Twinkle mtDNA helicase

mammalian protein found in Homo sapiens
Protein protein Q21443395
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Twinkle mtDNA helicase

Summary

Twinkle mtDNA helicase is a protein[1]. It draws 11 Wikipedia views per month (protein category, ranking #152 of 987).[2]

Key Facts

  • Twinkle mtDNA helicase's instance of is recorded as protein[3].
  • Twinkle mtDNA helicase is a type of protein[4].
  • Twinkle mtDNA helicase is part of P-loop containing nucleoside triphosphate hydrolase[5].
  • Twinkle mtDNA helicase is part of Archaeal primase DnaG/twinkle, TOPRIM domain, protein family[6].
  • Twinkle mtDNA helicase is part of DNA helicase, DnaB-like, C-terminal domain, protein family[7].
  • Twinkle mtDNA helicase comprises DNA helicase, DnaB-like, C-terminal[8].
  • Twinkle mtDNA helicase comprises Archaeal primase DnaG/twinkle, TOPRIM domain[9].
  • Twinkle mtDNA helicase's molecular function is recorded as protease binding[10].
  • Twinkle mtDNA helicase's molecular function is recorded as nucleotide binding[11].
  • Twinkle mtDNA helicase's molecular function is recorded as DNA helicase activity[12].
  • Twinkle mtDNA helicase's molecular function is recorded as hydrolase activity[13].
  • Twinkle mtDNA helicase's molecular function is recorded as ATP binding[14].
  • Twinkle mtDNA helicase's molecular function is recorded as helicase activity[15].
  • Twinkle mtDNA helicase's molecular function is recorded as single-stranded DNA binding[16].
  • Twinkle mtDNA helicase's molecular function is recorded as 5'-3' DNA helicase activity[17].
  • Twinkle mtDNA helicase's cell component is recorded as mitochondrial matrix[18].
  • Twinkle mtDNA helicase's cell component is recorded as mitochondrial nucleoid[19].
  • Twinkle mtDNA helicase's cell component is recorded as mitochondrion[20].
  • Twinkle mtDNA helicase's biological process is recorded as mitochondrial transcription[21].
  • Twinkle mtDNA helicase's biological process is recorded as DNA replication[22].
  • Twinkle mtDNA helicase's biological process is recorded as mitochondrion organization[23].
  • Twinkle mtDNA helicase's biological process is recorded as protein homooligomerization[24].
  • Twinkle mtDNA helicase's biological process is recorded as mitochondrial DNA replication[25].
  • Twinkle mtDNA helicase's biological process is recorded as protein hexamerization[26].
  • Twinkle mtDNA helicase's biological process is recorded as cellular response to glucose stimulus[27].

Why It Matters

Twinkle mtDNA helicase draws 11 Wikipedia views per month (protein category, ranking #152 of 987).[2] It is known by 10 alternative names across languages and contexts.[28]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . Q905695. Retrieved . wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . wikidata.org.
  5. [7] . wikidata.org.
  6. [8] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [9] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [10] . DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . TWINKLE Has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Twinkle mtDNA helicase. Retrieved May 3, 2026, from https://4ort.xyz/entity/twinkle-mtdna-helicase
MLA “Twinkle mtDNA helicase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/twinkle-mtdna-helicase.
BibTeX @misc{4ortxyz_twinkle-mtdna-helicase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Twinkle mtDNA helicase}}, year = {2026}, url = {https://4ort.xyz/entity/twinkle-mtdna-helicase}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Twinkle mtDNA helicase — https://4ort.xyz/entity/twinkle-mtdna-helicase (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/twinkle-mtdna-helicase · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 7w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from
    Subclass of protein
    Wikidata description mammalian protein found in Homo sapiens
    Encoded by TWNK
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 5.6.2.3, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.