Proteasome subunit beta 1
mammalian protein found in Homo sapiens
Facts
11 properties- Instance of
- protein
- Part of
- Proteasome subunit beta 1, Nucleophile aminohydrolases, N-terminal, Proteasome beta-type subunit, conserved site, protein family[6][7][8]
- Biological process
- regulation of cellular amino acid metabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, regulation of mRNA stability, positive regulation of canonical Wnt signaling pathway, protein polyubiquitination, stimulatory C-type lectin receptor signaling pathway, tumor necrosis factor-mediated signaling pathway, MAPK cascade, proteolysis, Fc-epsilon receptor signaling pathway, NIK/NF-kappaB signaling, anaphase-promoting complex-dependent catabolic process, proteolysis involved in cellular protein catabolic process, T cell receptor signaling pathway, negative regulation of canonical Wnt signaling pathway, proteasome-mediated ubiquitin-dependent protein catabolic process, viral process, Wnt signaling pathway, planar cell polarity pathway, negative regulation of G2/M transition of mitotic cell cycle, protein deubiquitination, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, neutrophil degranulation, transmembrane transport, regulation of transcription from RNA polymerase II promoter in response to hypoxia, post-translational protein modification, regulation of hematopoietic stem cell differentiation, proteasomal protein catabolic process, proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, interleukin-1-mediated signaling pathway, regulation of mitotic cell cycle phase transition
- Cell component
- cytoplasm, cytosol, nucleoplasm, proteasome complex, extracellular exosome, nucleus, proteasome core complex, extracellular region, secretory granule lumen, ficolin-1-rich granule lumen, proteasome core complex, beta-subunit complex, nucleus, cytoplasm, proteasome core complex, extracellular exosome[16][17][18][19][20]
- Encoded by
- PSMB1
- Found in taxon
- Homo sapiens
- Has part(s)
- Proteasome beta-type subunit, conserved site[9]
- Imported from
- wholeness_audit_2026-05-02
- Molecular function
- endopeptidase activity, peptidase activity, protein binding, threonine-type endopeptidase activity, hydrolase activity, endopeptidase activity[10][11][12][13][14][15]
- Physically interacts with
- carfilzomib, ixazomib, Oprozomib[2][3][4]
🏷️ Also known as
en Macropain subunit C5
en Multicatalytic endopeptidase complex subunit C5
en Proteasome component C5
en Proteasome gamma chain
en Proteasome subunit beta 1
en PSMB1
🔖 Identifiers · 3
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Summary
Proteasome subunit beta 1 is a protein[1].