Telomerase reverse transcriptase

mammalian protein found in Homo sapiens
Protein protein Q7697809
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Telomerase reverse transcriptase

Summary

Telomerase reverse transcriptase is a protein[1].

Key Facts

  • Telomerase reverse transcriptase's instance of is recorded as protein[2].
  • Telomerase reverse transcriptase is part of telomerase[3].
  • Telomerase reverse transcriptase is part of Telomerase reverse transcriptase[4].
  • Telomerase reverse transcriptase is part of Telomerase ribonucleoprotein complex - RNA-binding domain, protein family[5].
  • Telomerase reverse transcriptase is part of Reverse transcriptase domain, protein family[6].
  • Telomerase reverse transcriptase comprises Telomerase ribonucleoprotein complex - RNA-binding domain[7].
  • Telomerase reverse transcriptase comprises Reverse transcriptase domain[8].
  • Telomerase reverse transcriptase's molecular function is recorded as transferase activity[9].
  • Telomerase reverse transcriptase's molecular function is recorded as DNA binding[10].
  • Telomerase reverse transcriptase's molecular function is recorded as nucleotidyltransferase activity[11].
  • Telomerase reverse transcriptase's molecular function is recorded as telomeric DNA binding[12].
  • Telomerase reverse transcriptase's molecular function is recorded as tRNA binding[13].
  • Telomerase reverse transcriptase's molecular function is recorded as metal ion binding[14].
  • Telomerase reverse transcriptase's molecular function is recorded as RNA-directed 5'-3' RNA polymerase activity[15].
  • Telomerase reverse transcriptase's molecular function is recorded as telomerase RNA reverse transcriptase activity[16].
  • Telomerase reverse transcriptase's molecular function is recorded as protein binding[17].
  • Telomerase reverse transcriptase's molecular function is recorded as transcription coactivator binding[18].
  • Telomerase reverse transcriptase's molecular function is recorded as telomerase RNA binding[19].
  • Telomerase reverse transcriptase's molecular function is recorded as telomerase activity[20].
  • Telomerase reverse transcriptase's molecular function is recorded as protein homodimerization activity[21].
  • Telomerase reverse transcriptase's molecular function is recorded as chaperone binding[22].
  • Telomerase reverse transcriptase's molecular function is recorded as template-free RNA nucleotidyltransferase[23].
  • Telomerase reverse transcriptase's molecular function is recorded as RNA binding[24].
  • Telomerase reverse transcriptase's molecular function is recorded as protein C-terminus binding[25].
  • Telomerase reverse transcriptase's molecular function is recorded as protein N-terminus binding[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Modulation of human telomerase reverse transcriptase in hepatocellular carcinoma. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . The AAA-ATPase NVL2 is a telomerase component essential for holoenzyme assembly. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Telomerase modulates Wnt signalling by association with target gene chromatin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Specificity and Stoichiometry of Subunit Interactions in the Human Telomerase Holoenzyme Assembled In Vivo. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Structure of active dimeric human telomerase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . Functional requirement of p23 and Hsp90 in telomerase complexes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Protein RNA and protein protein interactions mediate association of human EST1A/SMG6 with telomerase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . The Pin2/TRF1-Interacting Protein PinX1 Is a Potent Telomerase Inhibitor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . The Pin2/TRF1-Interacting Protein PinX1 Is a Potent Telomerase Inhibitor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Telomerase reverse transcriptase. Retrieved May 3, 2026, from https://4ort.xyz/entity/telomerase-reverse-transcriptase-q7697809
MLA “Telomerase reverse transcriptase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/telomerase-reverse-transcriptase-q7697809.
BibTeX @misc{4ortxyz_telomerase-reverse-transcriptase-q7697809_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Telomerase reverse transcriptase}}, year = {2026}, url = {https://4ort.xyz/entity/telomerase-reverse-transcriptase-q7697809}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Telomerase reverse transcriptase — https://4ort.xyz/entity/telomerase-reverse-transcriptase-q7697809 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 28d ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Uniprot protein id O14746
    Ec enzyme number 2.7.7.49
    Umls cui C0754515
    Refseq protein id NP_001180305, NP_937983
    + 13 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.7.7.49, [[:toollabs:quickstatements/#/batch/261457|batch #261457]]"
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