Transcription factor 3
mammalian protein found in Mus musculus
Facts
9 properties- Instance of
- protein
- Part of
- Helix-loop-helix DNA-binding domain superfamily, Myc-type, basic helix-loop-helix (bHLH) domain, protein family[3][4]
- Biological process
- cell differentiation, regulation of transcription, DNA-templated, T cell differentiation in thymus, cell development, lymphocyte differentiation, regulation of transcription by RNA polymerase II, protein stabilization, positive regulation of DNA-binding transcription factor activity, negative regulation of transcription by RNA polymerase II, transcription, DNA-templated, nervous system development, positive regulation of transcription, DNA-templated, response to lipopolysaccharide, gastrulation, positive regulation of neuron differentiation, histone H3 acetylation, histone H4 acetylation, immunoglobulin V(D)J recombination, Peyer's patch development, positive regulation of transcription by RNA polymerase II, natural killer cell differentiation, transcription by RNA polymerase II, B cell lineage commitment, positive regulation of B cell proliferation, positive regulation of cell cycle, regulation of G1/S transition of mitotic cell cycle, positive regulation of gene expression, transcription by RNA polymerase II, erythrocyte differentiation, negative regulation of erythrocyte differentiation, positive regulation of protein tyrosine kinase activity, positive regulation of signaling receptor activity, B cell lineage commitment, transcription, DNA-templated, regulation of transcription, DNA-templated, positive regulation of B cell proliferation, immunoglobulin V(D)J recombination, positive regulation of neuron differentiation, positive regulation of cell cycle, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, regulation of G1/S transition of mitotic cell cycle
- Cell component
- cytoplasm, transcription regulator complex, nucleus, nuclear speck, RNA polymerase II transcription regulator complex, nucleoplasm, protein-containing complex, nucleus, transcription regulator complex, cytoplasm, protein-containing complex
- Encoded by
- Tcf3
- Found in taxon
- house mouse
- Has part(s)
- Myc-type, basic helix-loop-helix (bHLH) domain[5]
- Molecular function
- RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA binding, protein dimerization activity, protein homodimerization activity, DNA-binding transcription factor activity, mitogen-activated protein kinase kinase kinase binding, vitamin D response element binding, transcription coactivator activity, DNA-binding transcription activator activity, RNA polymerase II-specific, transcription factor binding, chromatin binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, bHLH transcription factor binding, E-box binding, DNA-binding transcription activator activity, RNA polymerase II-specific, protein binding, protein heterodimerization activity, sequence-specific DNA binding, PDZ domain binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, transcription factor binding, protein homodimerization activity, sequence-specific DNA binding, protein heterodimerization activity
🏷️ Also known as
en immunoglobulin enhancer-binding factor E12/E47
en Tcf3
en TCF-3
en Transcription factor 3
en transcription factor A1
en transcription factor E2a
en transcription factor E2-alpha
🔖 Identifiers · 4
- Ensembl protein ID
- ENSMUSP00000100982, ENSMUSP00000100983, ENSMUSP00000020377, ENSMUSP00000020379, ENSMUSP00000100976, ENSMUSP00000100977, ENSMUSP00000100978, ENSMUSP00000100979, ENSMUSP00000100980, ENSMUSP00000100981, ENSMUSP00000120303, ENSMUSP00000121172
- PDB structure ID
- 2QL2
- RefSeq protein ID
- NP_001157619, NP_001157620, NP_001157621, NP_001157622, NP_001157623, NP_001157624, NP_001157625, NP_035678, XP_017169361, XP_030100855, NP_001365832, NP_001365833, NP_001365834, NP_001365837, NP_001365839, NP_001365841, NP_001365842, NP_001365843
- UniProt protein ID
- P15806
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Summary
Transcription factor 3 is a protein[1].