Tumor protein p63

mammalian protein found in Rattus norvegicus

Protein protein Q28558521

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Tumor protein p63

Summary

Tumor protein p63 is a protein^[1].

Key Facts

Tumor protein p63's instance of is recorded as protein^[2].
Tumor protein p63's subclass of is recorded as protein^[3].
Tumor protein p63's UniProt protein ID is recorded as Q9JJP6^[4].
Tumor protein p63's part of is recorded as p53-like transcription factor, DNA-binding^[5].
Tumor protein p63's part of is recorded as p53/RUNT-type transcription factor, DNA-binding domain superfamily^[6].
Tumor protein p63's part of is recorded as p53-like tetramerisation domain superfamily^[7].
Tumor protein p63's part of is recorded as Tumour protein p63^[8].
Tumor protein p63's part of is recorded as Sterile alpha motif/pointed domain superfamily^[9].
Tumor protein p63's part of is recorded as Tumour protein p63, SAM domain, protein family^[10].
Tumor protein p63's part of is recorded as Sterile alpha motif domain, protein family^[11].
Tumor protein p63's part of is recorded as p53, tetramerisation domain, protein family^[12].
Tumor protein p63's part of is recorded as p53, DNA-binding domain, protein family^[13].
Tumor protein p63's has part is recorded as sterile alpha motif domain^[14].
Tumor protein p63's has part is recorded as p53, DNA-binding domain^[15].
Tumor protein p63's has part is recorded as p53, tetramerisation domain^[16].
Tumor protein p63's has part is recorded as tumour protein p63, SAM domain^[17].
Tumor protein p63's RefSeq protein ID is recorded as NP_001120811^[18].
Tumor protein p63's RefSeq protein ID is recorded as NP_001120813^[19].
Tumor protein p63's RefSeq protein ID is recorded as NP_001120814^[20].
Tumor protein p63's RefSeq protein ID is recorded as NP_001120815^[21].
Tumor protein p63's RefSeq protein ID is recorded as NP_001120816^[22].
Tumor protein p63's RefSeq protein ID is recorded as NP_062094^[23].
Tumor protein p63's RefSeq protein ID is recorded as XP_006248562^[24].
Tumor protein p63's RefSeq protein ID is recorded as XP_017453370^[25].
Tumor protein p63's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of p53-like transcription factor, DNA-binding, p53/RUNT-type transcription factor, DNA-binding domain superfamily, p53-like tetramerisation domain superfamily, Tumour protein p63, Sterile alpha motif/pointed domain superfamily, Tumour protein p63, SAM domain, protein family, Sterile alpha motif domain, protein family, p53, tetramerisation domain, protein family, p53, DNA-binding domain, protein family

Properties

Biological process negative regulation of transcription by RNA polymerase II, skeletal system development, establishment of planar polarity, morphogenesis of a polarized epithelium, hair follicle development, epithelial cell development, chromatin remodeling, regulation of transcription, DNA-templated, apoptotic process, Notch signaling pathway, multicellular organism development, spermatogenesis, pattern specification process, ectoderm and mesoderm interaction, ageing, cell population proliferation, epidermis development, animal organ morphogenesis, epidermal cell differentiation, proximal/distal pattern formation, multicellular organism aging, epidermal cell division, regulation of epidermal cell division, positive regulation of keratinocyte proliferation, cell differentiation, keratinocyte differentiation, embryonic limb morphogenesis, prostate gland development, epithelial cell differentiation, polarized epithelial cell differentiation, hair follicle morphogenesis, developmental process, negative regulation of intracellular estrogen receptor signaling pathway, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, post-anal tail morphogenesis, odontogenesis of dentin-containing tooth, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, regulation of cysteine-type endopeptidase activity involved in apoptotic process, skin morphogenesis, negative regulation of keratinocyte differentiation, positive regulation of osteoblast differentiation, positive regulation of Notch signaling pathway, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, sympathetic nervous system development, anatomical structure formation involved in morphogenesis, female genitalia morphogenesis, protein tetramerization, protein homotetramerization, neuron apoptotic process, cloacal septation, prostatic bud formation, squamous basal epithelial stem cell differentiation involved in prostate gland acinus development, establishment of skin barrier, skin epidermis development, positive regulation of somatic stem cell population maintenance, cranial skeletal system development, positive regulation of fibroblast apoptotic process, negative regulation of mesoderm development, positive regulation of apoptotic signaling pathway

Cell component nucleus, nucleoplasm, cytoplasm, rough endoplasmic reticulum, Golgi apparatus, cytosol, dendrite, protein-containing complex, neuron projection

Encoded by Tp63

Found in taxon brown rat

Has part(s) sterile alpha motif domain, p53, DNA-binding domain, p53, tetramerisation domain, tumour protein p63, SAM domain

Imported from wholeness_audit_2026-05-02

Molecular function DNA-binding transcription activator activity, RNA polymerase II-specific, p53 binding, DNA binding, chromatin binding, damaged DNA binding, double-stranded DNA binding, DNA-binding transcription factor activity, protein binding, protein domain specific binding, identical protein binding, sequence-specific DNA binding, metal ion binding, WW domain binding, MDM2/MDM4 family protein binding

External References (3)

Ensembl protein id ENSRNOP00000002636, ENSRNOP00000032308, ENSRNOP00000059178, ENSRNOP00000061884, ENSRNOP00000089600

Refseq protein id NP_001120811, NP_001120813, NP_001120814, NP_001120815, NP_001120816, NP_062094, XP_006248562, XP_017453370

Uniprot protein id Q9JJP6

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Tumor protein p63 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Tumor protein p63 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Tumor protein p63 — UniProt protein ID (P352): Q9JJP6. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Tumor protein p63 — part of (P361): p53-like transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Tumor protein p63 — part of (P361): p53/RUNT-type transcription factor, DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Tumor protein p63 — part of (P361): p53-like tetramerisation domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Tumor protein p63 — part of (P361): Tumour protein p63. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Tumor protein p63 — part of (P361): Sterile alpha motif/pointed domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Tumor protein p63 — part of (P361): Tumour protein p63, SAM domain, protein family. wikidata.org.
[11] ↑ Tumor protein p63 — part of (P361): Sterile alpha motif domain, protein family. wikidata.org.
[12] ↑ Tumor protein p63 — part of (P361): p53, tetramerisation domain, protein family. wikidata.org.
[13] ↑ Tumor protein p63 — part of (P361): p53, DNA-binding domain, protein family. wikidata.org.
[14] ↑ Tumor protein p63 — has part(s) (P527): sterile alpha motif domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Tumor protein p63 — has part(s) (P527): p53, DNA-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Tumor protein p63 — has part(s) (P527): p53, tetramerisation domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Tumor protein p63 — has part(s) (P527): tumour protein p63, SAM domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Tumor protein p63 — RefSeq protein ID (P637): NP_001120811. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Tumor protein p63 — RefSeq protein ID (P637): NP_001120813. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Tumor protein p63 — RefSeq protein ID (P637): NP_001120814. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Tumor protein p63 — RefSeq protein ID (P637): NP_001120815. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Tumor protein p63 — RefSeq protein ID (P637): NP_001120816. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Tumor protein p63 — RefSeq protein ID (P637): NP_062094. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Tumor protein p63 — RefSeq protein ID (P637): XP_006248562. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Tumor protein p63 — RefSeq protein ID (P637): XP_017453370. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Tumor protein p63 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Tumor protein p63 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Tumor protein p63. Retrieved May 3, 2026, from https://4ort.xyz/entity/tumor-protein-p63-q28558521

MLA

“Tumor protein p63.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/tumor-protein-p63-q28558521.

BibTeX

@misc{4ortxyz_tumor-protein-p63-q28558521_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Tumor protein p63}}, year = {2026}, url = {https://4ort.xyz/entity/tumor-protein-p63-q28558521}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Tumor protein p63 — https://4ort.xyz/entity/tumor-protein-p63-q28558521 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/tumor-protein-p63-q28558521 · Last refreshed: May 3, 2026