Charcot–Marie–Tooth disease
neuromuscular disease that is characterized by a slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm
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Summary
Charcot–Marie–Tooth disease is a designated intractable/rare disease[1]. It draws 8,126 Wikipedia views per month (designated intractable rare disease category, ranking #38 of 201).[2]
Key Facts
- Instance of: rare disease[3], class of disease[4]
- Named after: Jean-Martin Charcot[5], Pierre Marie[6], Howard Henry Tooth[7]
- Subclass of: hereditary motor and sensory neuropathy[8], neuromuscular disease[9], monogenic disease[10], disease[11]
- Commons category: Charcot-Marie-Tooth disease[12]
- Symptoms and signs: muscle weakness[13], muscle atrophy[14], pes cavus[15], sensory loss[16], hyporeflexia[17], scoliosis[18]
- Has cause: mutation[19]
- Medical examination: genetic testing[20], neurological diagnostic techniques[21], electromyography[22]
- Possible treatment: unknown[23], physiotherapy[24]
- Prevalence: 0.0003[25]
- External data available at URL: http://www.nanbyou.or.jp/entry/3773[26]
- ICD-9-CM: 356.1[27]
- NCI Thesaurus ID: C75467[28]
- Health specialty: neurology[29]
- Genetic association: PMP22[30], GJB1[31], MPZ[32]
- Exact match: http://purl.obolibrary.org/obo/DOID_10595[33], http://identifiers.org/doid/DOID:10595[34]
- On focus list of Wikimedia project: WikiProject Medicine[35]
Why It Matters
Charcot–Marie–Tooth disease has Wikipedia articles in 21 language editions, a strong signal of global cultural recognition.[36] It is known by 92 alternative names across languages and contexts.[37]