Ubiquitin conjugating enzyme E2 B

mammalian protein found in Homo sapiens
Protein protein Q21135165
Press Enter · cited answer in seconds

Summary

Ubiquitin conjugating enzyme E2 B is a protein[1]. It is known by 13 alternative names across languages and contexts.[2]

Key Facts

  • Part of: Ubiquitin-conjugating enzyme/RWD-like[3], Ubiquitin-conjugating enzyme E2 family[4], Ubiquitin-conjugating enzyme, active site, protein family[5]
  • Has part(s): Ubiquitin-conjugating enzyme E2[6], Ubiquitin-conjugating enzyme, active site[7]
  • Molecular function: transferase activity[8], nucleotide binding[9], ubiquitin protein ligase activity[10], ubiquitin-protein transferase activity[11], protein binding[12], ATP binding[13], ubiquitin conjugating enzyme activity[14], ubiquitin protein ligase binding[15]
  • Cell component: cytoplasm[16], membrane[17], plasma membrane[18], replication fork[19], HULC complex[20], nucleoplasm[21], XY body[22], chromatin[23], nucleus[24]
  • Biological process: chiasma assembly[25], histone H2A ubiquitination[26], negative regulation of cAMP-mediated signaling[27], postreplication repair[28], ubiquitin-dependent protein catabolic process[29], protein K63-linked ubiquitination[30], meiotic telomere clustering[31], positive regulation of reciprocal meiotic recombination[32], protein stabilization[33], protein polyubiquitination[34], negative regulation of apoptotic process[35], in utero embryonic development[36], protein monoubiquitination[37], sperm axoneme assembly[38]
  • Encoded by: UBE2B[39]
  • Found in taxon: Homo sapiens[40]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . Rad6B is a positive regulator of beta-catenin stabilization. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . The human RAD18 gene product interacts with HHR6A and HHR6B. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Rad6B is a positive regulator of beta-catenin stabilization. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . Rad6B is a positive regulator of beta-catenin stabilization. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . Rad6B is a positive regulator of beta-catenin stabilization. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . Rad6B is a positive regulator of beta-catenin stabilization. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . Rad6B is a positive regulator of beta-catenin stabilization. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  37. [39] ↑ . UniProt. Retrieved . wikidata.org.
  38. [40] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Ubiquitin conjugating enzyme E2 B. Retrieved May 3, 2026, from https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-b-q21135165
MLA “Ubiquitin conjugating enzyme E2 B.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-b-q21135165.
BibTeX @misc{4ortxyz_ubiquitin-conjugating-enzyme-e2-b-q21135165_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Ubiquitin conjugating enzyme E2 B}}, year = {2026}, url = {https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-b-q21135165}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Ubiquitin conjugating enzyme E2 B — https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-b-q21135165 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/ubiquitin-conjugating-enzyme-e2-b-q21135165 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → UBE2B
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → transferase activity, nucleotide binding, ubiquitin protein ligase activity +6
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.3.2.23, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.