Two pore segment channel 2

mammalian protein found in Homo sapiens
Protein protein Q21103323
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Two pore segment channel 2

Summary

Two pore segment channel 2 is a protein[1].

Key Facts

  • Two pore segment channel 2's instance of is recorded as protein[2].
  • Two pore segment channel 2's physically interacts with is recorded as phosphatidyl (3,5) inositol biphosphate[3].
  • Two pore segment channel 2's physically interacts with is recorded as verapamil[4].
  • Two pore segment channel 2's UniProt protein ID is recorded as Q8NHX9[5].
  • Two pore segment channel 2's part of is recorded as Two pore calcium channel protein 2[6].
  • Two pore segment channel 2's part of is recorded as Voltage-dependent channel domain superfamily[7].
  • Two pore segment channel 2's part of is recorded as voltage-gated ion channel[8].
  • Two pore segment channel 2's part of is recorded as Ion transport domain, protein family[9].
  • Two pore segment channel 2's has part is recorded as Ion transport domain[10].
  • Two pore segment channel 2's RefSeq protein ID is recorded as NP_620714[11].
  • Two pore segment channel 2's molecular function is recorded as calcium channel activity[12].
  • Two pore segment channel 2's molecular function is recorded as voltage-gated ion channel activity[13].
  • Two pore segment channel 2's molecular function is recorded as ion channel activity[14].
  • Two pore segment channel 2's molecular function is recorded as protein binding[15].
  • Two pore segment channel 2's molecular function is recorded as identical protein binding[16].
  • Two pore segment channel 2's molecular function is recorded as protein kinase binding[17].
  • Two pore segment channel 2's molecular function is recorded as NAADP-sensitive calcium-release channel activity[18].
  • Two pore segment channel 2's molecular function is recorded as voltage-gated calcium channel activity[19].
  • Two pore segment channel 2's molecular function is recorded as NAADP-sensitive calcium-release channel activity[20].
  • Two pore segment channel 2's cell component is recorded as integral component of membrane[21].
  • Two pore segment channel 2's cell component is recorded as membrane[22].
  • Two pore segment channel 2's cell component is recorded as plasma membrane[23].
  • Two pore segment channel 2's cell component is recorded as endosome membrane[24].
  • Two pore segment channel 2's cell component is recorded as lysosome[25].
  • Two pore segment channel 2's cell component is recorded as lysosomal membrane[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [5] . Q905695. Retrieved . wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . Retrieved . wikidata.org.
  8. [9] . wikidata.org.
  9. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . Q20641742. Retrieved . wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Two-pore channels form homo- and heterodimers. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Two pore segment channel 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/two-pore-segment-channel-2
MLA “Two pore segment channel 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/two-pore-segment-channel-2.
BibTeX @misc{4ortxyz_two-pore-segment-channel-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Two pore segment channel 2}}, year = {2026}, url = {https://4ort.xyz/entity/two-pore-segment-channel-2}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Two pore segment channel 2 — https://4ort.xyz/entity/two-pore-segment-channel-2 (retrieved 2026-05-03)

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