tolvaptan

selective, competitive vasopressin receptor 2 antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone
ChemicalSubstance type_of_chemical_entity Q426132
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tolvaptan

Summary

tolvaptan is a type of chemical entity[1]. tolvaptan ranks in the top 5% of type_of_chemical_entity entities by monthly Wikipedia readership (96 views/month).[2]

Key Facts

  • tolvaptan's instance of is recorded as type of chemical entity[3].
  • tolvaptan's chemical structure is recorded as Tolvaptan.svg[4].
  • tolvaptan's physically interacts with is recorded as Arginine vasopressin receptor 1A[5].
  • tolvaptan's physically interacts with is recorded as Arginine vasopressin receptor 2[6].
  • tolvaptan's CAS Registry Number is recorded as 150683-30-0[7].
  • tolvaptan's EC number is recorded as 691-537-5[8].
  • tolvaptan's canonical SMILES is recorded as CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C[9].
  • tolvaptan's InChI is recorded as InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)[10].
  • tolvaptan's InChIKey is recorded as GYHCTFXIZSNGJT-UHFFFAOYSA-N[11].
  • tolvaptan's ATC code is recorded as C03XA01[12].
  • tolvaptan's chemical formula is recorded as C₂₆H₂₅ClN₂O₃[13].
  • tolvaptan's subclass of is recorded as chemical compound[14].
  • tolvaptan's has use is recorded as medication[15].
  • tolvaptan's Commons category is recorded as Tolvaptan[16].
  • tolvaptan's MeSH descriptor ID is recorded as D000077602[17].
  • tolvaptan's ChEMBL ID is recorded as CHEMBL344159[18].
  • tolvaptan's Guide to Pharmacology Ligand ID is recorded as 2226[19].
  • tolvaptan's Freebase ID is recorded as /m/026ljpf[20].
  • tolvaptan's UNII is recorded as 21G72T1950[21].
  • tolvaptan's ChemSpider ID is recorded as 187438[22].
  • tolvaptan's PubChem CID is recorded as 216237[23].
  • tolvaptan's KEGG ID is recorded as D01213[24].
  • tolvaptan's MeSH tree code is recorded as D03.633.100.079.875[25].
  • tolvaptan's ChEBI ID is recorded as 32246[26].
  • tolvaptan's HSDB ID is recorded as 8196[27].

Why It Matters

tolvaptan ranks in the top 5% of type_of_chemical_entity entities by monthly Wikipedia readership (96 views/month).[2] tolvaptan has Wikipedia articles in 13 language editions, a strong signal of global cultural recognition.[28] tolvaptan is known by 4 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . wikidata.org.
  2. [4] . wikidata.org.
  3. [5] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [6] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  5. [7] . Global Substance Registration System. Retrieved . commonchemistry.cas.org. Provenance: wikidata.org.
  6. [8] . ECHA Substance Infocard database. Retrieved . wikidata.org.
  7. [9] . PubChem. Retrieved . wikidata.org.
  8. [10] . PubChem. Retrieved . wikidata.org.
  9. [11] . PubChem. Retrieved . wikidata.org.
  10. [12] . DrugBank. wikidata.org.
  11. [13] . PubChem. Retrieved . wikidata.org.
  12. [14] . wikidata.org.
  13. [15] . wikidata.org.
  14. [16] . wikidata.org.
  15. [17] . wikidata.org.
  16. [18] . ChEMBL. Retrieved . wikidata.org.
  17. [19] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  18. [20] . Freebase Data Dumps. wikidata.org.
  19. [21] . Global Substance Registration System. Retrieved . wikidata.org.
  20. [22] . Q2311683. Retrieved . wikidata.org.
  21. [23] . PubChem. Retrieved . wikidata.org.
  22. [24] . ChEMBL. Retrieved . wikidata.org.
  23. [25] . wikidata.org.
  24. [26] . ChEBI release 2019-10-02. wikidata.org.
  25. [27] . Hazardous Substances Data Bank. Retrieved . wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). tolvaptan. Retrieved May 3, 2026, from https://4ort.xyz/entity/tolvaptan
MLA “tolvaptan.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/tolvaptan.
BibTeX @misc{4ortxyz_tolvaptan_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{tolvaptan}}, year = {2026}, url = {https://4ort.xyz/entity/tolvaptan}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): tolvaptan — https://4ort.xyz/entity/tolvaptan (retrieved 2026-05-03)

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