Transcription factor 3

mammalian protein found in Mus musculus

Protein protein Q21494515

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Transcription factor 3

Summary

Transcription factor 3 is a protein^[1].

Key Facts

Transcription factor 3's instance of is recorded as protein^[2].
Transcription factor 3's subclass of is recorded as protein^[3].
Transcription factor 3's UniProt protein ID is recorded as P15806^[4].
Transcription factor 3's part of is recorded as Helix-loop-helix DNA-binding domain superfamily^[5].
Transcription factor 3's part of is recorded as Myc-type, basic helix-loop-helix (bHLH) domain, protein family^[6].
Transcription factor 3's has part is recorded as Myc-type, basic helix-loop-helix (bHLH) domain^[7].
Transcription factor 3's RefSeq protein ID is recorded as NP_001157619^[8].
Transcription factor 3's RefSeq protein ID is recorded as NP_001157620^[9].
Transcription factor 3's RefSeq protein ID is recorded as NP_001157621^[10].
Transcription factor 3's RefSeq protein ID is recorded as NP_001157622^[11].
Transcription factor 3's RefSeq protein ID is recorded as NP_001157623^[12].
Transcription factor 3's RefSeq protein ID is recorded as NP_001157624^[13].
Transcription factor 3's RefSeq protein ID is recorded as NP_001157625^[14].
Transcription factor 3's RefSeq protein ID is recorded as NP_035678^[15].
Transcription factor 3's RefSeq protein ID is recorded as XP_017169361^[16].
Transcription factor 3's RefSeq protein ID is recorded as XP_030100855^[17].
Transcription factor 3's RefSeq protein ID is recorded as NP_001365832^[18].
Transcription factor 3's RefSeq protein ID is recorded as NP_001365833^[19].
Transcription factor 3's RefSeq protein ID is recorded as NP_001365834^[20].
Transcription factor 3's RefSeq protein ID is recorded as NP_001365837^[21].
Transcription factor 3's RefSeq protein ID is recorded as NP_001365839^[22].
Transcription factor 3's RefSeq protein ID is recorded as NP_001365841^[23].
Transcription factor 3's RefSeq protein ID is recorded as NP_001365842^[24].
Transcription factor 3's RefSeq protein ID is recorded as NP_001365843^[25].
Transcription factor 3's PDB structure ID is recorded as 2QL2^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Helix-loop-helix DNA-binding domain superfamily, Myc-type, basic helix-loop-helix (bHLH) domain, protein family

Properties

Biological process cell differentiation, regulation of transcription, DNA-templated, T cell differentiation in thymus, cell development, lymphocyte differentiation, regulation of transcription by RNA polymerase II, protein stabilization, positive regulation of DNA-binding transcription factor activity, negative regulation of transcription by RNA polymerase II, transcription, DNA-templated, nervous system development, positive regulation of transcription, DNA-templated, response to lipopolysaccharide, gastrulation, positive regulation of neuron differentiation, histone H3 acetylation, histone H4 acetylation, immunoglobulin V(D)J recombination, Peyer's patch development, positive regulation of transcription by RNA polymerase II, natural killer cell differentiation, transcription by RNA polymerase II, B cell lineage commitment, positive regulation of B cell proliferation, positive regulation of cell cycle, regulation of G1/S transition of mitotic cell cycle, positive regulation of gene expression, transcription by RNA polymerase II, erythrocyte differentiation, negative regulation of erythrocyte differentiation, positive regulation of protein tyrosine kinase activity, positive regulation of signaling receptor activity, B cell lineage commitment, transcription, DNA-templated, regulation of transcription, DNA-templated, positive regulation of B cell proliferation, immunoglobulin V(D)J recombination, positive regulation of neuron differentiation, positive regulation of cell cycle, positive regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, regulation of G1/S transition of mitotic cell cycle

Cell component cytoplasm, transcription regulator complex, nucleus, nuclear speck, RNA polymerase II transcription regulator complex, nucleoplasm, protein-containing complex, nucleus, transcription regulator complex, cytoplasm, protein-containing complex

Encoded by Tcf3

Found in taxon house mouse

Has part(s) Myc-type, basic helix-loop-helix (bHLH) domain

Imported from wholeness_audit_2026-05-02

Molecular function RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA binding, protein dimerization activity, protein homodimerization activity, DNA-binding transcription factor activity, mitogen-activated protein kinase kinase kinase binding, vitamin D response element binding, transcription coactivator activity, DNA-binding transcription activator activity, RNA polymerase II-specific, transcription factor binding, chromatin binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, bHLH transcription factor binding, E-box binding, DNA-binding transcription activator activity, RNA polymerase II-specific, protein binding, protein heterodimerization activity, sequence-specific DNA binding, PDZ domain binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, transcription factor binding, protein homodimerization activity, sequence-specific DNA binding, protein heterodimerization activity

External References (4)

Ensembl protein id ENSMUSP00000100982, ENSMUSP00000100983, ENSMUSP00000020377, ENSMUSP00000020379, ENSMUSP00000100976, ENSMUSP00000100977, ENSMUSP00000100978, ENSMUSP00000100979, ENSMUSP00000100980, ENSMUSP00000100981, ENSMUSP00000120303, ENSMUSP00000121172

Pdb structure id 2QL2

Refseq protein id NP_001157619, NP_001157620, NP_001157621, NP_001157622, NP_001157623, NP_001157624, NP_001157625, NP_035678, XP_017169361, XP_030100855, NP_001365832, NP_001365833, NP_001365834, NP_001365837, NP_001365839, NP_001365841, NP_001365842, NP_001365843

Uniprot protein id P15806

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Transcription factor 3 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Transcription factor 3 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Transcription factor 3 — UniProt protein ID (P352): P15806. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Transcription factor 3 — part of (P361): Helix-loop-helix DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Transcription factor 3 — part of (P361): Myc-type, basic helix-loop-helix (bHLH) domain, protein family. wikidata.org.
[7] ↑ Transcription factor 3 — has part(s) (P527): Myc-type, basic helix-loop-helix (bHLH) domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001157619. Q20641742. Retrieved 2022-03-20. wikidata.org.
[9] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001157620. Q20641742. Retrieved 2022-03-20. wikidata.org.
[10] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001157621. Q20641742. Retrieved 2022-03-20. wikidata.org.
[11] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001157622. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001157623. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001157624. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001157625. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_035678. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Transcription factor 3 — RefSeq protein ID (P637): XP_017169361. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Transcription factor 3 — RefSeq protein ID (P637): XP_030100855. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001365832. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001365833. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001365834. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001365837. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001365839. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001365841. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001365842. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Transcription factor 3 — RefSeq protein ID (P637): NP_001365843. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Transcription factor 3 — PDB structure ID (P638): 2QL2. Q905695. Retrieved 2016-08-09. wikidata.org.

Class ancestry

[1] ↑ Transcription factor 3 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Transcription factor 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/transcription-factor-3

MLA

“Transcription factor 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/transcription-factor-3.

BibTeX

@misc{4ortxyz_transcription-factor-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Transcription factor 3}}, year = {2026}, url = {https://4ort.xyz/entity/transcription-factor-3}, note = {Accessed: 2026-05-03}}

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According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Transcription factor 3 — https://4ort.xyz/entity/transcription-factor-3 (retrieved 2026-05-03)

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