Proteasome 20S subunit alpha 7
mammalian protein found in Homo sapiens
Facts
11 properties- Instance of
- protein
- Part of
- Nucleophile aminohydrolases, N-terminal, Proteasome subunit alpha 7, Proteasome alpha-subunit, N-terminal domain, protein family[6][7][8]
- Biological process
- regulation of cellular amino acid metabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ubiquitin-dependent protein catabolic process, regulation of mRNA stability, positive regulation of canonical Wnt signaling pathway, protein polyubiquitination, stimulatory C-type lectin receptor signaling pathway, tumor necrosis factor-mediated signaling pathway, proteolysis, MAPK cascade, Fc-epsilon receptor signaling pathway, NIK/NF-kappaB signaling, anaphase-promoting complex-dependent catabolic process, proteolysis involved in cellular protein catabolic process, T cell receptor signaling pathway, negative regulation of canonical Wnt signaling pathway, proteasome-mediated ubiquitin-dependent protein catabolic process, viral process, Wnt signaling pathway, planar cell polarity pathway, negative regulation of G2/M transition of mitotic cell cycle, protein deubiquitination, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, transmembrane transport, regulation of transcription from RNA polymerase II promoter in response to hypoxia, post-translational protein modification, regulation of hematopoietic stem cell differentiation, proteasomal protein catabolic process, proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, interleukin-1-mediated signaling pathway, regulation of mitotic cell cycle phase transition
- Cell component
- cytoplasm, cytosol, nucleoplasm, proteasome complex, extracellular exosome, nucleus, proteasome core complex, postsynapse, proteasome core complex, alpha-subunit complex, nucleus, cytoplasm, proteasome core complex, proteasome core complex, alpha-subunit complex, extracellular exosome, postsynapse[17][18][19]
- Encoded by
- PSMA7
- Found in taxon
- Homo sapiens
- Has part(s)
- Proteasome alpha-subunit, N-terminal domain[9]
- Imported from
- wholeness_audit_2026-05-02
- Molecular function
- endopeptidase activity, peptidase activity, protein binding, identical protein binding, threonine-type endopeptidase activity, hydrolase activity, endopeptidase activity[10][11][12][13][14][15][16]
- Physically interacts with
- carfilzomib, ixazomib, Oprozomib[2][3][4]
🏷️ Also known as
en epididymis secretory protein Li 276
en Proteasome 20S subunit alpha 7
en proteasome (prosome, macropain) subunit, alpha type, 7
en proteasome subunit alpha 4
en proteasome subunit alpha 7
en proteasome subunit alpha type-7
en proteasome subunit RC6-1
en proteasome subunit XAPC7
en PSMA7
en testicular tissue protein Li 151
🔖 Identifiers · 4
- Ensembl protein ID
- ENSP00000359895, ENSP00000359898, ENSP00000359910, ENSP00000397047
- RefSeq protein ID
- NP_002783
- UniProt protein ID
- O14818
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Summary
Proteasome 20S subunit alpha 7 is a protein[1].