Von Willebrand factor

mammalian protein found in Homo sapiens
Protein protein Q412310
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Von Willebrand factor

Summary

Von Willebrand factor is a protein[1]. It ranks in the top 5% of protein entities by monthly Wikipedia readership (530 views/month).[2]

Key Facts

  • Von Willebrand factor's instance of is recorded as protein[3].
  • Erik Adolf von Willebrand is named after Von Willebrand factor[4].
  • Von Willebrand factor is part of Von Willebrand factor-related[5].
  • Von Willebrand factor is part of von Willebrand factor A-like domain superfamily[6].
  • Von Willebrand factor is part of Serine protease inhibitor-like superfamily[7].
  • Von Willebrand factor is part of VWFC domain, protein family[8].
  • Von Willebrand factor is part of von Willebrand factor, type A, protein family[9].
  • Von Willebrand factor is part of Cystine knot, C-terminal domain, protein family[10].
  • Von Willebrand factor is part of von Willebrand factor, VWA N-terminal domain, protein family[11].
  • Von Willebrand factor is part of Trypsin Inhibitor-like, cysteine rich domain, protein family[12].
  • Von Willebrand factor is part of von Willebrand factor, type D domain, protein family[13].
  • Von Willebrand factor is part of Uncharacterised domain, cysteine-rich, protein family[14].
  • Von Willebrand factor's Commons category is recorded as Von willebrand factor[15].
  • Von Willebrand factor comprises von Willebrand factor, type A[16].
  • Von Willebrand factor comprises Uncharacterised domain, cysteine-rich[17].
  • Von Willebrand factor comprises von Willebrand factor, type D domain[18].
  • Von Willebrand factor comprises Trypsin Inhibitor-like, cysteine rich domain[19].
  • Von Willebrand factor comprises Cystine knot, C-terminal[20].
  • Von Willebrand factor comprises VWFC domain[21].
  • Von Willebrand factor comprises von Willebrand factor, VWA N-terminal domain[22].
  • Von Willebrand factor's molecular function is recorded as chaperone binding[23].
  • Von Willebrand factor's molecular function is recorded as protein homodimerization activity[24].
  • Von Willebrand factor's molecular function is recorded as collagen binding[25].
  • Von Willebrand factor's molecular function is recorded as protein N-terminus binding[26].
  • Von Willebrand factor's molecular function is recorded as immunoglobulin binding[27].

Why It Matters

Von Willebrand factor ranks in the top 5% of protein entities by monthly Wikipedia readership (530 views/month).[2] It has Wikipedia articles in 19 language editions, a strong signal of global cultural recognition.[28] It is known by 25 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . wikidata.org.
  9. [11] . wikidata.org.
  10. [12] . wikidata.org.
  11. [13] . wikidata.org.
  12. [14] . wikidata.org.
  13. [15] . wikidata.org.
  14. [16] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . A novel von Willebrand disease-causing mutation (Arg273Trp) in the von Willebrand factor propeptide that results in defective multimerization and secretion. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . A novel von Willebrand disease-causing mutation (Arg273Trp) in the von Willebrand factor propeptide that results in defective multimerization and secretion. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . 150-kD von Willebrand factor binding protein extracted from human vascular subendothelium is type VI collagen. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . Identification of three tyrosine residues of glycoprotein Ib alpha with distinct roles in von Willebrand factor and alpha-thrombin binding. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . The relationship of N-linked glycosylation and heavy chain-binding protein association with the secretion of glycoproteins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Von Willebrand factor. Retrieved May 3, 2026, from https://4ort.xyz/entity/von-willebrand-factor
MLA “Von Willebrand factor.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/von-willebrand-factor.
BibTeX @misc{4ortxyz_von-willebrand-factor_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Von Willebrand factor}}, year = {2026}, url = {https://4ort.xyz/entity/von-willebrand-factor}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Von Willebrand factor — https://4ort.xyz/entity/von-willebrand-factor (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 8d ago · Dirac · 2026-07-20 view diff on Wikidata ↗
    Molecular function chaperone binding, protein homodimerization activity, collagen binding +9
    Part of
    Cell component platelet alpha granule, Weibel-Palade body, extracellular region +7
    Instance of protein
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P18]]: PBB Protein VWF image.jpg, [[:toollabs:quickstatements/#/batch/261337|batch #261337]]"
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