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trihexyphenidyl

chemical compound
Class type of: chemical compound Q2991856

Facts

14 properties
Instance of
type of chemical entity
Subclass of
chemical compound[5]
Has use
medication[6]
Canonical SMILES
C1CCC(CC1)C(CCN2CCCCC2)(C3=CC=CC=C3)O[3]
Chemical formula
C₂₀H₃₁NO[4]
Defined daily dose
+10[19]
LiverTox likelihood score
LiverTox toxicity likelihood category E*[20]
Mass
+301.241[11]
Medical condition treated
lingual-facial-buccal dyskinesia, Parkinson's disease, Parkinson's disease, neuroleptic extrapyramidal disorder[12][13][14][15]
Physically interacts with
Cholinergic receptor muscarinic 1[2]
Pregnancy category
US pregnancy category C[18]
Significant drug interaction
(±)-promethazine, (±)-promethazine, (±)-promethazine, (±)-promethazine[7][8][9][10]
Subject has role
antiparkinson, muscarinic antagonist[16][17]
Substance control status
Schedule 8 (Australia)[21]
🏷️ Also known as
en Trihexyphenidylum en Apo-trihex en Artane® en benzhexol en Benzhexol Hydrochloride en cyclodol en cyclodole en (RS)-1-cyclohexyl-1-phenyl-3-(1-piperidyl)propan-1-ol en Trihexifenidilo en trihexyphenidyl en Trihexyphenidyl en Trihexyphénidyle ar ثلاثي الهيكسيفينيديل es benzhexol fa تری هگزیفنیدیل fa تری هگزیفینیدیل fi bentsheksoli it Artane® it benzhexol it triesifenidile
🔖 Identifiers · 37
OpenAlex ID
C2779406339
ATC code
N04AA01
CAS Registry Number
144-11-6
ChEBI ID
9720
ChEMBL ID
CHEMBL1490
ChemSpider ID
5371
DSSTOX compound identifier
DTXCID703705
DSSTox substance ID
DTXSID4023705
DrugBank ID
DB00376
DrugCentral ID
2745
EC number
205-614-4
ECHA Substance Infocard ID
100.005.105
Show all 37 identifiers +25
Electronic Essential Medicines List medicine ID
410
Freebase ID
/m/0b8h0n
Guide to Pharmacology Ligand ID
7315
HSDB ID
3196
Human Metabolome Database ID
HMDB0014520
InChI
InChI=1S/C20H31NO/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2
InChIKey
HWHLPVGTWGOCJO-UHFFFAOYSA-N
KEGG ID
C07171, D08638
LiverTox ID
Trihexyphenidyl
MeSH descriptor ID
D014282
MeSH tree code
D03.383.621.900
MedlinePlus drug identifier
a682160
Microsoft Academic ID (discontinued)
2779406339
NDF-RT ID
N0000148044
NSC number
12268
Probes And Drugs ID
PD010217
PubChem CID
5572
RxNorm CUI
10811
SPLASH
splash10-0002-9200000000-2092a098302f5e63b76c
Store medisinske leksikon ID
benzheksol
SureChEMBL ID
34645
UMLS CUI
C0041009
UNII
6RC5V8B7PO
UniChem compound ID
251431
WikiProjectMed ID
Trihexyphenidyl

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections
Significant drug interaction 4
(±)-promethazine, (±)-promethazine, (±)-promethazine, (±)-promethazine
← Significant drug interaction 4
(±)-promethazine, (±)-promethazine, (±)-promethazine, (±)-promethazine
Medical condition treated 2
Parkinson's disease, Parkinson's disease
Subject has role 2
antiparkinson, muscarinic antagonist
← Drug or therapy used for treatment 2
Parkinson's disease, Parkinson's disease
Belongs to 1
World Health Organization Model List of Essential Medicines
Has use 1
medication
Subclass of 1
chemical compound
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Summary

trihexyphenidyl is a type of chemical entity[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . wikidata.org.
  2. [3] ↑ . wikidata.org.
  3. [4] ↑ . wikidata.org.
  4. [5] ↑ . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . wikidata.org.
  7. [8] ↑ . wikidata.org.
  8. [9] ↑ . wikidata.org.
  9. [10] ↑ . wikidata.org.
  10. [11] ↑ . wikidata.org.
  11. [12] ↑ . wikidata.org.
  12. [13] ↑ . wikidata.org.
  13. [14] ↑ . wikidata.org.
  14. [15] ↑ . wikidata.org.
  15. [16] ↑ . wikidata.org.
  16. [17] ↑ . wikidata.org.
  17. [18] ↑ . wikidata.org.
  18. [19] ↑ . wikidata.org.
  19. [20] ↑ . wikidata.org.
  20. [21] ↑ . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). trihexyphenidyl. Retrieved November 6, 2026, from https://4ort.xyz/entity/trihexyphenidyl
MLA “trihexyphenidyl.” 4ort.xyz Knowledge Graph, 4ort.xyz, 6 Nov. 2026, https://4ort.xyz/entity/trihexyphenidyl.
BibTeX @misc{4ortxyz_trihexyphenidyl_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{trihexyphenidyl}}, year = {2026}, url = {https://4ort.xyz/entity/trihexyphenidyl}, note = {Accessed: 2026-11-06}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): trihexyphenidyl — https://4ort.xyz/entity/trihexyphenidyl (retrieved 2026-11-06)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 9w ago · Carn · 2026-08-31 view diff on Wikidata ↗
    LiverTox likelihood score → LiverTox toxicity likelihood category E*
    Subclass of → chemical compound
    Has use → medication
    Subject has role → antiparkinson, muscarinic antagonist
    + 8 other properties edited (see Wikidata diff for full list)
    "Created claim: Substance control status: Schedule 8 (Australia), batch #269907"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.