Tyrosyl-tRNA synthetase 1

mammalian protein found in Homo sapiens
Protein protein Q21124606
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Summary

Tyrosyl-tRNA synthetase 1 is a protein[1]. It is known by 10 alternative names across languages and contexts.[2]

Key Facts

  • Part of: Nucleic acid-binding, OB-fold[3], tyrosine-tRNA ligase[4], Rossmann fold[5], tRNA-binding domain, protein family[6]
  • Has part(s): tRNA-binding domain[7]
  • Molecular function: aminoacyl-tRNA ligase activity[8], nucleotide binding[9], signal transducer activity[10], ligase activity[11], protein binding[12], interleukin-8 receptor binding[13], ATP binding[14], tyrosine-tRNA ligase activity[15], tRNA binding[16], RNA binding[17]
  • Cell component: extracellular space[18], cytoplasm[19], nuclear body[20], cytosol[21], aminoacyl-tRNA synthetase multienzyme complex[22], methionyl glutamyl tRNA synthetase complex[23]
  • Biological process: tyrosyl-tRNA aminoacylation[24], protein biosynthesis[25], apoptotic process[26], signal transduction[27], tRNA aminoacylation for protein translation[28]
  • Encoded by: YARS1[29]
  • Found in taxon: Homo sapiens[30]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . Human tyrosyl-tRNA synthetase shares amino acid sequence homology with a putative cytokine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Human tyrosyl-tRNA synthetase shares amino acid sequence homology with a putative cytokine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . UniProt. Retrieved . wikidata.org.
  28. [30] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Tyrosyl-tRNA synthetase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/tyrosyl-trna-synthetase-1
MLA “Tyrosyl-tRNA synthetase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/tyrosyl-trna-synthetase-1.
BibTeX @misc{4ortxyz_tyrosyl-trna-synthetase-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Tyrosyl-tRNA synthetase 1}}, year = {2026}, url = {https://4ort.xyz/entity/tyrosyl-trna-synthetase-1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Tyrosyl-tRNA synthetase 1 — https://4ort.xyz/entity/tyrosyl-trna-synthetase-1 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → YARS1
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → aminoacyl-tRNA ligase activity, nucleotide binding, signal transducer activity +9
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 6.1.1.1, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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