TATA-box binding protein associated factor 1

mammalian protein found in Homo sapiens
Protein protein Q21170876
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Summary

TATA-box binding protein associated factor 1 is a protein[1]. It is known by 14 alternative names across languages and contexts.[2]

Key Facts

  • Subclass of: protein[3]
  • Part of: Transcription initiation factor TFIID subunit 1, animal[4], Bromodomain-like superfamily[5], TAFII-230 TBP-binding domain superfamily[6], Transcription initiation factor TFIID subunit 1, domain of unknown function, protein family[7], TAFII-230 TBP-binding domain, protein family[8], bromodomain protein family[9], Bromodomain, conserved site, protein family[10]
  • Has part(s): Bromodomain, conserved site[11], Transcription initiation factor TFIID subunit 1, domain of unknown function[12], bromodomain[13], TAFII-230 TBP-binding[14]
  • Molecular function: transferase activity[15], nucleotide binding[16], DNA binding[17], transcription coactivator activity[18], p53 binding[19], transcription factor binding[20], protein binding[21], lysine-acetylated histone binding[22], TBP-class protein binding[23], acyltransferase activity[24], ATP binding[25], protein serine/threonine kinase activity[26], histone acetyltransferase activity[27], kinase activity[28]
  • Cell component: nucleoplasm[29], MLL1 complex[30], nucleus[31], nucleolus[32], transcription regulator complex[33], transcription factor TFIID complex[34]
  • Biological process: phosphorylation[35], RNA polymerase II preinitiation complex assembly[36], transcription by RNA polymerase II[37], positive regulation of transcription initiation from RNA polymerase II promoter[38], transcription, DNA-templated[39], peptidyl-serine phosphorylation[40], DNA-templated transcription, initiation[41], protein autophosphorylation[42], cell cycle[43], transcription initiation from RNA polymerase II promoter[44], peptidyl-threonine phosphorylation[45], positive regulation of proteasomal ubiquitin-dependent protein catabolic process[46], positive regulation of transcription by RNA polymerase II[47]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . UniProt. Retrieved . wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . An acetylation switch in p53 mediates holo-TFIID recruitment. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . An acetylation switch in p53 mediates holo-TFIID recruitment. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Functional Analysis of the Human TAFII250 N-Terminal Kinase Domain. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . Structural and functional insight into TAF1–TAF7, a subcomplex of transcription factor II D. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . The cell cycle regulatory factor TAF1 stimulates ribosomal DNA transcription by binding to the activator UBF. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  37. [39] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  38. [40] ↑ . TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  39. [41] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  40. [42] ↑ . Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  41. [43] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  42. [44] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  43. [45] ↑ . Phosphorylation of p53 by TAF1 Inactivates p53-Dependent Transcription in the DNA Damage Response. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  44. [46] ↑ . Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  45. [47] ↑ . Functional Analysis of the Human TAFII250 N-Terminal Kinase Domain. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

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APA 4ort.xyz Knowledge Graph. (2026). TATA-box binding protein associated factor 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/tata-box-binding-protein-associated-factor-1-q21170876
MLA “TATA-box binding protein associated factor 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/tata-box-binding-protein-associated-factor-1-q21170876.
BibTeX @misc{4ortxyz_tata-box-binding-protein-associated-factor-1-q21170876_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{TATA-box binding protein associated factor 1}}, year = {2026}, url = {https://4ort.xyz/entity/tata-box-binding-protein-associated-factor-1-q21170876}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Subclass of → protein
    Wikidata description → mammalian protein found in Homo sapiens
    Encoded by → TAF1
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.3.1.48, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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