Y-box binding protein 3

mammalian protein found in Homo sapiens

Protein protein Q21136794

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Y-box binding protein 3

Summary

Y-box binding protein 3 is a protein^[1].

Key Facts

Y-box binding protein 3's instance of is recorded as protein^[2].
Y-box binding protein 3's UniProt protein ID is recorded as P16989^[3].
Y-box binding protein 3's part of is recorded as Nucleic acid-binding, OB-fold^[4].
Y-box binding protein 3's part of is recorded as Cold-shock protein, DNA-binding domain, protein family^[5].
Y-box binding protein 3's part of is recorded as Cold shock domain, protein family^[6].
Y-box binding protein 3's has part is recorded as Cold-shock conserved site^[7].
Y-box binding protein 3's has part is recorded as Cold shock domain^[8].
Y-box binding protein 3's has part is recorded as Cold-shock protein, DNA-binding^[9].
Y-box binding protein 3's RefSeq protein ID is recorded as NP_001138898^[10].
Y-box binding protein 3's RefSeq protein ID is recorded as NP_003642^[11].
Y-box binding protein 3's RefSeq protein ID is recorded as XP_011519173^[12].
Y-box binding protein 3's RefSeq protein ID is recorded as XP_016875611^[13].
Y-box binding protein 3's RefSeq protein ID is recorded as XP_016875612^[14].
Y-box binding protein 3's molecular function is recorded as DNA binding^[15].
Y-box binding protein 3's molecular function is recorded as RNA polymerase II transcription regulatory region sequence-specific DNA binding^[16].
Y-box binding protein 3's molecular function is recorded as transcription corepressor activity^[17].
Y-box binding protein 3's molecular function is recorded as DNA-binding transcription factor activity^[18].
Y-box binding protein 3's molecular function is recorded as mRNA 3'-UTR binding^[19].
Y-box binding protein 3's molecular function is recorded as single-stranded DNA binding^[20].
Y-box binding protein 3's molecular function is recorded as DNA-binding transcription repressor activity, RNA polymerase II-specific^[21].
Y-box binding protein 3's molecular function is recorded as nucleic acid binding^[22].
Y-box binding protein 3's molecular function is recorded as double-stranded DNA binding^[23].
Y-box binding protein 3's molecular function is recorded as RNA binding^[24].
Y-box binding protein 3's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[25].
Y-box binding protein 3's molecular function is recorded as RNA binding^[26].

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Quick Facts

Instance of protein

Part of Nucleic acid-binding, OB-fold, Cold-shock protein, DNA-binding domain, protein family, Cold shock domain, protein family

Properties

Biological process male gonad development, regulation of transcription, DNA-templated, negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress, negative regulation of necroptotic process, positive regulation of cytoplasmic translation, cellular response to tumor necrosis factor, positive regulation of organ growth, negative regulation of apoptotic process, in utero embryonic development, negative regulation of transcription by RNA polymerase II, transcription, DNA-templated, cellular hyperosmotic response, negative regulation of skeletal muscle tissue development, spermatogenesis, response to cold, fertilization, 3'-UTR-mediated mRNA stabilization

Cell component polysome, bicellular tight junction, perinuclear region of cytoplasm, nucleus, cytoplasm, cytosol

Encoded by YBX3

Found in taxon Homo sapiens

Has part(s) Cold-shock conserved site, Cold shock domain, Cold-shock protein, DNA-binding

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, transcription corepressor activity, DNA-binding transcription factor activity, mRNA 3'-UTR binding, single-stranded DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, nucleic acid binding, double-stranded DNA binding, RNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA binding, protein binding, polysome binding

External References (3)

Ensembl protein id ENSP00000228251, ENSP00000279550, ENSP00000485718

Refseq protein id NP_001138898, NP_003642, XP_011519173, XP_016875611, XP_016875612

Uniprot protein id P16989

🏷️ Also known as

en cold-shock domain containing A1 en cold shock domain-containing protein A en cold-shock domain protein A en DNA-binding protein A en single-strand DNA-binding protein NF-GMB en Y-box binding protein 3 en Y-box-binding protein 3 en YBX3 en ZO-1-associated nucleic acid-binding protein

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Y-box binding protein 3 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Y-box binding protein 3 — UniProt protein ID (P352): P16989. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Y-box binding protein 3 — part of (P361): Nucleic acid-binding, OB-fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Y-box binding protein 3 — part of (P361): Cold-shock protein, DNA-binding domain, protein family. wikidata.org.
[6] ↑ Y-box binding protein 3 — part of (P361): Cold shock domain, protein family. wikidata.org.
[7] ↑ Y-box binding protein 3 — has part(s) (P527): Cold-shock conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Y-box binding protein 3 — has part(s) (P527): Cold shock domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Y-box binding protein 3 — has part(s) (P527): Cold-shock protein, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Y-box binding protein 3 — RefSeq protein ID (P637): NP_001138898. Q20641742. Retrieved 2020-05-30. wikidata.org.
[11] ↑ Y-box binding protein 3 — RefSeq protein ID (P637): NP_003642. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ Y-box binding protein 3 — RefSeq protein ID (P637): XP_011519173. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ Y-box binding protein 3 — RefSeq protein ID (P637): XP_016875611. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ Y-box binding protein 3 — RefSeq protein ID (P637): XP_016875612. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ Y-box binding protein 3 — molecular function (P680): DNA binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Y-box binding protein 3 — molecular function (P680): RNA polymerase II transcription regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Y-box binding protein 3 — molecular function (P680): transcription corepressor activity. Cold shock domain proteins repress transcription from the GM-CSF promoter. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Y-box binding protein 3 — molecular function (P680): DNA-binding transcription factor activity. Cold shock domain proteins repress transcription from the GM-CSF promoter. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Y-box binding protein 3 — molecular function (P680): mRNA 3'-UTR binding. Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Y-box binding protein 3 — molecular function (P680): single-stranded DNA binding. GOA. Retrieved 2017-10-17. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Y-box binding protein 3 — molecular function (P680): DNA-binding transcription repressor activity, RNA polymerase II-specific. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Y-box binding protein 3 — molecular function (P680): nucleic acid binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Y-box binding protein 3 — molecular function (P680): double-stranded DNA binding. Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Y-box binding protein 3 — molecular function (P680): RNA binding. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Retrieved 2017-10-17. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Y-box binding protein 3 — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. A census of human transcription factors: function, expression and evolution. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Y-box binding protein 3 — molecular function (P680): RNA binding. The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Y-box binding protein 3 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“Y-box binding protein 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/y-box-binding-protein-3.

BibTeX

@misc{4ortxyz_y-box-binding-protein-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Y-box binding protein 3}}, year = {2026}, url = {https://4ort.xyz/entity/y-box-binding-protein-3}, note = {Accessed: 2026-05-03}}

LLM prompt

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