Synoviolin 1

mammalian protein found in Homo sapiens
Protein protein Q7395294
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Synoviolin 1

Summary

Synoviolin 1 is a protein[1]. It is known by 8 alternative names across languages and contexts.[2]

Key Facts

  • Synoviolin 1's instance of is recorded as protein[3].
  • Synoviolin 1 is part of E3 ubiquitin-protein ligase synoviolin/Hrd1[4].
  • Synoviolin 1 is part of Zinc finger, RING/FYVE/PHD-type[5].
  • Synoviolin 1 is part of Endoplasmic Reticular Retrotranslocon[6].
  • Synoviolin 1 is part of Zinc finger, RING-type, protein family[7].
  • Synoviolin 1 comprises Zinc finger, RING-type[8].
  • Synoviolin 1's EC enzyme number is recorded as 6.3.2.-[9].
  • Synoviolin 1's HomoloGene ID is recorded as 32700[10].
  • Synoviolin 1's molecular function is recorded as chaperone binding[11].
  • Synoviolin 1's molecular function is recorded as unfolded protein binding[12].
  • Synoviolin 1's molecular function is recorded as ATPase binding[13].
  • Synoviolin 1's molecular function is recorded as metal ion binding[14].
  • Synoviolin 1's molecular function is recorded as protein binding[15].
  • Synoviolin 1's molecular function is recorded as ubiquitin-specific protease binding[16].
  • Synoviolin 1's molecular function is recorded as ubiquitin protein ligase activity[17].
  • Synoviolin 1's molecular function is recorded as ubiquitin protein ligase activity[18].
  • Synoviolin 1's molecular function is recorded as transferase activity[19].
  • Synoviolin 1's molecular function is recorded as unfolded protein binding[20].
  • Synoviolin 1's molecular function is recorded as ubiquitin protein ligase activity[21].
  • Synoviolin 1's molecular function is recorded as ubiquitin-specific protease binding[22].
  • Synoviolin 1's cell component is recorded as integral component of membrane[23].
  • Synoviolin 1's cell component is recorded as endoplasmic reticulum membrane[24].
  • Synoviolin 1's cell component is recorded as nucleoplasm[25].
  • Synoviolin 1's cell component is recorded as smooth endoplasmic reticulum[26].
  • Synoviolin 1's cell component is recorded as integral component of endoplasmic reticulum membrane[27].

Why It Matters

Synoviolin 1 is known by 8 alternative names across languages and contexts.[2]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . wikidata.org.
  5. [7] . wikidata.org.
  6. [8] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . wikidata.org.
  9. [11] . A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . Ubiquitin-specific protease 25 functions in Endoplasmic Reticulum-associated degradation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . A deubiquitinase negatively regulates retro-translocation of nonubiquitinated substrates. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . Endoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative disease. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . Ubiquitin-specific protease 25 functions in Endoplasmic Reticulum-associated degradation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Synoviolin 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/synoviolin-1
MLA “Synoviolin 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/synoviolin-1.
BibTeX @misc{4ortxyz_synoviolin-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Synoviolin 1}}, year = {2026}, url = {https://4ort.xyz/entity/synoviolin-1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Synoviolin 1 — https://4ort.xyz/entity/synoviolin-1 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 7w ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Uniprot protein id Q86TM6
    Ec enzyme number 6.3.2.-
    Transporter classification database id 3.A.16.1.4
    Refseq protein id NP_115807, NP_757385, XP_011543605
    + 13 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.3.2.27, [[:toollabs:quickstatements/#/batch/261457|batch #261457]]"
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