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thymidine kinase 1

mammalian protein found in Homo sapiens
Protein protein Q21118621
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Summary

thymidine kinase 1 is a protein[1]. It is known by 6 alternative names across languages and contexts.[2]

Key Facts

  • Part of: thymidine kinase[3], P-loop containing nucleoside triphosphate hydrolase[4], Thymidine kinase, conserved site, protein family[5]
  • Has part(s): Thymidine kinase, conserved site[6]
  • Molecular function: transferase activity[7], nucleotide binding[8], nucleoside kinase activity[9], zinc ion binding[10], metal ion binding[11], kinase activity[12], protein binding[13], identical protein binding[14], ATP binding[15], thymidine kinase[16], thymidine kinase activity[17]
  • Cell component: cytoplasm[18], cytosol[19]
  • Biological process: DNA biosynthetic process[20], phosphorylation[21], pyrimidine nucleoside salvage[22], nucleobase-containing compound metabolic process[23], protein homotetramerization[24], deoxyribonucleoside monophosphate biosynthetic process[25], DNA metabolic process[26], nucleotide biosynthetic process[27], thymidine metabolic process[28]
  • Encoded by: TK1[29]
  • Found in taxon: Homo sapiens[30]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . Structure of a type II thymidine kinase with bound dTTP. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . A proteome-scale map of the human interactome network. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . A directed protein interaction network for investigating intracellular signal transduction. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Human cytosolic thymidine kinase. Purification and physical characterization of the enzyme from HeLa cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . Human cytosolic thymidine kinase. Purification and physical characterization of the enzyme from HeLa cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Human cytosolic thymidine kinase. Purification and physical characterization of the enzyme from HeLa cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . UniProt. Retrieved . wikidata.org.
  28. [30] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). thymidine kinase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/thymidine-kinase-1-q21118621
MLA “thymidine kinase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/thymidine-kinase-1-q21118621.
BibTeX @misc{4ortxyz_thymidine-kinase-1-q21118621_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{thymidine kinase 1}}, year = {2026}, url = {https://4ort.xyz/entity/thymidine-kinase-1-q21118621}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → TK1
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → transferase activity, nucleotide binding, nucleoside kinase activity +8
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.7.1.21, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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