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TBX5

protein-coding gene in the species Homo sapiens
Class type of: protein-coding gene Q18031853

Facts

13 properties
Instance of
gene
Subclass of
protein-coding gene
Chromosome
human chromosome 12[12]
Cytogenetic location
12q24.21[15]
Encodes
T-box transcription factor 5[10]
Expressed in
tendon of biceps brachii, cardiac muscle tissue of right atrium, buccal mucosa cell, right auricle of heart, lower lobe of lung, right ventricle, myocardium of left ventricle, visceral pleura, right lung, oocyte[16][17][18][19][20][21][22][23][24][25]
Found in taxon
Homo sapiens[11]
Genetic association
Holt-Oram syndrome[13]
Genomic end
114408442, 114846247[6][7]
Genomic start
114791736, 114353911[4][5]
HomoloGene ID
160[3]
Ortholog
Tbx5, Tbx5, tbx5a[8][9]
Strand orientation
reverse strand[14]
🏷️ Also known as
en HOS en T-box 5 en T-box transcription factor 5 en TBX5
🔖 Identifiers · 11
Image (Wikimedia Commons)
Protein TBX5 PDB 2X6U.png ↗
Ensembl gene ID
ENSG00000089225
Ensembl transcript ID
ENST00000552726, ENST00000310346, ENST00000349716, ENST00000405440, ENST00000526441
Entrez Gene ID
6910
Exact match
identifiers.org
Freebase ID
/m/03gx3gx
HGNC ID
11604
HGNC gene symbol
TBX5
OMIM ID
601620
RefSeq RNA ID
NM_181486, NM_000192, NM_080717, NM_080718, XM_017019912
UMLS CUI
C1420615

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Summary

TBX5 is a gene[1]. TBX5 is a type of protein-coding gene[2].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . Ensembl Release 87. wikidata.org.
  2. [3] ↑ . NCBI Gene. Retrieved . wikidata.org.
  3. [4] ↑ . ensembl Release 106. wikidata.org.
  4. [5] ↑ . ensembl Release 106. wikidata.org.
  5. [6] ↑ . ensembl Release 106. wikidata.org.
  6. [7] ↑ . ensembl Release 106. wikidata.org.
  7. [8] ↑ . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  8. [9] ↑ . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  9. [10] ↑ . UniProt. Retrieved . wikidata.org.
  10. [11] ↑ . ensembl Release 106. wikidata.org.
  11. [12] ↑ . ensembl Release 106. wikidata.org.
  12. [13] ↑ . UniProt. Retrieved . search.clinicalgenome.org. Provenance: wikidata.org.
  13. [14] ↑ . ensembl Release 106. wikidata.org.
  14. [15] ↑ . NCBI Gene. Retrieved . wikidata.org.
  15. [16] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  16. [17] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  17. [18] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  18. [19] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  19. [20] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  20. [21] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  21. [22] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  22. [23] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  23. [24] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  24. [25] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). TBX5. Retrieved November 7, 2026, from https://4ort.xyz/entity/tbx5
MLA “TBX5.” 4ort.xyz Knowledge Graph, 4ort.xyz, 7 Nov. 2026, https://4ort.xyz/entity/tbx5.
BibTeX @misc{4ortxyz_tbx5_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{TBX5}}, year = {2026}, url = {https://4ort.xyz/entity/tbx5}, note = {Accessed: 2026-11-07}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 24w ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    HGNC gene symbol → TBX5
    Genetic association → Holt-Oram syndrome
    RefSeq RNA ID → NM_181486, NM_000192, NM_080717 +2
    Exact match → http://identifiers.org/ncbigene/6910
    + 24 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||gsw */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/32527|batch #32527]]: human gene name and description in Alemannic"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.