Ubiquitin conjugating enzyme E2 I

mammalian protein found in Homo sapiens

Protein protein Q21130684

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Ubiquitin conjugating enzyme E2 I

Summary

Ubiquitin conjugating enzyme E2 I is a protein^[1].

Key Facts

Ubiquitin conjugating enzyme E2 I's instance of is recorded as protein^[2].
Ubiquitin conjugating enzyme E2 I's UniProt protein ID is recorded as P63279^[3].
Ubiquitin conjugating enzyme E2 I's part of is recorded as SUMO-conjugating enzyme Ubc9^[4].
Ubiquitin conjugating enzyme E2 I's part of is recorded as Ubiquitin-conjugating enzyme/RWD-like^[5].
Ubiquitin conjugating enzyme E2 I's part of is recorded as Peroxisomal Protein Importer^[6].
Ubiquitin conjugating enzyme E2 I's part of is recorded as Ubiquitin-conjugating enzyme E2 family^[7].
Ubiquitin conjugating enzyme E2 I's part of is recorded as Ubiquitin-conjugating enzyme, active site, protein family^[8].
Ubiquitin conjugating enzyme E2 I's has part is recorded as Ubiquitin-conjugating enzyme E2^[9].
Ubiquitin conjugating enzyme E2 I's has part is recorded as Ubiquitin-conjugating enzyme, active site^[10].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as NP_003336^[11].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as NP_919235^[12].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as NP_919236^[13].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as NP_919237^[14].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as XP_005255597^[15].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as XP_005255598^[16].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as XP_011520946^[17].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as XP_011520947^[18].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as XP_016879129^[19].
Ubiquitin conjugating enzyme E2 I's RefSeq protein ID is recorded as XP_024306200^[20].
Ubiquitin conjugating enzyme E2 I's PDB structure ID is recorded as 1A3S^[21].
Ubiquitin conjugating enzyme E2 I's PDB structure ID is recorded as 1KPS^[22].
Ubiquitin conjugating enzyme E2 I's PDB structure ID is recorded as 1Z5S^[23].
Ubiquitin conjugating enzyme E2 I's PDB structure ID is recorded as 2GRN^[24].
Ubiquitin conjugating enzyme E2 I's PDB structure ID is recorded as 2GRO^[25].
Ubiquitin conjugating enzyme E2 I's PDB structure ID is recorded as 2GRP^[26].

⭐ Popularity Graph

1/100 established

Quick Facts

Instance of protein

Part of SUMO-conjugating enzyme Ubc9, Ubiquitin-conjugating enzyme/RWD-like, Peroxisomal Protein Importer, Ubiquitin-conjugating enzyme E2 family, Ubiquitin-conjugating enzyme, active site, protein family

Properties

Biological process ubiquitin-dependent protein catabolic process, chromosome segregation, protein sumoylation, cell division, global genome nucleotide-excision repair, positive regulation of I-kappaB kinase/NF-kappaB signaling, cell cycle, positive regulation of SUMO transferase activity, viral process, negative regulation of transcription, DNA-templated, negative regulation of transcription by RNA polymerase II, regulation of signaling receptor activity, protein ubiquitination, positive regulation of intracellular steroid hormone receptor signaling pathway, proteasome-mediated ubiquitin-dependent protein catabolic process, positive regulation of DNA-binding transcription factor activity, protein sumoylation

Cell component cytoplasm, PML body, nuclear body, nucleoplasm, transferase complex, synaptonemal complex, nucleus, cytosol, sumoylated E2 ligase complex, fibrillar center, nuclear envelope, dendrite, synapse, nucleus, nuclear envelope

Encoded by UBE2I

Found in taxon Homo sapiens

Has part(s) Ubiquitin-conjugating enzyme E2, Ubiquitin-conjugating enzyme, active site

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, SUMO transferase activity, ubiquitin protein ligase activity, transcription factor binding, RING-like zinc finger domain binding, HLH domain binding, protein binding, enzyme binding, SUMO conjugating enzyme activity, ATP binding, ubiquitin protein ligase binding, transferase activity, RNA binding, small protein activating enzyme binding, ubiquitin-protein transferase activity, protein C-terminus binding, bHLH transcription factor binding, RNA binding, SUMO conjugating enzyme activity

External References (5)

Ensembl protein id ENSP00000324897, ENSP00000348056, ENSP00000380649, ENSP00000380650, ENSP00000384568, ENSP00000385009, ENSP00000457064, ENSP00000384361, ENSP00000455252, ENSP00000455893, ENSP00000456188, ENSP00000490882

Pdb structure id 1A3S, 1KPS, 1Z5S, 2GRN, 2GRO, 2GRP, 2GRQ, 2GRR, 2O25, 2PE6, 2PX9, 2XWU, 3A4S, 3UIN, 3UIO, 3UIP, 4Y1L, 4W5V, 2VRR, 5D2M, 5F6D, 5F6U, 5F6W, 5F6E, 5F6X, 5F6V, 5F6Y

Refseq protein id NP_003336, NP_919235, NP_919236, NP_919237, XP_005255597, XP_005255598, XP_011520946, XP_011520947, XP_016879129, XP_024306200

Transporter classification database id 3.A.20.1.1

Uniprot protein id P63279

🏷️ Also known as

en p18 en RING-type E3 SUMO transferase UBC9 en SUMO-1-protein ligase en SUMO-conjugating enzyme UBC9 en SUMO-protein ligase en UBE2I en ubiquitin carrier protein 9 en ubiquitin carrier protein I en ubiquitin conjugating enzyme 9 en Ubiquitin conjugating enzyme E2 I en Ubiquitin-conjugating enzyme E2 I en ubiquitin conjugating enzyme E2I en ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9) en ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) en ubiquitin-conjugating enzyme UbcE2A en ubiquitin-like protein SUMO-1 conjugating enzyme en ubiquitin-protein ligase E2I en ubiquitin-protein ligase I

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Ubiquitin conjugating enzyme E2 I — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Ubiquitin conjugating enzyme E2 I — UniProt protein ID (P352): P63279. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Ubiquitin conjugating enzyme E2 I — part of (P361): SUMO-conjugating enzyme Ubc9. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Ubiquitin conjugating enzyme E2 I — part of (P361): Ubiquitin-conjugating enzyme/RWD-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Ubiquitin conjugating enzyme E2 I — part of (P361): Peroxisomal Protein Importer. Retrieved 2019-10-02. wikidata.org.
[7] ↑ Ubiquitin conjugating enzyme E2 I — part of (P361): Ubiquitin-conjugating enzyme E2 family. wikidata.org.
[8] ↑ Ubiquitin conjugating enzyme E2 I — part of (P361): Ubiquitin-conjugating enzyme, active site, protein family. wikidata.org.
[9] ↑ Ubiquitin conjugating enzyme E2 I — has part(s) (P527): Ubiquitin-conjugating enzyme E2. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Ubiquitin conjugating enzyme E2 I — has part(s) (P527): Ubiquitin-conjugating enzyme, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): NP_003336. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): NP_919235. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): NP_919236. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): NP_919237. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): XP_005255597. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): XP_005255598. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): XP_011520946. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): XP_011520947. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): XP_016879129. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Ubiquitin conjugating enzyme E2 I — RefSeq protein ID (P637): XP_024306200. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Ubiquitin conjugating enzyme E2 I — PDB structure ID (P638): 1A3S. Q905695. Retrieved 2016-08-09. wikidata.org.
[22] ↑ Ubiquitin conjugating enzyme E2 I — PDB structure ID (P638): 1KPS. Q905695. Retrieved 2016-08-09. wikidata.org.
[23] ↑ Ubiquitin conjugating enzyme E2 I — PDB structure ID (P638): 1Z5S. Q905695. Retrieved 2016-08-09. wikidata.org.
[24] ↑ Ubiquitin conjugating enzyme E2 I — PDB structure ID (P638): 2GRN. Q905695. Retrieved 2016-08-09. wikidata.org.
[25] ↑ Ubiquitin conjugating enzyme E2 I — PDB structure ID (P638): 2GRO. Q905695. Retrieved 2016-08-09. wikidata.org.
[26] ↑ Ubiquitin conjugating enzyme E2 I — PDB structure ID (P638): 2GRP. Q905695. Retrieved 2016-08-09. wikidata.org.

Class ancestry

[1] ↑ Ubiquitin conjugating enzyme E2 I is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

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BibTeX

@misc{4ortxyz_ubiquitin-conjugating-enzyme-e2-i_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Ubiquitin conjugating enzyme E2 I}}, year = {2026}, url = {https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-i}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Ubiquitin conjugating enzyme E2 I — https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-i (retrieved 2026-05-03)

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