Transcription factor AP-4

mammalian protein found in Rattus norvegicus

Protein protein Q29523630

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Summary

Transcription factor AP-4 is a protein^[1].

Key Facts

Transcription factor AP-4's instance of is recorded as protein^[2].
Transcription factor AP-4's UniProt protein ID is recorded as D3ZJT6^[3].
Transcription factor AP-4's part of is recorded as Helix-loop-helix DNA-binding domain superfamily^[4].
Transcription factor AP-4's part of is recorded as Myc-type, basic helix-loop-helix (bHLH) domain, protein family^[5].
Transcription factor AP-4's has part is recorded as Myc-type, basic helix-loop-helix (bHLH) domain^[6].
Transcription factor AP-4's RefSeq protein ID is recorded as NP_001101737^[7].
Transcription factor AP-4's RefSeq protein ID is recorded as XP_006245880^[8].
Transcription factor AP-4's RefSeq protein ID is recorded as XP_006245881^[9].
Transcription factor AP-4's RefSeq protein ID is recorded as XP_006245884^[10].
Transcription factor AP-4's RefSeq protein ID is recorded as XP_006245885^[11].
Transcription factor AP-4's RefSeq protein ID is recorded as XP_017452854^[12].
Transcription factor AP-4's RefSeq protein ID is recorded as XP_038942195^[13].
Transcription factor AP-4's RefSeq protein ID is recorded as XP_038942196^[14].
Transcription factor AP-4's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding^[15].
Transcription factor AP-4's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[16].
Transcription factor AP-4's molecular function is recorded as DNA binding^[17].
Transcription factor AP-4's molecular function is recorded as DNA-binding transcription factor activity^[18].
Transcription factor AP-4's molecular function is recorded as transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding^[19].
Transcription factor AP-4's molecular function is recorded as protein homodimerization activity^[20].
Transcription factor AP-4's molecular function is recorded as histone deacetylase binding^[21].
Transcription factor AP-4's molecular function is recorded as sequence-specific DNA binding^[22].
Transcription factor AP-4's molecular function is recorded as protein dimerization activity^[23].
Transcription factor AP-4's molecular function is recorded as E-box binding^[24].
Transcription factor AP-4's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[25].
Transcription factor AP-4's cell component is recorded as nucleus^[26].

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Quick Facts

Instance of protein

Part of Helix-loop-helix DNA-binding domain superfamily, Myc-type, basic helix-loop-helix (bHLH) domain, protein family

Properties

Biological process regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, negative regulation of cell population proliferation, negative regulation of gene expression, positive regulation of apoptotic process, negative regulation of DNA binding, negative regulation by host of viral transcription, positive regulation by host of viral transcription, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, cellular response to dexamethasone stimulus, regulation of mitotic cell cycle phase transition, positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, protein-containing complex assembly

Cell component nucleus, mitochondrion, transcription repressor complex

Encoded by Tfap4

Found in taxon brown rat

Has part(s) Myc-type, basic helix-loop-helix (bHLH) domain

Imported from wholeness_audit_2026-05-02

Molecular function RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA binding, DNA-binding transcription factor activity, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, protein homodimerization activity, histone deacetylase binding, sequence-specific DNA binding, protein dimerization activity, E-box binding, DNA-binding transcription factor activity, RNA polymerase II-specific

External References (3)

Ensembl protein id ENSRNOP00000006979

Refseq protein id NP_001101737, XP_006245880, XP_006245881, XP_006245884, XP_006245885, XP_017452854, XP_038942195, XP_038942196

Uniprot protein id D3ZJT6

🏷️ Also known as

en Tfap4 en transcription factor AP4 en Transcription factor AP-4 en transcription factor AP-4 (activating enhancer binding protein 4)

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Transcription factor AP-4 — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Transcription factor AP-4 — UniProt protein ID (P352): D3ZJT6. UniProt. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Transcription factor AP-4 — part of (P361): Helix-loop-helix DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Transcription factor AP-4 — part of (P361): Myc-type, basic helix-loop-helix (bHLH) domain, protein family. wikidata.org.
[6] ↑ Transcription factor AP-4 — has part(s) (P527): Myc-type, basic helix-loop-helix (bHLH) domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Transcription factor AP-4 — RefSeq protein ID (P637): NP_001101737. Q20641742. Retrieved 2022-03-20. wikidata.org.
[8] ↑ Transcription factor AP-4 — RefSeq protein ID (P637): XP_006245880. Q20641742. Retrieved 2022-03-20. wikidata.org.
[9] ↑ Transcription factor AP-4 — RefSeq protein ID (P637): XP_006245881. Q20641742. Retrieved 2022-03-20. wikidata.org.
[10] ↑ Transcription factor AP-4 — RefSeq protein ID (P637): XP_006245884. Q20641742. Retrieved 2022-03-20. wikidata.org.
[11] ↑ Transcription factor AP-4 — RefSeq protein ID (P637): XP_006245885. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ Transcription factor AP-4 — RefSeq protein ID (P637): XP_017452854. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ Transcription factor AP-4 — RefSeq protein ID (P637): XP_038942195. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ Transcription factor AP-4 — RefSeq protein ID (P637): XP_038942196. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ Transcription factor AP-4 — molecular function (P680): RNA polymerase II cis-regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Transcription factor AP-4 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Transcription factor AP-4 — molecular function (P680): DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Transcription factor AP-4 — molecular function (P680): DNA-binding transcription factor activity. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Transcription factor AP-4 — molecular function (P680): transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Transcription factor AP-4 — molecular function (P680): protein homodimerization activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Transcription factor AP-4 — molecular function (P680): histone deacetylase binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Transcription factor AP-4 — molecular function (P680): sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Transcription factor AP-4 — molecular function (P680): protein dimerization activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Transcription factor AP-4 — molecular function (P680): E-box binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Transcription factor AP-4 — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Transcription factor AP-4 — cell component (P681): nucleus. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Transcription factor AP-4 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“Transcription factor AP-4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/transcription-factor-ap-4-q29523630.

BibTeX

@misc{4ortxyz_transcription-factor-ap-4-q29523630_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Transcription factor AP-4}}, year = {2026}, url = {https://4ort.xyz/entity/transcription-factor-ap-4-q29523630}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Transcription factor AP-4 — https://4ort.xyz/entity/transcription-factor-ap-4-q29523630 (retrieved 2026-05-03)

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