Von Willebrand factor
mammalian protein found in Homo sapiens
Facts
9 properties- Instance of
- protein
- Part of
- Von Willebrand factor-related, von Willebrand factor A-like domain superfamily, Serine protease inhibitor-like superfamily, VWFC domain, protein family, von Willebrand factor, type A, protein family, Cystine knot, C-terminal domain, protein family, von Willebrand factor, VWA N-terminal domain, protein family, Trypsin Inhibitor-like, cysteine rich domain, protein family, von Willebrand factor, type D domain, protein family, Uncharacterised domain, cysteine-rich, protein family[2][3][4][5][6][7][8][9][10][11]
- Biological process
- hemostasis, blood coagulation, intrinsic pathway, platelet degranulation, extracellular matrix organization, blood coagulation, cell-substrate adhesion, cell adhesion, response to wounding, protein homooligomerization, platelet activation[37][38]
- Cell component
- platelet alpha granule, Weibel-Palade body, extracellular region, endoplasmic reticulum, extracellular exosome, platelet alpha granule lumen, extracellular matrix, extracellular region, collagen-containing extracellular matrix, extracellular exosome[29][30][31][32][33][34][35][36]
- Encoded by
- VWF
- Found in taxon
- Homo sapiens
- Has part(s)
- von Willebrand factor, type A, Uncharacterised domain, cysteine-rich, von Willebrand factor, type D domain, Trypsin Inhibitor-like, cysteine rich domain, Cystine knot, C-terminal, VWFC domain, von Willebrand factor, VWA N-terminal domain[12][13][14][15][16][17][18]
- Molecular function
- chaperone binding, protein homodimerization activity, collagen binding, protein N-terminus binding, immunoglobulin binding, protease binding, integrin binding, identical protein binding, protein binding, extracellular matrix structural constituent, extracellular matrix structural constituent, extracellular matrix structural constituent[19][20][21][22][23][24][25][26][27][28]
- Named after
- Erik Adolf von Willebrand[1]
🏷️ Also known as
en uniprot:P04275
en coagulation factor VIII VWF
en Von Willebrand factor
en VWF
en von Willebrand factor
ar عامل فون ويليبراند
ar Von Willebrand factor
cs VWF
cs Von Willebrandův faktor
de Von-Willebrand-Faktor
de Von Willebrand-Faktor
de Faktor VIII-assoziiertes Antigen
de VWF
de Willebrand-Faktor
es Factor de von Willebrand
es Factor von Willebrand
fa عامل فون ویلبراند
fi Von Willebrand -tekijä
fr PTTa
fr cofacteur de la ristocetine
🔖 Identifiers · 12
- OpenAlex ID
- C2779394231
- ATC code
- B02BD10
- Ensembl protein ID
- ENSP00000261405, ENSP00000459134, ENSP00000461331
- Exact match
- purl.uniprot.org
- Freebase ID
- /m/02xr1z
- MeSH descriptor ID
- D014841
- MeSH tree code
- D12.776.124.125.920, D23.119.985
- Microsoft Academic ID (discontinued)
- 2779394231, 2908911547
- PDB structure ID
- 1AO3, 1ATZ, 1AUQ, 1FE8, 1FNS, 1IJB, 1IJK, 1M10, 1OAK, 1U0N, 2ADF, 3GXB, 3HXO, 3HXQ, 3PPV, 3PPW, 3PPX, 3PPY, 3ZQK, 4DMU, 1UEX, 2MHP, 2MHQ, 4C29, 4C2A, 4C2B, 4NT5, 5BV8
- RefSeq protein ID
- NP_000543
- UniProt protein ID
- P04275
- Wellcome Collection concept ID
- brhvhyuw
🔗 Connections
Cell component 5
Biological process 3
Found in taxon 1
Instance of 1
Molecular function 1
Named after 1
← Has cause 1
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