methotrexate

chemical compound
ChemicalSubstance type_of_chemical_entity Q422232
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methotrexate

Summary

methotrexate is a type of chemical entity[1]. methotrexate ranks in the top 1% of type_of_chemical_entity entities by monthly Wikipedia readership (1,191 views/month).[2]

Key Facts

  • methotrexate's instance of is recorded as type of chemical entity[3].
  • methotrexate's chemical structure is recorded as Methotrexate2DACS2.svg[4].
  • methotrexate's physically interacts with is recorded as solute carrier family 46 member 1[5].
  • methotrexate's physically interacts with is recorded as solute carrier family 19 member 1[6].
  • methotrexate's manufacturer is recorded as Pfizer[7].
  • methotrexate's GND ID is recorded as 4038985-6[8].
  • methotrexate's CAS Registry Number is recorded as 59-05-2[9].
  • methotrexate's EC number is recorded as 200-413-8[10].
  • methotrexate's canonical SMILES is recorded as CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O[11].
  • methotrexate's InChI is recorded as InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1[12].
  • methotrexate's InChIKey is recorded as FBOZXECLQNJBKD-ZDUSSCGKSA-N[13].
  • methotrexate's Library of Congress authority ID is recorded as sh85084418[14].
  • methotrexate's ATC code is recorded as L01BA01[15].
  • methotrexate's ATC code is recorded as L04AX03[16].
  • methotrexate's chemical formula is recorded as C₂₀H₂₂N₈O₅[17].
  • methotrexate's subclass of is recorded as Amethopterin[18].
  • methotrexate's part of is recorded as cellular response to methotrexate[19].
  • methotrexate's part of is recorded as methotrexate transmembrane transporter activity[20].
  • methotrexate's part of is recorded as response to methotrexate[21].
  • methotrexate's has use is recorded as medication[22].
  • methotrexate's Commons category is recorded as Methotrexate[23].
  • methotrexate's MeSH descriptor ID is recorded as D008727[24].
  • methotrexate's ChEMBL ID is recorded as CHEMBL34259[25].
  • methotrexate's Guide to Pharmacology Ligand ID is recorded as 4815[26].
  • methotrexate's Guide to Pharmacology Ligand ID is recorded as 4674[27].

Why It Matters

methotrexate ranks in the top 1% of type_of_chemical_entity entities by monthly Wikipedia readership (1,191 views/month).[2] methotrexate has Wikipedia articles in 25 language editions, a strong signal of global cultural recognition.[28] methotrexate is known by 34 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . wikidata.org.
  2. [4] . wikidata.org.
  3. [5] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [6] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  5. [7] . pfizer.com. pfizer.com. Provenance: wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . Global Substance Registration System. Retrieved . commonchemistry.cas.org. Provenance: wikidata.org.
  8. [10] . Global Substance Registration System. Retrieved . wikidata.org.
  9. [11] . PubChem. Retrieved . wikidata.org.
  10. [12] . PubChem. Retrieved . wikidata.org.
  11. [13] . PubChem. Retrieved . wikidata.org.
  12. [14] . Integrated Authority File. wikidata.org.
  13. [15] . DrugBank. wikidata.org.
  14. [16] . DrugBank. wikidata.org.
  15. [17] . PubChem. Retrieved . wikidata.org.
  16. [18] . wikidata.org.
  17. [19] . Gene Ontology release 2019-11-16. wikidata.org.
  18. [20] . Gene Ontology release 2019-11-16. wikidata.org.
  19. [21] . Gene Ontology release 2020-05-02. wikidata.org.
  20. [22] . wikidata.org.
  21. [23] . wikidata.org.
  22. [24] . wikidata.org.
  23. [25] . ChEMBL. Retrieved . wikidata.org.
  24. [26] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  25. [27] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). methotrexate. Retrieved May 3, 2026, from https://4ort.xyz/entity/methotrexate
MLA “methotrexate.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/methotrexate.
BibTeX @misc{4ortxyz_methotrexate_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{methotrexate}}, year = {2026}, url = {https://4ort.xyz/entity/methotrexate}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): methotrexate — https://4ort.xyz/entity/methotrexate (retrieved 2026-05-03)

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