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XRCC4

protein-coding gene in the species Homo sapiens
Class type of: protein-coding gene Q18032396

Facts

13 properties
Instance of
gene
Subclass of
protein-coding gene
Chromosome
human chromosome 5[13]
Cytogenetic location
5q14.2[16]
Encodes
X-ray repair cross complementing 4, X-ray repair complementing defective repair in Chinese hamster cells 4, isoform CRA_b, X-ray repair complementing defective repair in Chinese hamster cells 4, isoform CRA_a[9][10][11]
Expressed in
testicle, monocyte, gonad, secondary oocyte, ventricular zone, Descending thoracic aorta, Achilles tendon, ganglionic eminence, islet of Langerhans, ascending aorta[17][18][19][20][21][22][23][24][25][26]
Found in taxon
Homo sapiens[12]
Genetic association
microcephalic primordial dwarfism-insulin resistance syndrome[14]
Genomic end
83353787, 82649606[6][7]
Genomic start
83077498, 82373317[4][5]
HomoloGene ID
2555[3]
Ortholog
Xrcc4, Xrcc4, xrcc4[8]
Strand orientation
forward strand[15]
🏷️ Also known as
en hXRCC4 en SSMED en X-ray repair complementing defective repair in Chinese hamster cells 4 en X-ray repair cross complementing 4 en XRCC4
🔖 Identifiers · 13
OpenAlex ID
C145803527
Image (Wikimedia Commons)
Protein XRCC4 PDB 1fu1.png ↗
Ensembl gene ID
ENSG00000152422
Ensembl transcript ID
ENST00000542685, ENST00000282268, ENST00000338635, ENST00000396027, ENST00000509268, ENST00000511817
Entrez Gene ID
7518
Exact match
identifiers.org
Freebase ID
/m/02kfpm1
HGNC ID
12831
HGNC gene symbol
XRCC4
Microsoft Academic ID (discontinued)
145803527
OMIM ID
194363
RefSeq RNA ID
NM_003401, NM_022406, NM_022550, XM_011543626, NM_001318012, NM_001318013, XM_017009827, XM_017009828, XM_047417694, XM_047417695, XM_047417696, XM_047417697, XM_047417698
Show all 13 identifiers +1
UMLS CUI
C1337033

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections
Expressed in 7
testicle, monocyte, gonad, islet of Langerhans, Achilles tendon, ascending aorta, ganglionic eminence
Chromosome 1
human chromosome 5
Found in taxon 1
Homo sapiens
Instance of 1
gene
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Summary

XRCC4 is a gene[1]. XRCC4 is a type of protein-coding gene[2].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . Ensembl Release 87. wikidata.org.
  2. [3] ↑ . NCBI Gene. Retrieved . wikidata.org.
  3. [4] ↑ . ensembl Release 106. wikidata.org.
  4. [5] ↑ . ensembl Release 106. wikidata.org.
  5. [6] ↑ . ensembl Release 106. wikidata.org.
  6. [7] ↑ . ensembl Release 106. wikidata.org.
  7. [8] ↑ . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  8. [9] ↑ . UniProt. Retrieved . wikidata.org.
  9. [10] ↑ . UniProt. Retrieved . wikidata.org.
  10. [11] ↑ . UniProt. Retrieved . wikidata.org.
  11. [12] ↑ . ensembl Release 106. wikidata.org.
  12. [13] ↑ . ensembl Release 106. wikidata.org.
  13. [14] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  14. [15] ↑ . ensembl Release 106. wikidata.org.
  15. [16] ↑ . NCBI Gene. Retrieved . wikidata.org.
  16. [17] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  17. [18] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  18. [19] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  19. [20] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  20. [21] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  21. [22] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  22. [23] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  23. [24] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  24. [25] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  25. [26] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). XRCC4. Retrieved November 6, 2026, from https://4ort.xyz/entity/xrcc4
MLA “XRCC4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 6 Nov. 2026, https://4ort.xyz/entity/xrcc4.
BibTeX @misc{4ortxyz_xrcc4_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{XRCC4}}, year = {2026}, url = {https://4ort.xyz/entity/xrcc4}, note = {Accessed: 2026-11-06}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): XRCC4 — https://4ort.xyz/entity/xrcc4 (retrieved 2026-11-06)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 24w ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    Found in taxon → Homo sapiens
    Chromosome → human chromosome 5
    Subclass of → protein-coding gene
    Encodes → X-ray repair cross complementing 4, X-ray repair complementing defective repair in Chinese hamst, X-ray repair complementing defective repair in Chinese hamst
    + 5 other properties edited (see Wikidata diff for full list)
    "Changed [gsw] labels, descriptions or aliases: QuickStatements 3.0 batch #32527: human gene name and description in Alemannic"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.