Thyroid hormone receptor interactor 12

mammalian protein found in Homo sapiens
Protein protein Q21133854
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Thyroid hormone receptor interactor 12

Summary

Thyroid hormone receptor interactor 12 is a protein[1]. It is known by 11 alternative names across languages and contexts.[2]

Key Facts

  • Thyroid hormone receptor interactor 12's instance of is recorded as protein[3].
  • Thyroid hormone receptor interactor 12 is part of HECT, E3 ligase catalytic domain[4].
  • Thyroid hormone receptor interactor 12 is part of WWE domain superfamily[5].
  • Thyroid hormone receptor interactor 12 is part of Armadillo-like helical[6].
  • Thyroid hormone receptor interactor 12 is part of Armadillo-type fold[7].
  • Thyroid hormone receptor interactor 12 is part of HECT domain, protein family[8].
  • Thyroid hormone receptor interactor 12 is part of WWE domain, protein family[9].
  • Thyroid hormone receptor interactor 12 comprises WWE domain[10].
  • Thyroid hormone receptor interactor 12 comprises HECT domain[11].
  • Thyroid hormone receptor interactor 12's molecular function is recorded as thyroid hormone receptor binding[12].
  • Thyroid hormone receptor interactor 12's molecular function is recorded as protein binding[13].
  • Thyroid hormone receptor interactor 12's molecular function is recorded as ubiquitin-protein transferase activity[14].
  • Thyroid hormone receptor interactor 12's molecular function is recorded as transferase activity[15].
  • Thyroid hormone receptor interactor 12's molecular function is recorded as ubiquitin protein ligase activity[16].
  • Thyroid hormone receptor interactor 12's molecular function is recorded as ubiquitin-protein transferase activity[17].
  • Thyroid hormone receptor interactor 12's cell component is recorded as nucleus[18].
  • Thyroid hormone receptor interactor 12's cell component is recorded as nucleoplasm[19].
  • Thyroid hormone receptor interactor 12's cell component is recorded as cytosol[20].
  • Thyroid hormone receptor interactor 12's cell component is recorded as nuclear speck[21].
  • Thyroid hormone receptor interactor 12's cell component is recorded as cytoplasm[22].
  • Thyroid hormone receptor interactor 12's cell component is recorded as nucleus[23].
  • Thyroid hormone receptor interactor 12's cell component is recorded as nuclear speck[24].
  • Thyroid hormone receptor interactor 12's biological process is recorded as negative regulation of double-strand break repair[25].
  • Thyroid hormone receptor interactor 12's biological process is recorded as negative regulation of histone H2A K63-linked ubiquitination[26].
  • Thyroid hormone receptor interactor 12's biological process is recorded as DNA repair[27].

Why It Matters

Thyroid hormone receptor interactor 12 is known by 11 alternative names across languages and contexts.[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . The HECT domain of TRIP12 ubiquitinates substrates of the ubiquitin fusion degradation pathway. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Thyroid hormone receptor interactor 12. Retrieved May 3, 2026, from https://4ort.xyz/entity/thyroid-hormone-receptor-interactor-12
MLA “Thyroid hormone receptor interactor 12.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/thyroid-hormone-receptor-interactor-12.
BibTeX @misc{4ortxyz_thyroid-hormone-receptor-interactor-12_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Thyroid hormone receptor interactor 12}}, year = {2026}, url = {https://4ort.xyz/entity/thyroid-hormone-receptor-interactor-12}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Thyroid hormone receptor interactor 12 — https://4ort.xyz/entity/thyroid-hormone-receptor-interactor-12 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 8w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from
    Encoded by TRIP12
    Wikidata description mammalian protein found in Homo sapiens
    Molecular function thyroid hormone receptor binding, protein binding, ubiquitin-protein transferase activity +3
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.3.2.26, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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