Transcription factor 12
mammalian protein found in Homo sapiens
Facts
11 properties- Instance of
- protein
- Part of
- Helix-loop-helix DNA-binding domain superfamily, Myc-type, basic helix-loop-helix (bHLH) domain, protein family[4][5]
- Biological process
- cell differentiation, regulation of transcription, DNA-templated, regulation of transcription by RNA polymerase II, muscle organ development, transcription, DNA-templated, nervous system development, multicellular organism development, positive regulation of transcription, DNA-templated, positive regulation of gene expression, positive regulation of neuron differentiation, immune response, positive regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, regulation of hematopoietic stem cell differentiation, positive regulation of transcription by RNA polymerase II
- Cell component
- cytoplasm, transcription regulator complex, RNA polymerase II transcription regulator complex, nucleus, nuclear speck, intracellular membrane-bounded organelle, nucleoplasm, nucleus, transcription regulator complex
- Encoded by
- TCF12
- Found in taxon
- Homo sapiens
- Has part(s)
- Myc-type, basic helix-loop-helix (bHLH) domain[6]
- Imported from
- wholeness_audit_2026-05-02
- Molecular function
- DNA binding, protein dimerization activity, protein homodimerization activity, DNA-binding transcription factor activity, HMG box domain binding, DNA-binding transcription activator activity, RNA polymerase II-specific, transcription factor binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, bHLH transcription factor binding, E-box binding, protein binding, protein heterodimerization activity, SMAD binding, cAMP response element binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, bHLH transcription factor binding
- Physically interacts with
- Viroporin 3a[2]
🏷️ Also known as
en bHLHb20
en class B basic helix-loop-helix protein 20
en DNA-binding protein HTF4
en E-box-binding protein
en helix-loop-helix transcription factor 4
en TCF12
en Transcription factor 12
en transcription factor HTF-4
🔖 Identifiers · 4
- Ensembl protein ID
- ENSP00000267811, ENSP00000331057, ENSP00000342459, ENSP00000388940, ENSP00000444696, ENSP00000453737, ENSP00000440017, ENSP00000453264, ENSP00000453653, ENSP00000453876, ENSP00000454102, ENSP00000454109, ENSP00000454823, ENSP00000456280
- RefSeq protein ID
- NP_001293148, NP_001293149, NP_001309080, NP_001309081, NP_001309083, NP_001309085, NP_001309086, NP_001309087, NP_001309088, NP_001309090, NP_001309091, NP_001309093, NP_001309094, NP_003196, NP_996919, NP_996920, NP_996921, NP_996923, XP_011520261, XP_011520262, XP_011520263, XP_011520264, XP_011520265, XP_011520267, XP_011520268, XP_011520269, XP_011520271, XP_016878009
- UniProt protein ID
- Thomas Ahrens
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Summary
Transcription factor 12 is a protein[1].