WT1 transcription factor

mammalian protein found in Rattus norvegicus

Protein protein Q28558320

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WT1 transcription factor

Summary

WT1 transcription factor is a protein^[1].

Key Facts

WT1 transcription factor's instance of is recorded as protein^[2].
WT1 transcription factor's subclass of is recorded as protein^[3].
WT1 transcription factor's UniProt protein ID is recorded as P49952^[4].
WT1 transcription factor's part of is recorded as Wilm's tumour protein^[5].
WT1 transcription factor's part of is recorded as Zinc finger C2H2 superfamily^[6].
WT1 transcription factor's part of is recorded as Zinc finger C2H2-type, protein family^[7].
WT1 transcription factor's part of is recorded as Wilm's tumour protein, N-terminal domain, protein family^[8].
WT1 transcription factor's has part is recorded as Zinc finger C2H2-type^[9].
WT1 transcription factor's has part is recorded as Wilm's tumour protein, N-terminal^[10].
WT1 transcription factor's RefSeq protein ID is recorded as NP_113722^[11].
WT1 transcription factor's RefSeq protein ID is recorded as XP_006234682^[12].
WT1 transcription factor's RefSeq protein ID is recorded as XP_006234683^[13].
WT1 transcription factor's RefSeq protein ID is recorded as XP_006234684^[14].
WT1 transcription factor's RefSeq protein ID is recorded as XP_017446965^[15].
WT1 transcription factor's RefSeq protein ID is recorded as XP_017446966^[16].
WT1 transcription factor's RefSeq protein ID is recorded as XP_038960216^[17].
WT1 transcription factor's RefSeq protein ID is recorded as XP_038960217^[18].
WT1 transcription factor's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[19].
WT1 transcription factor's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[20].
WT1 transcription factor's molecular function is recorded as nucleic acid binding^[21].
WT1 transcription factor's molecular function is recorded as DNA binding^[22].
WT1 transcription factor's molecular function is recorded as DNA-binding transcription factor activity^[23].
WT1 transcription factor's molecular function is recorded as RNA binding^[24].
WT1 transcription factor's molecular function is recorded as protein binding^[25].
WT1 transcription factor's molecular function is recorded as zinc ion binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Wilm's tumour protein, Zinc finger C2H2 superfamily, Zinc finger C2H2-type, protein family, Wilm's tumour protein, N-terminal domain, protein family

Properties

Biological process vasculogenesis, ureteric bud development, branching involved in ureteric bud morphogenesis, regulation of animal organ formation, regulation of transcription, DNA-templated, regulation of transcription by RNA polymerase II, germ cell development, thorax and anterior abdomen determination, development of the heart, sex-determination system, negative regulation of cell population proliferation, RNA splicing, gonad development, tissue development, negative regulation of translation, negative regulation of cell growth, adrenal gland development, male genitalia development, epithelial cell differentiation, glomerulus development, glomerular basement membrane development, adrenal cortex formation, camera-type eye development, positive regulation of apoptotic process, negative regulation of apoptotic process, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, mesenchymal to epithelial transition, positive regulation of heart growth, diaphragm development, visceral serous pericardium development, cellular response to cAMP, cellular response to gonadotropin stimulus, metanephric mesenchyme development, glomerular visceral epithelial cell differentiation, posterior mesonephric tubule development, metanephric S-shaped body morphogenesis, negative regulation of metanephric glomerular mesangial cell proliferation, positive regulation of male gonad development, negative regulation of female gonad development, positive regulation of metanephric ureteric bud development

Cell component nucleus, nucleoplasm, nucleolus, cytoplasm, nuclear speck

Encoded by Wt1

Found in taxon brown rat

Has part(s) Zinc finger C2H2-type, Wilm's tumour protein, N-terminal

Imported from wholeness_audit_2026-05-02

Molecular function DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific, nucleic acid binding, DNA binding, DNA-binding transcription factor activity, RNA binding, protein binding, zinc ion binding, double-stranded methylated DNA binding, sequence-specific DNA binding, hemi-methylated DNA-binding, metal ion binding, C2H2 zinc finger domain binding

External References (3)

Ensembl protein id ENSRNOP00000060038

Refseq protein id NP_113722, XP_006234682, XP_006234683, XP_006234684, XP_017446965, XP_017446966, XP_038960216, XP_038960217

Uniprot protein id P49952

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ WT1 transcription factor — instance of (P31): protein. Q905695. Retrieved 2021-11-17. wikidata.org.
[3] ↑ WT1 transcription factor — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ WT1 transcription factor — UniProt protein ID (P352): P49952. Q905695. Retrieved 2021-11-17. wikidata.org.
[5] ↑ WT1 transcription factor — part of (P361): Wilm's tumour protein. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ WT1 transcription factor — part of (P361): Zinc finger C2H2 superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ WT1 transcription factor — part of (P361): Zinc finger C2H2-type, protein family. wikidata.org.
[8] ↑ WT1 transcription factor — part of (P361): Wilm's tumour protein, N-terminal domain, protein family. wikidata.org.
[9] ↑ WT1 transcription factor — has part(s) (P527): Zinc finger C2H2-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ WT1 transcription factor — has part(s) (P527): Wilm's tumour protein, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ WT1 transcription factor — RefSeq protein ID (P637): NP_113722. Q20641742. Retrieved 2021-09-07. wikidata.org.
[12] ↑ WT1 transcription factor — RefSeq protein ID (P637): XP_006234682. Q20641742. Retrieved 2021-09-07. wikidata.org.
[13] ↑ WT1 transcription factor — RefSeq protein ID (P637): XP_006234683. Q20641742. Retrieved 2021-09-07. wikidata.org.
[14] ↑ WT1 transcription factor — RefSeq protein ID (P637): XP_006234684. Q20641742. Retrieved 2021-09-07. wikidata.org.
[15] ↑ WT1 transcription factor — RefSeq protein ID (P637): XP_017446965. Q20641742. Retrieved 2021-09-07. wikidata.org.
[16] ↑ WT1 transcription factor — RefSeq protein ID (P637): XP_017446966. Q20641742. Retrieved 2021-09-07. wikidata.org.
[17] ↑ WT1 transcription factor — RefSeq protein ID (P637): XP_038960216. Q20641742. Retrieved 2021-09-07. wikidata.org.
[18] ↑ WT1 transcription factor — RefSeq protein ID (P637): XP_038960217. Q20641742. Retrieved 2021-09-07. wikidata.org.
[19] ↑ WT1 transcription factor — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ WT1 transcription factor — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ WT1 transcription factor — molecular function (P680): nucleic acid binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ WT1 transcription factor — molecular function (P680): DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ WT1 transcription factor — molecular function (P680): DNA-binding transcription factor activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ WT1 transcription factor — molecular function (P680): RNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ WT1 transcription factor — molecular function (P680): protein binding. Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ WT1 transcription factor — molecular function (P680): zinc ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ WT1 transcription factor is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). WT1 transcription factor. Retrieved May 3, 2026, from https://4ort.xyz/entity/wt1-transcription-factor-q28558320

MLA

“WT1 transcription factor.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/wt1-transcription-factor-q28558320.

BibTeX

@misc{4ortxyz_wt1-transcription-factor-q28558320_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{WT1 transcription factor}}, year = {2026}, url = {https://4ort.xyz/entity/wt1-transcription-factor-q28558320}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): WT1 transcription factor — https://4ort.xyz/entity/wt1-transcription-factor-q28558320 (retrieved 2026-05-03)

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