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tucatinib

chemical compound
Class type of: chemical compound Q25100690

Facts

9 properties
Instance of
type of chemical entity
Subclass of
chemical compound
Has use
medication[6]
Canonical SMILES
CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5[4]
Chemical formula
C₂₆H₂₄N₈O₂[5]
Mass
+480.202[7]
Medical condition treated
breast cancer[8]
Physically interacts with
Erb-b2 receptor tyrosine kinase 2[3]
Subject has role
protein kinase inhibitors[9]
🏷️ Also known as
en ARRY-380 en ONT-380 en tucatinib ar توكاتينيب he טוקטיניב zh 图卡替尼
🔖 Identifiers · 20
CAS Registry Number
937263-43-9
ChEMBL ID
CHEMBL3989868
ChemSpider ID
34995558
DSSTox substance ID
DTXSID601027958
DrugBank ID
DB11652
DrugCentral ID
5389
Google Knowledge Graph ID
/g/11c32673_q
Guide to Pharmacology Ligand ID
9922
Human Metabolome Database ID
HMDB0304868
InChI
InChI=1S/C26H24N8O2/c1-16-10-17(5-7-22(16)36-19-8-9-34-23(12-19)28-15-30-34)31-24-20-11-18(4-6-21(20)27-14-29-24)32-25-33-26(2,3)13-35-25/h4-12,14-15H,13H2,1-3H3,(H,32,33)(H,27,29,31)
InChIKey
SDEAXTCZPQIFQM-UHFFFAOYSA-N
KEGG ID
D11141
Show all 20 identifiers +8
MedlinePlus drug identifier
a620032
Probes And Drugs ID
PD056028
PubChem CID
51039094
SureChEMBL ID
1193050
UK Parliament thesaurus ID
500748
UNII
234248D0HH
UniChem compound ID
29441242
WikiProjectMed ID
Tucatinib

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections
Has use 1
medication
Medical condition treated 1
breast cancer
Physically interacts with 1
Erb-b2 receptor tyrosine kinase 2
Subclass of 1
chemical compound
Subject has role 1
protein kinase inhibitors
← Drug or therapy used for treatment 1
breast cancer
← Physically interacts with 1
Erb-b2 receptor tyrosine kinase 2
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Summary

tucatinib is a type of chemical entity[1]. tucatinib is a type of chemical compound[2].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  2. [4] ↑ . PubChem. Retrieved . wikidata.org.
  3. [5] ↑ . PubChem. Retrieved . wikidata.org.
  4. [2] ↑ . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . PubChem. Retrieved . wikidata.org.
  7. [8] ↑ . wikidata.org.
  8. [9] ↑ . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). tucatinib. Retrieved November 3, 2026, from https://4ort.xyz/entity/tucatinib
MLA “tucatinib.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 Nov. 2026, https://4ort.xyz/entity/tucatinib.
BibTeX @misc{4ortxyz_tucatinib_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{tucatinib}}, year = {2026}, url = {https://4ort.xyz/entity/tucatinib}, note = {Accessed: 2026-11-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): tucatinib — https://4ort.xyz/entity/tucatinib (retrieved 2026-11-03)

Canonical URL: https://4ort.xyz/entity/tucatinib · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 19w ago · Nabbegat · 2026-06-19 view diff on Wikidata ↗
    Instance of → type of chemical entity
    Has use → medication
    Medical condition treated → breast cancer
    Subclass of → —
    + 6 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||tr */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/37300|batch #37300]]"
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