TBX3

protein-coding gene in the species Homo sapiens
Gene gene Q18031866
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TBX3

Summary

TBX3 is a gene[1]. TBX3 ranks in the top 2% of gene entities by monthly Wikipedia readership (16 views/month).[2]

Key Facts

  • TBX3's instance of is recorded as gene[3].
  • TBX3 is a type of protein-coding gene[4].
  • TBX3's Commons category is recorded as T-box protein 3, tbx3[5].
  • TBX3's HomoloGene ID is recorded as 4371[6].
  • TBX3's genomic start is recorded as 115108059[7].
  • TBX3's genomic start is recorded as 114670255[8].
  • TBX3's genomic end is recorded as 115121969[9].
  • TBX3's genomic end is recorded as 114684175[10].
  • TBX3's ortholog is recorded as Tbx3[11].
  • TBX3's ortholog is recorded as Tbx3[12].
  • TBX3's ortholog is recorded as tbx3a[13].
  • TBX3's encodes is recorded as T-box transcription factor 3[14].
  • TBX3's found in taxon is recorded as Homo sapiens[15].
  • TBX3's chromosome is recorded as human chromosome 12[16].
  • TBX3's decreased expression in is recorded as obesity[17].
  • TBX3's increased expression in is recorded as fibrosarcoma[18].
  • TBX3's increased expression in is recorded as breast cancer[19].
  • TBX3's increased expression in is recorded as chondrosarcoma[20].
  • TBX3's increased expression in is recorded as stomach carcinoma[21].
  • TBX3's increased expression in is recorded as head and neck cancer[22].
  • TBX3's increased expression in is recorded as liposarcoma[23].
  • TBX3's increased expression in is recorded as liver cancer[24].
  • TBX3's increased expression in is recorded as non-small-cell lung carcinoma[25].
  • TBX3's increased expression in is recorded as melanoma[26].
  • TBX3's increased expression in is recorded as ovarian cancer[27].

Why It Matters

TBX3 ranks in the top 2% of gene entities by monthly Wikipedia readership (16 views/month).[2] TBX3 is known by 6 alternative names across languages and contexts.[28]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . ensembl Release 106. wikidata.org.
  2. [4] . Ensembl Release 87. wikidata.org.
  3. [5] . wikidata.org.
  4. [6] . Q20641742. Retrieved . wikidata.org.
  5. [7] . ensembl Release 106. wikidata.org.
  6. [8] . ensembl Release 106. wikidata.org.
  7. [9] . ensembl Release 106. wikidata.org.
  8. [10] . ensembl Release 106. wikidata.org.
  9. [11] . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  10. [12] . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  11. [13] . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  12. [14] . Q905695. Retrieved . wikidata.org.
  13. [15] . ensembl Release 106. wikidata.org.
  14. [16] . ensembl Release 106. wikidata.org.
  15. [17] . Functional identity of hypothalamic melanocortin neurons depends on Tbx3. wikidata.org.
  16. [18] . The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes. wikidata.org.
  17. [19] . TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases. wikidata.org.
  18. [20] . The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes. wikidata.org.
  19. [21] . Tbx3 overexpression in human gastric cancer is correlated with advanced tumor stage and nodal status and promotes cancer cell growth and invasion. wikidata.org.
  20. [22] . Tbx3 represses PTEN and is over-expressed in head and neck squamous cell carcinoma. wikidata.org.
  21. [23] . The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes. wikidata.org.
  22. [24] . Expression of TBX3 in Hepatocellular Carcinoma and Its Clinical Implication. wikidata.org.
  23. [25] . T-box 3 overexpression is associated with poor prognosis of non-small cell lung cancer. wikidata.org.
  24. [26] . The T-box transcription factor, TBX3, is sufficient to promote melanoma formation and invasion. wikidata.org.
  25. [27] . Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients. wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). TBX3. Retrieved May 3, 2026, from https://4ort.xyz/entity/tbx3
MLA “TBX3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/tbx3.
BibTeX @misc{4ortxyz_tbx3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{TBX3}}, year = {2026}, url = {https://4ort.xyz/entity/tbx3}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): TBX3 — https://4ort.xyz/entity/tbx3 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 23h ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    Genetic association colorectal cancer, ulnar-mammary syndrome
    Altered regulation leads to bladder cancer
    Decreased expression in obesity
    Subclass of
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||gsw */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/32527|batch #32527]]: human gene name and description in Alemannic"
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