Ubiquitin specific peptidase 7

mammalian protein found in Homo sapiens
Protein protein Q21109614
Press Enter · cited answer in seconds

Summary

Ubiquitin specific peptidase 7 is a protein[1]. It is known by 10 alternative names across languages and contexts.[2]

Key Facts

  • Part of: TRAF-like[3], Papain-like cysteine peptidase superfamily[4], Peptidase C19, ubiquitin carboxyl-terminal hydrolase family[5], MATH/TRAF domain, protein family[6], Ubiquitin carboxyl-terminal hydrolase, C-terminal domain, protein family[7], Ubiquitin specific protease domain, protein family[8], Ubiquitin specific protease, conserved site, protein family[9], Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain, protein family[10]
  • Has part(s): Peptidase C19, ubiquitin carboxyl-terminal hydrolase[11], Ubiquitin specific protease domain[12], Ubiquitin specific protease, conserved site[13], MATH/TRAF domain[14], Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain[15], Ubiquitin carboxyl-terminal hydrolase, C-terminal[16]
  • Molecular function: cysteine-type peptidase activity[17], p53 binding[18], transcription factor binding[19], peptidase activity[20], protein C-terminus binding[21], protein binding[22], thiol-dependent deubiquitinase[23], cysteine-type endopeptidase activity[24], hydrolase activity[25], ubiquitin protein ligase binding[26], deubiquitinase activity[27], Lys48-specific deubiquitinase activity[28]
  • Cell component: cytoplasm[29], PML body[30], nuclear body[31], nucleoplasm[32], nucleus[33], cytosol[34], chromosome[35]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . USP10 regulates p53 localization and stability by deubiquitinating p53. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Deubiquitinating enzymes: a new class of biological regulators. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . Noncanonical regulation of alkylation damage resistance by the OTUD 4 deubiquitinase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Ubiquitin specific peptidase 7. Retrieved May 3, 2026, from https://4ort.xyz/entity/ubiquitin-specific-peptidase-7
MLA “Ubiquitin specific peptidase 7.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ubiquitin-specific-peptidase-7.
BibTeX @misc{4ortxyz_ubiquitin-specific-peptidase-7_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Ubiquitin specific peptidase 7}}, year = {2026}, url = {https://4ort.xyz/entity/ubiquitin-specific-peptidase-7}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Ubiquitin specific peptidase 7 — https://4ort.xyz/entity/ubiquitin-specific-peptidase-7 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/ubiquitin-specific-peptidase-7 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 11w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Found in taxon → Homo sapiens
    Mesh tree code → D08.811.037.750.750, D08.811.277.656.300.887.875
    Wikidata description → mammalian protein found in Homo sapiens
    Pdb structure id → 1NB8, 1NBF, 1YY6 +25
    + 14 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 3.4.19.12, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.