Transcription factor AP-2 beta

mammalian protein found in Homo sapiens

Protein protein Q21202951

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Transcription factor AP-2 beta

Summary

Transcription factor AP-2 beta is a protein^[1].

Key Facts

Transcription factor AP-2 beta's instance of is recorded as protein^[2].
Transcription factor AP-2 beta's subclass of is recorded as protein^[3].
Transcription factor AP-2 beta's UniProt protein ID is recorded as Adolf Dyroff^[4].
Transcription factor AP-2 beta's part of is recorded as Transcription factor AP-2 beta^[5].
Transcription factor AP-2 beta's part of is recorded as Transcription factor AP-2, C-terminal domain, protein family^[6].
Transcription factor AP-2 beta's has part is recorded as Transcription factor AP-2, C-terminal^[7].
Transcription factor AP-2 beta's RefSeq protein ID is recorded as NP_003212^[8].
Transcription factor AP-2 beta's RefSeq protein ID is recorded as XP_011513139^[9].
Transcription factor AP-2 beta's RefSeq protein ID is recorded as XP_016866722^[10].
Transcription factor AP-2 beta's RefSeq protein ID is recorded as XP_016866723^[11].
Transcription factor AP-2 beta's RefSeq protein ID is recorded as XP_016866724^[12].
Transcription factor AP-2 beta's molecular function is recorded as DNA binding^[13].
Transcription factor AP-2 beta's molecular function is recorded as transcription coactivator activity^[14].
Transcription factor AP-2 beta's molecular function is recorded as sequence-specific DNA binding^[15].
Transcription factor AP-2 beta's molecular function is recorded as transcription corepressor activity^[16].
Transcription factor AP-2 beta's molecular function is recorded as protein dimerization activity^[17].
Transcription factor AP-2 beta's molecular function is recorded as protein homodimerization activity^[18].
Transcription factor AP-2 beta's molecular function is recorded as transcription corepressor activity^[19].
Transcription factor AP-2 beta's molecular function is recorded as DNA-binding transcription factor activity^[20].
Transcription factor AP-2 beta's molecular function is recorded as transcription coactivator activity^[21].
Transcription factor AP-2 beta's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[22].
Transcription factor AP-2 beta's molecular function is recorded as chromatin binding^[23].
Transcription factor AP-2 beta's molecular function is recorded as RNA polymerase II general transcription initiation factor activity^[24].
Transcription factor AP-2 beta's molecular function is recorded as cysteine-type endopeptidase inhibitor activity involved in apoptotic process^[25].
Transcription factor AP-2 beta's molecular function is recorded as protein binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Transcription factor AP-2 beta, Transcription factor AP-2, C-terminal domain, protein family

Properties

Biological process negative regulation of neuron apoptotic process, forelimb morphogenesis, collecting duct development, cellular urea homeostasis, regulation of transcription, DNA-templated, sympathetic nervous system development, retina layer formation, positive regulation of urine volume, glucose homeostasis, calcium ion homeostasis, distal tubule development, kidney development, regulation of insulin secretion, phosphate ion homeostasis, cellular creatinine homeostasis, negative regulation of apoptotic process, transcription by RNA polymerase II, metanephric nephron development, aorta morphogenesis, magnesium ion homeostasis, hindlimb morphogenesis, transcription, DNA-templated, response to lithium ion, regulation of BMP signaling pathway, positive regulation of transcription, DNA-templated, positive regulation of neuron apoptotic process, cellular ammonium homeostasis, potassium ion homeostasis, positive regulation of cell population proliferation, renal water homeostasis, glucose metabolic process, sensory organ development, regulation of cell differentiation, sodium ion homeostasis, negative regulation of transcription, DNA-templated, fat cell differentiation, ductus arteriosus closure, negative regulation of cell population proliferation, skin development, apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of transcription by RNA polymerase II, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II

Cell component nucleus, nucleoplasm, nucleus

Encoded by TFAP2B

Found in taxon Homo sapiens

Has part(s) Transcription factor AP-2, C-terminal

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, transcription coactivator activity, sequence-specific DNA binding, transcription corepressor activity, protein dimerization activity, protein homodimerization activity, transcription corepressor activity, DNA-binding transcription factor activity, transcription coactivator activity, DNA-binding transcription activator activity, RNA polymerase II-specific, chromatin binding, RNA polymerase II general transcription initiation factor activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, cis-regulatory region sequence-specific DNA binding, protein heterodimerization activity, RNA polymerase II core promoter sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription coactivator activity, transcription corepressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific

External References (3)

Ensembl protein id ENSP00000377265, ENSP00000342252

Refseq protein id NP_003212, XP_011513139, XP_016866722, XP_016866723, XP_016866724

Uniprot protein id Adolf Dyroff

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Transcription factor AP-2 beta — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Transcription factor AP-2 beta — subclass of (P279): protein. Q905695. Retrieved 2016-12-01. wikidata.org.
[4] ↑ Transcription factor AP-2 beta — UniProt protein ID (P352): Adolf Dyroff. Q905695. Retrieved 2019-11-13. wikidata.org.
[5] ↑ Transcription factor AP-2 beta — part of (P361): Transcription factor AP-2 beta. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Transcription factor AP-2 beta — part of (P361): Transcription factor AP-2, C-terminal domain, protein family. wikidata.org.
[7] ↑ Transcription factor AP-2 beta — has part(s) (P527): Transcription factor AP-2, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Transcription factor AP-2 beta — RefSeq protein ID (P637): NP_003212. Q20641742. Retrieved 2020-05-30. wikidata.org.
[9] ↑ Transcription factor AP-2 beta — RefSeq protein ID (P637): XP_011513139. Q20641742. Retrieved 2020-05-30. wikidata.org.
[10] ↑ Transcription factor AP-2 beta — RefSeq protein ID (P637): XP_016866722. Q20641742. Retrieved 2020-05-30. wikidata.org.
[11] ↑ Transcription factor AP-2 beta — RefSeq protein ID (P637): XP_016866723. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ Transcription factor AP-2 beta — RefSeq protein ID (P637): XP_016866724. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ Transcription factor AP-2 beta — molecular function (P680): DNA binding. Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Transcription factor AP-2 beta — molecular function (P680): transcription coactivator activity. GOA. Retrieved 2018-03-27. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Transcription factor AP-2 beta — molecular function (P680): sequence-specific DNA binding. Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Transcription factor AP-2 beta — molecular function (P680): transcription corepressor activity. GOA. Retrieved 2018-03-27. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Transcription factor AP-2 beta — molecular function (P680): protein dimerization activity. Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Transcription factor AP-2 beta — molecular function (P680): protein homodimerization activity. Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Transcription factor AP-2 beta — molecular function (P680): transcription corepressor activity. Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression. Retrieved 2018-03-27. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Transcription factor AP-2 beta — molecular function (P680): DNA-binding transcription factor activity. Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Transcription factor AP-2 beta — molecular function (P680): transcription coactivator activity. GOA. Retrieved 2018-03-27. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Transcription factor AP-2 beta — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Transcription factor AP-2 beta — molecular function (P680): chromatin binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Transcription factor AP-2 beta — molecular function (P680): RNA polymerase II general transcription initiation factor activity. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Transcription factor AP-2 beta — molecular function (P680): cysteine-type endopeptidase inhibitor activity involved in apoptotic process. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Transcription factor AP-2 beta — molecular function (P680): protein binding. Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Transcription factor AP-2 beta is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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