Surfactant protein A1

mammalian protein found in Homo sapiens

Protein protein Q7259541

Press Enter · cited answer in seconds

Summary

Surfactant protein A1 is a protein^[1].

Key Facts

Part of: C-type lectin-like/link domain superfamily^[2], C-type lectin fold^[3], Collectin, C-type lectin-like domain, protein family^[4], C-type lectin-like domain, protein family^[5], C-type lectin, conserved site, protein family^[6]
Has part(s): C-type lectin-like domain^[7], C-type lectin, conserved site^[8], Collectin, C-type lectin-like domain^[9]
Molecular function: protein binding^[10], carbohydrate binding^[11], lipid transporter activity^[12], lipopolysaccharide binding^[13], monosaccharide binding^[14]
Cell component: extracellular region^[15], clathrin-coated endocytic vesicle^[16]

⭐ Popularity Graph

0/100 long tail

Quick Facts

Instance of protein

Part of C-type lectin-like/link domain superfamily, C-type lectin fold, Collectin, C-type lectin-like domain, protein family, C-type lectin-like domain, protein family, C-type lectin, conserved site, protein family

Properties

Biological process respiratory gaseous exchange by respiratory system, lipid transport, toll-like receptor signaling pathway, opsonization, surfactant homeostasis, positive regulation of phagocytosis, developmental process

Cell component extracellular region, clathrin-coated endocytic vesicle, collagen, lamellar granule, endoplasmic reticulum membrane, extracellular space, extracellular space, multivesicular body, rough endoplasmic reticulum

Encoded by SFTPA1

Found in taxon Homo sapiens

Has part(s) C-type lectin-like domain, C-type lectin, conserved site, Collectin, C-type lectin-like domain

Imported from wholeness_audit_2026-05-02

Molecular function protein binding, carbohydrate binding, lipid transporter activity, lipopolysaccharide binding, monosaccharide binding

Identifiers (3)

Ensembl protein id ENSP00000381633, ENSP00000397082, ENSP00000411102, ENSP00000395527

Refseq protein id NP_001087239, NP_001158116, NP_001158117, NP_001158118, NP_001158119, NP_005402, XP_005270119, XP_006718016

Uniprot protein id Q8IWL2

🏷️ Also known as

en 35 kDa pulmonary surfactant-associated protein en alveolar proteinosis protein en collectin-4 en pulmonary surfactant-associated protein A1 en SFTPA1 en SP-A1 beta en SP-A1 delta en SP-A1 epsilon en SP-A1 gamma en Surfactant protein A1 en surfactant protein A1B en surfactant protein A1 variant AB'D' 6A en surfactant protein A1 variant AB'D' 6A2 en surfactant protein A1 variant AB'D' 6A3 en surfactant protein A1 variant AB'D' 6A4 en surfactant protein A1 variant ACD' 6A en surfactant protein A1 variant ACD' 6A2 en surfactant protein A1 variant ACD' 6A3 en surfactant protein A1 variant ACD' 6A4 en surfactant protein A1 variant AD' 6A

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Surfactant protein A1 — part of (P361): C-type lectin-like/link domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[3] ↑ Surfactant protein A1 — part of (P361): C-type lectin fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[4] ↑ Surfactant protein A1 — part of (P361): Collectin, C-type lectin-like domain, protein family. wikidata.org.
[5] ↑ Surfactant protein A1 — part of (P361): C-type lectin-like domain, protein family. wikidata.org.
[6] ↑ Surfactant protein A1 — part of (P361): C-type lectin, conserved site, protein family. wikidata.org.
[7] ↑ Surfactant protein A1 — has part(s) (P527): C-type lectin-like domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Surfactant protein A1 — has part(s) (P527): C-type lectin, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Surfactant protein A1 — has part(s) (P527): Collectin, C-type lectin-like domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Surfactant protein A1 — molecular function (P680): protein binding. Glycoprotein-340 binds surfactant protein-A (SP-A) and stimulates alveolar macrophage migration in an SP-A-independent manner. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Surfactant protein A1 — molecular function (P680): carbohydrate binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Surfactant protein A1 — molecular function (P680): lipid transporter activity. Isolation and characterization of the human pulmonary surfactant apoprotein gene. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Surfactant protein A1 — molecular function (P680): lipopolysaccharide binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Surfactant protein A1 — molecular function (P680): monosaccharide binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Surfactant protein A1 — cell component (P681): extracellular region. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Surfactant protein A1 — cell component (P681): clathrin-coated endocytic vesicle. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Surfactant protein A1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Surfactant protein A1. Retrieved May 3, 2026, from https://4ort.xyz/entity/surfactant-protein-a1-q7259541

MLA

“Surfactant protein A1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/surfactant-protein-a1-q7259541.

BibTeX

@misc{4ortxyz_surfactant-protein-a1-q7259541_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Surfactant protein A1}}, year = {2026}, url = {https://4ort.xyz/entity/surfactant-protein-a1-q7259541}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Surfactant protein A1 — https://4ort.xyz/entity/surfactant-protein-a1-q7259541 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/surfactant-protein-a1-q7259541 · Last refreshed: May 3, 2026