allopurinol

medication to decrease high blood uric acid levels
ChemicalSubstance type_of_chemical_entity Q412486
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Summary

allopurinol is a type of chemical entity[1]. allopurinol ranks in the top 2% of type of chemical entity entities by monthly Wikipedia readership (6,033 views/month).[2]

Key Facts

  • Physically interacts with: Xanthine dehydrogenase[3]
  • Canonical SMILES: C1=C2C(=NC=NC2=O)NN1[4]
  • Chemical formula: C₅H₄N₄O[5]
  • Subclass of: chemical compound[6]
  • Has use: medication[7]
  • Commons category: Allopurinol[8]
  • Found in taxon: Rhodiola rosea[9], Schinus terebinthifolia[10], Gardenia oudiepe[11]
  • Significant drug interaction: mercaptopurine hydrate[12], azathioprine[13]
  • Mass: 136.038511 dalton[14]
  • Medical condition treated: gout attack[15], hyperuricemia[16], gout[17]
  • World Health Organisation international non-proprietary name: allopurinol[18]
  • Subject has role: enzyme inhibitor[19], antimetabolite[20], antigout agent[21], free radical scavengers[22], essential medicine[23], xanthine oxidase inhibitor[24]
  • Active ingredient in: Zyloprim[25], Aloprim[26]

Why It Matters

allopurinol has Wikipedia articles in 24 language editions, a strong signal of global cultural recognition.[27] allopurinol is known by 52 alternative names across languages and contexts.[28]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  2. [4] ↑ . PubChem. Retrieved . wikidata.org.
  3. [5] ↑ . PubChem. Retrieved . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . Identification of a novel UDP-glycosyltransferase gene from Rhodiola rosea and its expression during biotransformation of upstream precursors in callus culture. wikidata.org.
  8. [10] ↑ . Pentagalloylglucose, a xanthine oxidase inhibitor from a Paraguayan crude drug, "Molle-i" (Schinus terebinthifolius).. wikidata.org.
  9. [11] ↑ . Xanthine oxidase inhibitory activity of natural and hemisynthetic flavonoids from Gardenia oudiepe (Rubiaceae) in vitro and molecular docking studies.. wikidata.org.
  10. [12] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  11. [13] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  12. [14] ↑ . PubChem. Retrieved . wikidata.org.
  13. [15] ↑ . NDF-RT. Retrieved . wikidata.org.
  14. [16] ↑ . Drug Indications Extracted from FAERS. Retrieved . wikidata.org.
  15. [17] ↑ . Drug Indications Extracted from FAERS. Retrieved . wikidata.org.
  16. [18] ↑ . ChEMBL. Retrieved . wikidata.org.
  17. [19] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  18. [20] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  19. [21] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  20. [22] ↑ . Medical Subject Headings. Retrieved . wikidata.org.
  21. [23] ↑ . wikidata.org.
  22. [24] ↑ . wikidata.org.
  23. [25] ↑ . RxNorm. Retrieved . wikidata.org.
  24. [26] ↑ . RxNorm. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [27] ↑ . Wikidata sitelinks. wikidata.org.
  3. [28] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). allopurinol. Retrieved October 16, 2026, from https://4ort.xyz/entity/allopurinol
MLA “allopurinol.” 4ort.xyz Knowledge Graph, 4ort.xyz, 16 Oct. 2026, https://4ort.xyz/entity/allopurinol.
BibTeX @misc{4ortxyz_allopurinol_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{allopurinol}}, year = {2026}, url = {https://4ort.xyz/entity/allopurinol}, note = {Accessed: 2026-10-16}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): allopurinol — https://4ort.xyz/entity/allopurinol (retrieved 2026-10-16)

Canonical URL: https://4ort.xyz/entity/allopurinol · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 4d ago · VGMaintenanceBot bot · 2026-10-13 view diff on Wikidata ↗
    Significant drug interaction → mercaptopurine hydrate, mercaptopurine hydrate, mercaptopurine hydrate +4
    Subclass of → —
    Subject has role → enzyme inhibitor, antimetabolite, antigout agent +3
    Medical condition treated → gout attack, hyperuricemia, gout +1
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbsetqualifier-add:1| */ Mediawiki page id: 3978, Add qualifier to WikiProjectMed ID `Allopurinol`"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.