thioredoxin reductase 1

mammalian protein found in Homo sapiens
Protein protein Q21106751
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Summary

thioredoxin reductase 1 is a protein[1]. It is known by 11 alternative names across languages and contexts.[2]

Key Facts

  • thioredoxin reductase 1's instance of is recorded as protein[3].
  • thioredoxin reductase 1 is part of Thioredoxin-like superfamily[4].
  • thioredoxin reductase 1 is part of FAD/NAD-linked reductase, dimerisation domain superfamily[5].
  • thioredoxin reductase 1 is part of Thioredoxin/glutathione reductase selenoprotein[6].
  • thioredoxin reductase 1 is part of FAD/NAD(P)-binding domain superfamily[7].
  • thioredoxin reductase 1 is part of FAD/NAD(P)-binding domain, protein family[8].
  • thioredoxin reductase 1 is part of Glutaredoxin family[9].
  • thioredoxin reductase 1 is part of Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, protein family[10].
  • thioredoxin reductase 1 is part of Pyridine nucleotide-disulphide oxidoreductase, class I, active site, protein family[11].
  • thioredoxin reductase 1 comprises Glutaredoxin domain[12].
  • thioredoxin reductase 1 comprises Pyridine nucleotide-disulphide oxidoreductase, class I, active site[13].
  • thioredoxin reductase 1 comprises FAD/NAD(P)-binding domain[14].
  • thioredoxin reductase 1 comprises Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain[15].
  • thioredoxin reductase 1's molecular function is recorded as protein-disulfide reductase activity[16].
  • thioredoxin reductase 1's molecular function is recorded as methylselenol reductase activity[17].
  • thioredoxin reductase 1's molecular function is recorded as flavin adenine dinucleotide binding[18].
  • thioredoxin reductase 1's molecular function is recorded as methylseleninic acid reductase activity[19].
  • thioredoxin reductase 1's molecular function is recorded as protein binding[20].
  • thioredoxin reductase 1's molecular function is recorded as electron transfer activity[21].
  • thioredoxin reductase 1's molecular function is recorded as oxidoreductase activity[22].
  • thioredoxin reductase 1's molecular function is recorded as oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor[23].
  • thioredoxin reductase 1's molecular function is recorded as thioredoxin-disulfide reductase activity[24].
  • thioredoxin reductase 1's molecular function is recorded as thioredoxin-disulfide reductase activity[25].
  • thioredoxin reductase 1's cell component is recorded as cytoplasm[26].
  • thioredoxin reductase 1's cell component is recorded as extracellular exosome[27].

Why It Matters

thioredoxin reductase 1 is known by 11 alternative names across languages and contexts.[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . UniProt. Retrieved . wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . Human thioredoxin reductase from HeLa cells: Selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . Human thioredoxin reductase from HeLa cells: Selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). thioredoxin reductase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/thioredoxin-reductase-1-q21106751
MLA “thioredoxin reductase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/thioredoxin-reductase-1-q21106751.
BibTeX @misc{4ortxyz_thioredoxin-reductase-1-q21106751_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{thioredoxin reductase 1}}, year = {2026}, url = {https://4ort.xyz/entity/thioredoxin-reductase-1-q21106751}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): thioredoxin reductase 1 — https://4ort.xyz/entity/thioredoxin-reductase-1-q21106751 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Found in taxon → Homo sapiens
    Mesh tree code → D08.811.682.667.750.500
    Wikidata description → mammalian protein found in Homo sapiens
    Pdb structure id → 2CFY, 2J3N, 2ZZ0 +4
    + 14 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 1.11.1.2, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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