tacrolimus

Immunosuppressive Rx drug
ChemicalSubstance type_of_chemical_entity Q411648
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tacrolimus

Summary

tacrolimus is a type of chemical entity[1]. tacrolimus ranks in the top 2% of type_of_chemical_entity entities by monthly Wikipedia readership (1,948 views/month).[2]

Key Facts

  • tacrolimus's instance of is recorded as type of chemical entity[3].
  • tacrolimus's physically interacts with is recorded as FKBP prolyl isomerase 1A[4].
  • tacrolimus's manufacturer is recorded as Pfizer[5].
  • tacrolimus's canonical SMILES is recorded as CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC[6].
  • tacrolimus's chemical formula is recorded as C₄₄H₆₉NO₁₂[7].
  • tacrolimus is a type of alkaloid[8].
  • tacrolimus is a type of macrolides[9].
  • tacrolimus is part of FK506 binding[10].
  • tacrolimus is used for medication[11].
  • tacrolimus is used for chemical probe[12].
  • tacrolimus's Commons category is recorded as Tacrolimus[13].
  • tacrolimus's route of administration is recorded as oral administration[14].
  • tacrolimus's route of administration is recorded as intravenous infusion and defusionههبهلخل[15].
  • tacrolimus's molecular function is recorded as FK506 binding[16].
  • tacrolimus's found in taxon is recorded as Streptomyces hygroscopicus[17].
  • tacrolimus's found in taxon is recorded as Streptomyces tacrolimicus[18].
  • tacrolimus's found in taxon is recorded as Streptomyces clavuligerus[19].
  • tacrolimus's found in taxon is recorded as Penicillium[20].
  • tacrolimus's significant drug interaction is recorded as valganciclovir[21].
  • tacrolimus's significant drug interaction is recorded as ganciclovir[22].
  • tacrolimus's significant drug interaction is recorded as cyclosporine[23].
  • tacrolimus's significant drug interaction is recorded as nabumetone[24].
  • tacrolimus's significant drug interaction is recorded as naproxen[25].
  • tacrolimus's significant drug interaction is recorded as celecoxib[26].
  • tacrolimus's significant drug interaction is recorded as Diclofenac[27].

Why It Matters

tacrolimus ranks in the top 2% of type_of_chemical_entity entities by monthly Wikipedia readership (1,948 views/month).[2] tacrolimus has Wikipedia articles in 22 language editions, a strong signal of global cultural recognition.[28] tacrolimus is known by 17 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . wikidata.org.
  2. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [5] . pfizer.com. pfizer.com. Provenance: wikidata.org.
  4. [6] . PubChem. Retrieved . wikidata.org.
  5. [7] . PubChem. Retrieved . wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . Gene Ontology release 2019-11-16. wikidata.org.
  9. [11] . wikidata.org.
  10. [12] . chemicalprobes.org. chemicalprobes.org. Provenance: wikidata.org.
  11. [13] . wikidata.org.
  12. [14] . wikidata.org.
  13. [15] . wikidata.org.
  14. [16] . wikidata.org.
  15. [17] . Enhancement of ascomycin production via a combination of atmospheric and room temperature plasma mutagenesis in Streptomyces hygroscopicus and medium optimization. wikidata.org.
  16. [18] . Characterisation of a γ-butyrolactone receptor of Streptomyces tacrolimicus: effect on sporulation and tacrolimus biosynthesis. wikidata.org.
  17. [19] . Liquid chromatography-mass spectrometry characterization of FK506 biosynthetic intermediates in Streptomyces clavuligerus KCTC 10561BP.. wikidata.org.
  18. [20] . Amino Acid Conjugated Anthraquinones from the Marine-Derived Fungus Penicillium sp. SCSIO sof101.. wikidata.org.
  19. [21] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  20. [22] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  21. [23] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  22. [24] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  23. [25] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  24. [26] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  25. [27] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). tacrolimus. Retrieved May 3, 2026, from https://4ort.xyz/entity/tacrolimus
MLA “tacrolimus.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/tacrolimus.
BibTeX @misc{4ortxyz_tacrolimus_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{tacrolimus}}, year = {2026}, url = {https://4ort.xyz/entity/tacrolimus}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): tacrolimus — https://4ort.xyz/entity/tacrolimus (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/tacrolimus · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 1d ago · Twofivesixbot bot · 2026-05-19 view diff on Wikidata ↗
    Found in taxon Streptomyces hygroscopicus, Streptomyces tacrolimicus, Streptomyces clavuligerus +1
    Medical condition treated atopic dermatitis, graft-versus-host disease, lupus nephritis +10
    Manufacturer Pfizer
    Physically interacts with FKBP prolyl isomerase 1A
    + 18 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|7 */ [[Property:P2347]]: 23272, mv to monolingual text names on YSO statements"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.