TANK binding kinase 1

mammalian protein found in Homo sapiens

Protein protein Q21111280

Press Enter · cited answer in seconds

Summary

TANK binding kinase 1 is a protein^[1]. It is known by 7 alternative names across languages and contexts.^[2]

Key Facts

TANK binding kinase 1's instance of is recorded as protein^[3].
TANK binding kinase 1's physically interacts with is recorded as Viroporin 3a^[4].
TANK binding kinase 1 is part of Protein kinase-like domain superfamily^[5].
TANK binding kinase 1 is part of Protein kinase domain, protein family^[6].
TANK binding kinase 1 is part of Protein kinase, ATP binding site, protein family^[7].
TANK binding kinase 1 comprises protein kinase domain^[8].
TANK binding kinase 1 comprises protein kinase, ATP binding site^[9].
TANK binding kinase 1's molecular function is recorded as transferase activity^[10].
TANK binding kinase 1's molecular function is recorded as nucleotide binding^[11].
TANK binding kinase 1's molecular function is recorded as kinase activity^[12].
TANK binding kinase 1's molecular function is recorded as protein serine/threonine kinase activity^[13].
TANK binding kinase 1's molecular function is recorded as phosphoprotein binding^[14].
TANK binding kinase 1's molecular function is recorded as protein binding^[15].
TANK binding kinase 1's molecular function is recorded as nucleic acid binding^[16].
TANK binding kinase 1's molecular function is recorded as ATP binding^[17].
TANK binding kinase 1's molecular function is recorded as protein kinase activity^[18].
TANK binding kinase 1's molecular function is recorded as identical protein binding^[19].
TANK binding kinase 1's molecular function is recorded as protein serine/threonine kinase activity^[20].
TANK binding kinase 1's molecular function is recorded as protein phosphatase binding^[21].
TANK binding kinase 1's molecular function is recorded as identical protein binding^[22].
TANK binding kinase 1's cell component is recorded as cytoplasm^[23].
TANK binding kinase 1's cell component is recorded as cytosol^[24].
TANK binding kinase 1's cell component is recorded as endosome membrane^[25].
TANK binding kinase 1's cell component is recorded as nucleoplasm^[26].
TANK binding kinase 1's cell component is recorded as aggresome^[27].

Why It Matters

TANK binding kinase 1 is known by 7 alternative names across languages and contexts.^[2]

⭐ Popularity Graph

0/100 long tail

Quick Facts

Instance of protein

Part of Protein kinase-like domain superfamily, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family

Properties

Biological process phosphorylation, positive regulation of interferon-alpha production, immune system process, response to virus, positive regulation of xenophagy, negative regulation of gene expression, positive regulation of peptidyl-serine phosphorylation, TRIF-dependent toll-like receptor signaling pathway, type I interferon production, defense response to virus, peptidyl-serine phosphorylation, regulation of neuron death, activation of innate immune response, positive regulation of I-kappaB kinase/NF-kappaB signaling, negative regulation of type I interferon production, innate immune response, viral process, inflammatory response, I-kappaB kinase/NF-kappaB signaling, positive regulation of type I interferon production, positive regulation of transcription by RNA polymerase II, dendritic cell proliferation, defense response to Gram-positive bacterium, positive regulation of interferon-beta production, regulation of type I interferon production, positive regulation of macroautophagy, peptidyl-threonine phosphorylation, protein phosphorylation, cellular response to cytokine stimulus, regulation of gene expression, peptidyl-serine phosphorylation, regulation of cellular metabolic process, positive regulation of type I interferon-mediated signaling pathway, regulation of type I interferon production, innate immune response

Cell component cytoplasm, cytosol, endosome membrane, nucleoplasm, aggresome

Ec enzyme number 2.7.11.1

Encoded by TBK1

Found in taxon Homo sapiens

Has part(s) protein kinase domain, protein kinase, ATP binding site

Molecular function transferase activity, nucleotide binding, kinase activity, protein serine/threonine kinase activity, phosphoprotein binding, protein binding, nucleic acid binding, ATP binding, protein kinase activity, identical protein binding, protein serine/threonine kinase activity, protein phosphatase binding, identical protein binding

Physically interacts with Viroporin 3a

External References (4)

Ensembl protein id ENSP00000329967, ENSP00000444428, ENSP00000445628, ENSP00000445834

Pdb structure id 4EFO, 4EUT, 4EUU, 4IM0, 4IM2, 4IM3, 4IW0, 4IWO, 4IWP, 4IWQ

Refseq protein id NP_037386, XP_005268866, XP_005268867

Uniprot protein id Q9UHD2

🏷️ Also known as

en NF-kappa-B-activating kinase en NF-kB-activating kinase en serine/threonine-protein kinase TBK1 en T2K en TANK binding kinase 1 en TANK-binding kinase 1 en TBK1

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). TANK binding kinase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/tank-binding-kinase-1-q21111280

MLA

“TANK binding kinase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/tank-binding-kinase-1-q21111280.

BibTeX

@misc{4ortxyz_tank-binding-kinase-1-q21111280_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{TANK binding kinase 1}}, year = {2026}, url = {https://4ort.xyz/entity/tank-binding-kinase-1-q21111280}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): TANK binding kinase 1 — https://4ort.xyz/entity/tank-binding-kinase-1-q21111280 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/tank-binding-kinase-1-q21111280 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

11w ago · Boghog · 2026-07-24 view diff on Wikidata ↗

Imported from → —

Encoded by → TBK1

Wikidata description → mammalian protein found in Homo sapiens

Molecular function → transferase activity, nucleotide binding, kinase activity +10

+ 12 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ Ec enzyme number: 2.7.11.1, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"

Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.