ponatinib

chemical compound
ChemicalSubstance type_of_chemical_entity Q198728
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ponatinib

Summary

ponatinib is a type of chemical entity[1]. ponatinib ranks in the top 6% of type_of_chemical_entity entities by monthly Wikipedia readership (40 views/month).[2]

Key Facts

  • ponatinib's instance of is recorded as type of chemical entity[3].
  • ponatinib's physically interacts with is recorded as ABL proto-oncogene 1, non-receptor tyrosine kinase[4].
  • ponatinib's physically interacts with is recorded as Cyclin dependent kinase 19[5].
  • ponatinib's physically interacts with is recorded as Cyclin dependent kinase 8[6].
  • ponatinib's physically interacts with is recorded as ret proto-oncogene[7].
  • ponatinib's physically interacts with is recorded as ABL proto-oncogene 1, non-receptor tyrosine kinase[8].
  • ponatinib's canonical SMILES is recorded as CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5[9].
  • ponatinib's chemical formula is recorded as C₂₉H₂₇F₃N₆O[10].
  • ponatinib is a type of unsaturated compound[11].
  • ponatinib is used for medication[12].
  • ponatinib's Commons category is recorded as Ponatinib[13].
  • ponatinib's mass is recorded as {'unit': 'Q483261', 'amount': '+532.22'}[14].
  • ponatinib's medical condition treated is recorded as acute myeloid leukemia[15].
  • ponatinib's medical condition treated is recorded as gastrointestinal stromal tumor[16].
  • ponatinib's World Health Organisation international non-proprietary name is recorded as {'lang': 'en', 'text': 'ponatinib'}[17].
  • ponatinib's subject has role is recorded as protein kinase inhibitors[18].
  • ponatinib's subject has role is recorded as antineoplastic[19].
  • ponatinib's subject has role is recorded as tyrosine-kinase inhibitor[20].
  • ponatinib's pregnancy category is recorded as US pregnancy category D[21].
  • ponatinib's active ingredient in is recorded as Iclusig[22].
  • ponatinib's stylized name is recorded as PONATinib[23].

Why It Matters

ponatinib ranks in the top 6% of type_of_chemical_entity entities by monthly Wikipedia readership (40 views/month).[2] ponatinib has Wikipedia articles in 10 language editions, a strong signal of global cultural recognition.[24] ponatinib is known by 5 alternative names across languages and contexts.[25]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . wikidata.org.
  2. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [5] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [6] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  5. [7] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  6. [8] . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  7. [9] . PubChem. Retrieved . wikidata.org.
  8. [10] . PubChem. Retrieved . wikidata.org.
  9. [11] . wikidata.org.
  10. [12] . wikidata.org.
  11. [13] . wikidata.org.
  12. [14] . PubChem. Retrieved . wikidata.org.
  13. [15] . Drug Indications Extracted from FAERS. Retrieved . wikidata.org.
  14. [16] . Drug Indications Extracted from FAERS. Retrieved . wikidata.org.
  15. [17] . ChEBI. Retrieved . wikidata.org.
  16. [18] . NDF-RT. Retrieved . wikidata.org.
  17. [19] . Medical Subject Headings. Retrieved . wikidata.org.
  18. [20] . wikidata.org.
  19. [21] . wikidata.org.
  20. [22] . RxNorm. Retrieved . wikidata.org.
  21. [23] . ismp.org. Retrieved . ismp.org. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [24] . Wikidata sitelinks. wikidata.org.
  3. [25] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). ponatinib. Retrieved May 3, 2026, from https://4ort.xyz/entity/ponatinib
MLA “ponatinib.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ponatinib.
BibTeX @misc{4ortxyz_ponatinib_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{ponatinib}}, year = {2026}, url = {https://4ort.xyz/entity/ponatinib}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): ponatinib — https://4ort.xyz/entity/ponatinib (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/ponatinib · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 4w ago · Nabbegat · 2026-06-19 view diff on Wikidata ↗
    Instance of type of chemical entity
    Has use medication
    Medical condition treated acute myeloid leukemia, gastrointestinal stromal tumor
    Subclass of
    + 8 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||tr */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/37300|batch #37300]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.