Trefoil factor 2

mouse protein (annotated by UniProtKB/Swiss-Prot Q03404)
Protein protein Q21991249
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Trefoil factor 2

Summary

Trefoil factor 2 is a protein[1].

Key Facts

  • Trefoil factor 2's instance of is recorded as protein[2].
  • Trefoil factor 2's UniProt protein ID is recorded as Q03404[3].
  • Trefoil factor 2's part of is recorded as P-type trefoil, chordata[4].
  • Trefoil factor 2's part of is recorded as P-type trefoil domain, protein family[5].
  • Trefoil factor 2's part of is recorded as P-type trefoil, conserved site, protein family[6].
  • Trefoil factor 2's has part is recorded as P-type trefoil, conserved site[7].
  • Trefoil factor 2's has part is recorded as P-type trefoil domain[8].
  • Trefoil factor 2's PDB structure ID is recorded as 2DYZ[9].
  • Trefoil factor 2's PDB structure ID is recorded as 2DZ0[10].
  • Trefoil factor 2's PDB structure ID is recorded as 2DZ1[11].
  • Trefoil factor 2's molecular function is recorded as CXCR4 chemokine receptor binding[12].
  • Trefoil factor 2's molecular function is recorded as CXCR4 chemokine receptor binding[13].
  • Trefoil factor 2's cell component is recorded as extracellular region[14].
  • Trefoil factor 2's cell component is recorded as intracellular anatomical structure[15].
  • Trefoil factor 2's cell component is recorded as extracellular space[16].
  • Trefoil factor 2's cell component is recorded as extracellular space[17].
  • Trefoil factor 2's biological process is recorded as chemokine-mediated signaling pathway[18].
  • Trefoil factor 2's biological process is recorded as negative regulation of macrophage activation[19].
  • Trefoil factor 2's biological process is recorded as negative regulation of gastric acid secretion[20].
  • Trefoil factor 2's biological process is recorded as regulation of cell migration[21].
  • Trefoil factor 2's biological process is recorded as negative regulation of inflammatory response[22].
  • Trefoil factor 2's biological process is recorded as positive regulation of cell population proliferation[23].
  • Trefoil factor 2's biological process is recorded as calcium-mediated signaling[24].
  • Trefoil factor 2's biological process is recorded as positive regulation of ERK1 and ERK2 cascade[25].
  • Trefoil factor 2's biological process is recorded as wound healing[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . Swiss-Prot. Retrieved . uniprot.org. Provenance: wikidata.org.
  9. [10] . Swiss-Prot. Retrieved . uniprot.org. Provenance: wikidata.org.
  10. [11] . Swiss-Prot. Retrieved . uniprot.org. Provenance: wikidata.org.
  11. [12] . Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Trefoil factor 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/trefoil-factor-2-q21991249
MLA “Trefoil factor 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/trefoil-factor-2-q21991249.
BibTeX @misc{4ortxyz_trefoil-factor-2-q21991249_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Trefoil factor 2}}, year = {2026}, url = {https://4ort.xyz/entity/trefoil-factor-2-q21991249}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Trefoil factor 2 — https://4ort.xyz/entity/trefoil-factor-2-q21991249 (retrieved 2026-05-03)

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