templated, protein phosphorylation, regulation of cell population proliferation, peptidyl-tyrosine autophosphorylation, integrin-mediated signaling pathway, protein autophosphorylation, regulation of platelet activation, T cell receptor signaling pathway, positive regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, adaptive immune response, T cell receptor signaling pathway, protein phosphorylation

Cell component cytoplasm, membrane, extrinsic component of cytoplasmic side of plasma membrane, plasma membrane, nucleus

Ec enzyme number 2.7.10.2

Encoded by TXK

Found in taxon Homo sapiens

Has part(s) tyrosine-protein kinase, active site, SH3 domain, protein kinase, ATP binding site, protein kinase domain, tyrosine-protein kinase, catalytic domain, SH2 domain, serine-threonine/tyrosine-protein kinase, catalytic domain, Tyrosine-protein kinase TXK, SH3 domain, Tyrosine-protein kinase TXK, SH2 domain

Molecular function transferase activity, nucleotide binding, DNA binding, protein kinase activity, DNA-binding transcription activator activity, RNA polymerase II-specific, kinase activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, protein binding, protein tyrosine kinase activity, signaling receptor binding, ATP binding, non-membrane spanning protein tyrosine kinase activity, non-membrane spanning protein tyrosine kinase activity

Physically interacts with bosutinib

External References (4)

Ensembl protein id ENSP00000264316, ENSP00000422139, ENSP00000422798, ENSP00000423481, ENSP00000424070

Pdb structure id 2DM0

Refseq protein id NP_003319, XP_011512049, XP_011512050, XP_016864070, XP_016864071, XP_024309968

Uniprot protein id P42681

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ TXK tyrosine kinase — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ TXK tyrosine kinase — physically interacts with (P129): bosutinib. IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 2016-08-17. wikidata.org.
[4] ↑ TXK tyrosine kinase — part of (P361): SH3-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ TXK tyrosine kinase — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ TXK tyrosine kinase — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ TXK tyrosine kinase — part of (P361): Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[8] ↑ TXK tyrosine kinase — part of (P361): SH2 domain, protein family. wikidata.org.
[9] ↑ TXK tyrosine kinase — part of (P361): Tyrosine-protein kinase TXK, SH3 domain, protein family. wikidata.org.
[10] ↑ TXK tyrosine kinase — part of (P361): Tyrosine-protein kinase TXK, SH2 domain, protein family. wikidata.org.
[11] ↑ TXK tyrosine kinase — part of (P361): SH3 domain, protein family. wikidata.org.
[12] ↑ TXK tyrosine kinase — part of (P361): Protein kinase domain, protein family. wikidata.org.
[13] ↑ TXK tyrosine kinase — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[14] ↑ TXK tyrosine kinase — part of (P361): Tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[15] ↑ TXK tyrosine kinase — part of (P361): Tyrosine-protein kinase, active site, protein family. wikidata.org.
[16] ↑ TXK tyrosine kinase — has part(s) (P527): tyrosine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ TXK tyrosine kinase — has part(s) (P527): SH3 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ TXK tyrosine kinase — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ TXK tyrosine kinase — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ TXK tyrosine kinase — has part(s) (P527): tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ TXK tyrosine kinase — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ TXK tyrosine kinase — has part(s) (P527): serine-threonine/tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ TXK tyrosine kinase — has part(s) (P527): Tyrosine-protein kinase TXK, SH3 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ TXK tyrosine kinase — has part(s) (P527): Tyrosine-protein kinase TXK, SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ TXK tyrosine kinase — molecular function (P680): transferase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ TXK tyrosine kinase — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ TXK tyrosine kinase is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). TXK tyrosine kinase. Retrieved May 3, 2026, from https://4ort.xyz/entity/txk-tyrosine-kinase-q21119231

MLA

“TXK tyrosine kinase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/txk-tyrosine-kinase-q21119231.

BibTeX

@misc{4ortxyz_txk-tyrosine-kinase-q21119231_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{TXK tyrosine kinase}}, year = {2026}, url = {https://4ort.xyz/entity/txk-tyrosine-kinase-q21119231}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): TXK tyrosine kinase — https://4ort.xyz/entity/txk-tyrosine-kinase-q21119231 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/txk-tyrosine-kinase-q21119231 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

4w ago · Boghog · 2026-07-24 view diff on Wikidata ↗

Imported from → —

Encoded by → TXK

Wikidata description → mammalian protein found in Homo sapiens

Molecular function → transferase activity, nucleotide binding, DNA binding +10

+ 12 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.7.10.2, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"

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