Ubiquitin conjugating enzyme E2 L3

mammalian protein found in Homo sapiens

Protein protein Q21130015

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Ubiquitin conjugating enzyme E2 L3

Summary

Ubiquitin conjugating enzyme E2 L3 is a protein^[1].

Key Facts

Ubiquitin conjugating enzyme E2 L3's instance of is recorded as protein^[2].
Ubiquitin conjugating enzyme E2 L3's UniProt protein ID is recorded as P68036^[3].
Ubiquitin conjugating enzyme E2 L3's part of is recorded as Ubiquitin-conjugating enzyme/RWD-like^[4].
Ubiquitin conjugating enzyme E2 L3's part of is recorded as Ubiquitin-conjugating enzyme E2 family^[5].
Ubiquitin conjugating enzyme E2 L3's part of is recorded as Ubiquitin-conjugating enzyme, active site, protein family^[6].
Ubiquitin conjugating enzyme E2 L3's has part is recorded as Ubiquitin-conjugating enzyme E2^[7].
Ubiquitin conjugating enzyme E2 L3's has part is recorded as Ubiquitin-conjugating enzyme, active site^[8].
Ubiquitin conjugating enzyme E2 L3's RefSeq protein ID is recorded as NP_001243284^[9].
Ubiquitin conjugating enzyme E2 L3's RefSeq protein ID is recorded as NP_001243285^[10].
Ubiquitin conjugating enzyme E2 L3's RefSeq protein ID is recorded as NP_003338^[11].
Ubiquitin conjugating enzyme E2 L3's RefSeq protein ID is recorded as XP_016884424^[12].
Ubiquitin conjugating enzyme E2 L3's PDB structure ID is recorded as 1C4Z^[13].
Ubiquitin conjugating enzyme E2 L3's PDB structure ID is recorded as 1FBV^[14].
Ubiquitin conjugating enzyme E2 L3's PDB structure ID is recorded as 3SQV^[15].
Ubiquitin conjugating enzyme E2 L3's PDB structure ID is recorded as 3SY2^[16].
Ubiquitin conjugating enzyme E2 L3's PDB structure ID is recorded as 4Q5E^[17].
Ubiquitin conjugating enzyme E2 L3's PDB structure ID is recorded as 4Q5H^[18].
Ubiquitin conjugating enzyme E2 L3's PDB structure ID is recorded as 5HPT^[19].
Ubiquitin conjugating enzyme E2 L3's molecular function is recorded as transferase activity^[20].
Ubiquitin conjugating enzyme E2 L3's molecular function is recorded as nucleotide binding^[21].
Ubiquitin conjugating enzyme E2 L3's molecular function is recorded as transcription coactivator activity^[22].
Ubiquitin conjugating enzyme E2 L3's molecular function is recorded as ubiquitin-protein transferase activity^[23].
Ubiquitin conjugating enzyme E2 L3's molecular function is recorded as protein binding^[24].
Ubiquitin conjugating enzyme E2 L3's molecular function is recorded as ubiquitin-protein transferase activator activity^[25].
Ubiquitin conjugating enzyme E2 L3's molecular function is recorded as enzyme binding^[26].

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Quick Facts

Instance of protein

Part of Ubiquitin-conjugating enzyme/RWD-like, Ubiquitin-conjugating enzyme E2 family, Ubiquitin-conjugating enzyme, active site, protein family

Properties

Biological process cell cycle phase transition, cellular response to steroid hormone stimulus, regulation of transcription, DNA-templated, ubiquitin-dependent protein catabolic process, positive regulation of protein targeting to mitochondrion, protein polyubiquitination, transcription, DNA-templated, protein K11-linked ubiquitination, cellular response to glucocorticoid stimulus, positive regulation of ubiquitin-protein transferase activity, cell population proliferation, positive regulation of protein ubiquitination, protein ubiquitination

Cell component cytoplasm, ubiquitin ligase complex, extracellular exosome, nucleus, nucleoplasm, cytosol

Encoded by UBE2L3

Found in taxon Homo sapiens

Has part(s) Ubiquitin-conjugating enzyme E2, Ubiquitin-conjugating enzyme, active site

Imported from wholeness_audit_2026-05-02

Molecular function transferase activity, nucleotide binding, transcription coactivator activity, ubiquitin-protein transferase activity, protein binding, ubiquitin-protein transferase activator activity, enzyme binding, ATP binding, ubiquitin protein ligase binding, RNA binding, ubiquitin conjugating enzyme activity

External References (4)

Ensembl protein id ENSP00000344259, ENSP00000400906, ENSP00000445931

Pdb structure id 1C4Z, 1FBV, 3SQV, 3SY2, 4Q5E, 4Q5H, 5HPT

Refseq protein id NP_001243284, NP_001243285, NP_003338, XP_016884424

Uniprot protein id P68036

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Ubiquitin conjugating enzyme E2 L3 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Ubiquitin conjugating enzyme E2 L3 — UniProt protein ID (P352): P68036. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Ubiquitin conjugating enzyme E2 L3 — part of (P361): Ubiquitin-conjugating enzyme/RWD-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Ubiquitin conjugating enzyme E2 L3 — part of (P361): Ubiquitin-conjugating enzyme E2 family. wikidata.org.
[6] ↑ Ubiquitin conjugating enzyme E2 L3 — part of (P361): Ubiquitin-conjugating enzyme, active site, protein family. wikidata.org.
[7] ↑ Ubiquitin conjugating enzyme E2 L3 — has part(s) (P527): Ubiquitin-conjugating enzyme E2. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Ubiquitin conjugating enzyme E2 L3 — has part(s) (P527): Ubiquitin-conjugating enzyme, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Ubiquitin conjugating enzyme E2 L3 — RefSeq protein ID (P637): NP_001243284. Q20641742. Retrieved 2020-05-30. wikidata.org.
[10] ↑ Ubiquitin conjugating enzyme E2 L3 — RefSeq protein ID (P637): NP_001243285. Q20641742. Retrieved 2020-05-30. wikidata.org.
[11] ↑ Ubiquitin conjugating enzyme E2 L3 — RefSeq protein ID (P637): NP_003338. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ Ubiquitin conjugating enzyme E2 L3 — RefSeq protein ID (P637): XP_016884424. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ Ubiquitin conjugating enzyme E2 L3 — PDB structure ID (P638): 1C4Z. Q905695. Retrieved 2016-03-20. wikidata.org.
[14] ↑ Ubiquitin conjugating enzyme E2 L3 — PDB structure ID (P638): 1FBV. Q905695. Retrieved 2016-03-20. wikidata.org.
[15] ↑ Ubiquitin conjugating enzyme E2 L3 — PDB structure ID (P638): 3SQV. Q905695. Retrieved 2016-03-20. wikidata.org.
[16] ↑ Ubiquitin conjugating enzyme E2 L3 — PDB structure ID (P638): 3SY2. Q905695. Retrieved 2016-03-20. wikidata.org.
[17] ↑ Ubiquitin conjugating enzyme E2 L3 — PDB structure ID (P638): 4Q5E. Q905695. Retrieved 2016-03-20. wikidata.org.
[18] ↑ Ubiquitin conjugating enzyme E2 L3 — PDB structure ID (P638): 4Q5H. Q905695. Retrieved 2016-03-20. wikidata.org.
[19] ↑ Ubiquitin conjugating enzyme E2 L3 — PDB structure ID (P638): 5HPT. Q905695. Retrieved 2016-03-20. wikidata.org.
[20] ↑ Ubiquitin conjugating enzyme E2 L3 — molecular function (P680): transferase activity. GOA. Retrieved 2017-10-17. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Ubiquitin conjugating enzyme E2 L3 — molecular function (P680): nucleotide binding. GOA. Retrieved 2017-10-17. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Ubiquitin conjugating enzyme E2 L3 — molecular function (P680): transcription coactivator activity. The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors. Retrieved 2017-10-17. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Ubiquitin conjugating enzyme E2 L3 — molecular function (P680): ubiquitin-protein transferase activity. Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5. Retrieved 2017-10-17. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Ubiquitin conjugating enzyme E2 L3 — molecular function (P680): protein binding. UbcH7 interacts with the glucocorticoid receptor and mediates receptor autoregulation. Retrieved 2017-10-17. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Ubiquitin conjugating enzyme E2 L3 — molecular function (P680): ubiquitin-protein transferase activator activity. Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Retrieved 2017-10-17. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Ubiquitin conjugating enzyme E2 L3 — molecular function (P680): enzyme binding. A human ubiquitin conjugating enzyme, L-UBC, maps in the Alzheimer's disease locus on chromosome 14q24.3. Retrieved 2017-10-17. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Ubiquitin conjugating enzyme E2 L3 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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BibTeX

@misc{4ortxyz_ubiquitin-conjugating-enzyme-e2-l3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Ubiquitin conjugating enzyme E2 L3}}, year = {2026}, url = {https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-l3}, note = {Accessed: 2026-05-03}}

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