T-box 21

mammalian protein found in Mus musculus
Protein protein Q21495410
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T-box 21

Summary

T-box 21 is a protein[1].

Key Facts

  • T-box 21's instance of is recorded as protein[2].
  • T-box 21's subclass of is recorded as protein[3].
  • T-box 21's UniProt protein ID is recorded as Q9JKD8[4].
  • T-box 21's part of is recorded as p53-like transcription factor, DNA-binding[5].
  • T-box 21's part of is recorded as Transcription factor, T-box[6].
  • T-box 21's part of is recorded as T-box superfamily[7].
  • T-box 21's part of is recorded as Transcription factor, T-box, conserved site, protein family[8].
  • T-box 21's has part is recorded as Transcription factor, T-box, conserved site[9].
  • T-box 21's RefSeq protein ID is recorded as NP_062380[10].
  • T-box 21's molecular function is recorded as DNA-binding transcription factor activity[11].
  • T-box 21's molecular function is recorded as protein binding[12].
  • T-box 21's molecular function is recorded as sequence-specific DNA binding[13].
  • T-box 21's molecular function is recorded as DNA binding[14].
  • T-box 21's cell component is recorded as soma[15].
  • T-box 21's cell component is recorded as nucleus[16].
  • T-box 21's biological process is recorded as cellular response to organic substance[17].
  • T-box 21's biological process is recorded as positive regulation of isotype switching to IgG isotypes[18].
  • T-box 21's biological process is recorded as response to virus[19].
  • T-box 21's biological process is recorded as T cell differentiation[20].
  • T-box 21's biological process is recorded as regulation of transcription, DNA-templated[21].
  • T-box 21's biological process is recorded as lymphocyte migration[22].
  • T-box 21's biological process is recorded as transcription, DNA-templated[23].
  • T-box 21's biological process is recorded as regulation of immune response[24].
  • T-box 21's biological process is recorded as negative regulation of transcription by RNA polymerase II[25].
  • T-box 21's biological process is recorded as negative regulation of interleukin-2 production[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . wikidata.org.
  8. [9] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . Q20641742. Retrieved . wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . Lysine 313 of T-box is crucial for modulation of protein stability, DNA binding, and threonine phosphorylation of T-bet. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Arx homeobox gene is essential for development of mouse olfactory system. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . T-bet regulates T-independent IgG2a class switching. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . T-bet regulates T-independent IgG2a class switching. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Lysine 313 of T-box is crucial for modulation of protein stability, DNA binding, and threonine phosphorylation of T-bet. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). T-box 21. Retrieved May 3, 2026, from https://4ort.xyz/entity/t-box-21
MLA “T-box 21.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/t-box-21.
BibTeX @misc{4ortxyz_t-box-21_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{T-box 21}}, year = {2026}, url = {https://4ort.xyz/entity/t-box-21}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): T-box 21 — https://4ort.xyz/entity/t-box-21 (retrieved 2026-05-03)

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