Properties
Cites work
Apoptosis control by death and decoy receptors, Effects of angiogenesis inhibitors on multistage carcinogenesis in mice, Extension of life-span by introduction of telomerase into normal human cells, How tumors become angiogenic, Telomerase and the maintenance of chromosome ends, Telomere elongation in immortal human cells without detectable telomerase activity, src‐related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells, The IGF axis and programmed cell death, New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway, Changing views of the role of matrix metalloproteinases in metastasis, The INK4a/ARF tumor suppressor: one gene—two products—two pathways, The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene, A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis, At the crossroads of inflammation and tumorigenesis, Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization, Matrix metalloproteinases and the development of cancer, Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis, Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1, erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells, Mechanisms and consequences of activation of protein kinase B/Akt, The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product, A Matter of Life and Cell Death, The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin., Integrin signaling, Mitochondria and apoptosis, Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse, Creation of human tumour cells with defined genetic elements, Telomerase activity is sufficient to allow transformed cells to escape from crisis, Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis, p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest, p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective, A proinflammatory cytokine inhibits p53 tumor suppressor activity, Requirement for the CD95 Receptor-Ligand Pathway in c-Myc-Induced Apoptosis, Oncoprotein networks, Genetic manipulation of vascular adhesion molecules in mice, Programmed cell death by default in embryonic cells, fibroblasts, and cancer cells, Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation, Cell adhesion molecules of the immunoglobulin supergene family and their role in malignant transformation and progression to metastatic disease, v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation, The neural cell adhesion molecule NCAM in multiple myeloma, Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics, Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo, Lessons from hereditary colorectal cancer, ONCOGENESIS: Landscaping the Cancer Terrain, Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes, Genetic instabilities in human cancers, p53, the cellular gatekeeper for growth and division, ECM signalling: orchestrating cell behaviour and misbehaviour., Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability, The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis, Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18), Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant, TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights, The clonal evolution of tumor cell populations, Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells, Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer, Oncogenes as inducers of tumor angiogenesis, How many mutations are required for tumorigenesis? Implications from human cancer data, Ras - a versatile cellular switch, Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a, A survey of telomerase activity in human cancer, Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas, Tumorigenic conversion of immortal human keratinocytes through stromal cell activation, Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene, The war on cancer, Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention, Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2., p53-dependent apoptosis suppresses tumor growth and progression in vivo, Caspases: Enemies Within, Integrins and cancer, Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells, Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span, VEGFs, receptors and angiogenesis, Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity, The retinoblastoma protein and cell cycle control, ECM and Cell Surface Proteolysis: Regulating Cellular Ecology, The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases, Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts, Cell death: the significance of apoptosis, Growth factor receptor tyrosine kinases, Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening, Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma, Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
Issue
1
Page(s)
57–70
Publication date
January 1, 2000
Title
The Hallmarks of Cancer
Volume
100
