Proteasome subunit beta 11
mammalian protein found in Homo sapiens
Facts
10 properties- Instance of
- protein
- Part of
- Nucleophile aminohydrolases, N-terminal, Proteasome subunit beta type 11, Proteasome beta-type subunit, conserved site, protein family[4][5][6]
- Biological process
- proteolysis, proteolysis involved in cellular protein catabolic process, CD8-positive, alpha-beta T cell differentiation, protein deubiquitination, post-translational protein modification, proteasomal protein catabolic process, proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, MAPK cascade, protein polyubiquitination, stimulatory C-type lectin receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, regulation of cellular amino acid metabolic process, negative regulation of G2/M transition of mitotic cell cycle, anaphase-promoting complex-dependent catabolic process, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, tumor necrosis factor-mediated signaling pathway, NIK/NF-kappaB signaling, Fc-epsilon receptor signaling pathway, proteasome-mediated ubiquitin-dependent protein catabolic process, regulation of mRNA stability, T cell receptor signaling pathway, transmembrane transport, Wnt signaling pathway, planar cell polarity pathway, regulation of transcription from RNA polymerase II promoter in response to hypoxia, interleukin-1-mediated signaling pathway, negative regulation of canonical Wnt signaling pathway, positive regulation of canonical Wnt signaling pathway, regulation of mitotic cell cycle phase transition, regulation of hematopoietic stem cell differentiation[19][20][21][22][23][24][25][26][27][28][29][30][31][32]
- Cell component
- cytoplasm, cytosol, proteasome complex, nucleus, proteasome core complex, proteasome core complex, beta-subunit complex, nucleus, cytoplasm, proteasome core complex[13][14][15][16][17][18]
- EC enzyme number
- 3.4.25.1[8]
- Found in taxon
- Homo sapiens[34]
- Has part(s)
- Proteasome beta-type subunit, conserved site[7]
- Molecular function
- endopeptidase activity, peptidase activity, threonine-type endopeptidase activity, hydrolase activity, endopeptidase activity[9][10][11][12]
- Physically interacts with
- carfilzomib, ixazomib, Oprozomib[1][2][3]
🏷️ Also known as
en proteasome (prosome, macropain) subunit, beta type, 11
en Proteasome subunit beta 11
en proteasome subunit beta-5t
en proteasome subunit beta 5T
en proteasome subunit beta type-11
en PSMB11
🔖 Identifiers · 3
- Ensembl protein ID
- ENSP00000386212
- RefSeq protein ID
- NP_001093250
- UniProt protein ID
- A5LHX3
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