TERF2 interacting protein

mammalian protein found in Homo sapiens

Protein protein Q21136120

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TERF2 interacting protein

Summary

TERF2 interacting protein is a protein^[1].

Key Facts

TERF2 interacting protein's instance of is recorded as protein^[2].
TERF2 interacting protein's subclass of is recorded as protein^[3].
TERF2 interacting protein's UniProt protein ID is recorded as Q9NYB0^[4].
TERF2 interacting protein's RefSeq protein ID is recorded as NP_061848^[5].
TERF2 interacting protein's PDB structure ID is recorded as 1FEX^[6].
TERF2 interacting protein's PDB structure ID is recorded as 3K6G^[7].
TERF2 interacting protein's PDB structure ID is recorded as 4RQI^[8].
TERF2 interacting protein's molecular function is recorded as DNA binding^[9].
TERF2 interacting protein's molecular function is recorded as telomeric DNA binding^[10].
TERF2 interacting protein's molecular function is recorded as protein binding^[11].
TERF2 interacting protein's molecular function is recorded as G-rich strand telomeric DNA binding^[12].
TERF2 interacting protein's molecular function is recorded as phosphatase binding^[13].
TERF2 interacting protein's molecular function is recorded as protein binding^[14].
TERF2 interacting protein's molecular function is recorded as DNA binding^[15].
TERF2 interacting protein's molecular function is recorded as telomeric DNA binding^[16].
TERF2 interacting protein's cell component is recorded as nuclear telomere cap complex^[17].
TERF2 interacting protein's cell component is recorded as nuclear envelope^[18].
TERF2 interacting protein's cell component is recorded as chromosome^[19].
TERF2 interacting protein's cell component is recorded as shelterin complex^[20].
TERF2 interacting protein's cell component is recorded as telomere^[21].
TERF2 interacting protein's cell component is recorded as nuclear chromosome^[22].
TERF2 interacting protein's cell component is recorded as Mre11 complex^[23].
TERF2 interacting protein's cell component is recorded as nucleus^[24].
TERF2 interacting protein's cell component is recorded as nucleoplasm^[25].
TERF2 interacting protein's cell component is recorded as cytosol^[26].

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Quick Facts

Instance of protein

Subclass of protein

Properties

Biological process negative regulation of DNA recombination at telomere, telomere maintenance via telomerase, protection from non-homologous end joining at telomere, regulation of double-strand break repair via homologous recombination, transcription, DNA-templated, positive regulation of peptidyl-serine phosphorylation, protein localization to chromosome, telomeric region, positive regulation of protein acetylation, telomere maintenance via telomere lengthening, positive regulation of NF-kappaB transcription factor activity, positive regulation of I-kappaB kinase/NF-kappaB signaling, telomere maintenance, telomere capping, negative regulation of protein phosphorylation, regulation of transcription, DNA-templated, regulation of telomere maintenance, negative regulation of telomere maintenance, positive regulation of NIK/NF-kappaB signaling, telomere maintenance, regulation of transcription, DNA-templated, telomere maintenance via telomere lengthening

Cell component nuclear telomere cap complex, nuclear envelope, chromosome, shelterin complex, telomere, nuclear chromosome, Mre11 complex, nucleus, nucleoplasm, cytosol, nuclear body, cytoplasm, cytosol, shelterin complex

Encoded by TERF2IP

Found in taxon Homo sapiens

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, telomeric DNA binding, protein binding, G-rich strand telomeric DNA binding, phosphatase binding, protein binding, DNA binding, telomeric DNA binding

External References (4)

Ensembl protein id ENSP00000300086, ENSP00000454399, ENSP00000456092, ENSP00000499565

Pdb structure id 1FEX, 3K6G, 4RQI

Refseq protein id NP_061848

Uniprot protein id Q9NYB0

🏷️ Also known as

en dopamine receptor-interacting protein 5 en hRap1 en RAP1 homolog en repressor/activator protein 1 homolog en telomeric repeat-binding factor 2-interacting protein 1 en TERF2 interacting protein en TERF2-interacting telomeric protein 1 en TERF2IP en TRF2-interacting telomeric RAP1 protein

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ TERF2 interacting protein — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ TERF2 interacting protein — subclass of (P279): protein. Q905695. Retrieved 2016-12-01. wikidata.org.
[4] ↑ TERF2 interacting protein — UniProt protein ID (P352): Q9NYB0. Q905695. Retrieved 2019-11-13. wikidata.org.
[5] ↑ TERF2 interacting protein — RefSeq protein ID (P637): NP_061848. Q20641742. Retrieved 2020-05-30. wikidata.org.
[6] ↑ TERF2 interacting protein — PDB structure ID (P638): 1FEX. Q905695. Retrieved 2016-08-09. wikidata.org.
[7] ↑ TERF2 interacting protein — PDB structure ID (P638): 3K6G. Q905695. Retrieved 2016-08-09. wikidata.org.
[8] ↑ TERF2 interacting protein — PDB structure ID (P638): 4RQI. Q905695. Retrieved 2016-08-09. wikidata.org.
[9] ↑ TERF2 interacting protein — molecular function (P680): DNA binding. GOA. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ TERF2 interacting protein — molecular function (P680): telomeric DNA binding. Identification of human Rap1: implications for telomere evolution. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ TERF2 interacting protein — molecular function (P680): protein binding. Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ TERF2 interacting protein — molecular function (P680): G-rich strand telomeric DNA binding. MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ TERF2 interacting protein — molecular function (P680): phosphatase binding. PRL-3 activates NF-κB signaling pathway by interacting with RAP1. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ TERF2 interacting protein — molecular function (P680): protein binding. ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ TERF2 interacting protein — molecular function (P680): DNA binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ TERF2 interacting protein — molecular function (P680): telomeric DNA binding. Identification of human Rap1: implications for telomere evolution. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ TERF2 interacting protein — cell component (P681): nuclear telomere cap complex. PTOP interacts with POT1 and regulates its localization to telomeres. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ TERF2 interacting protein — cell component (P681): nuclear envelope. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ TERF2 interacting protein — cell component (P681): chromosome. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ TERF2 interacting protein — cell component (P681): shelterin complex. Characterization of the DNA binding specificity of Shelterin complexes. Retrieved 2017-10-24. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ TERF2 interacting protein — cell component (P681): telomere. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ TERF2 interacting protein — cell component (P681): nuclear chromosome. Identification of human Rap1: implications for telomere evolution. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ TERF2 interacting protein — cell component (P681): Mre11 complex. The human Rap1 protein complex and modulation of telomere length. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ TERF2 interacting protein — cell component (P681): nucleus. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ TERF2 interacting protein — cell component (P681): nucleoplasm. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ TERF2 interacting protein — cell component (P681): cytosol. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ TERF2 interacting protein is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). TERF2 interacting protein. Retrieved May 3, 2026, from https://4ort.xyz/entity/terf2-interacting-protein

MLA

“TERF2 interacting protein.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/terf2-interacting-protein.

BibTeX

@misc{4ortxyz_terf2-interacting-protein_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{TERF2 interacting protein}}, year = {2026}, url = {https://4ort.xyz/entity/terf2-interacting-protein}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): TERF2 interacting protein — https://4ort.xyz/entity/terf2-interacting-protein (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/terf2-interacting-protein · Last refreshed: May 3, 2026