superoxide dismutase 1

mammalian protein found in Homo sapiens

Protein protein Q2041084

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superoxide dismutase 1

Summary

superoxide dismutase 1 is a protein^[1].

Key Facts

superoxide dismutase 1's instance of is recorded as protein^[2].
superoxide dismutase 1 is part of Superoxide dismutase-like, copper/zinc binding domain superfamily^[3].
superoxide dismutase 1 is part of Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone^[4].
superoxide dismutase 1 is part of Superoxide dismutase, copper/zinc binding domain, protein family^[5].
superoxide dismutase 1 is part of Superoxide dismutase, copper/zinc, binding site, protein family^[6].
superoxide dismutase 1 comprises Superoxide dismutase, copper/zinc, binding site^[7].
superoxide dismutase 1 comprises Superoxide dismutase, copper/zinc binding domain^[8].

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Quick Facts

Instance of protein

Part of Superoxide dismutase-like, copper/zinc binding domain superfamily, Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone, Superoxide dismutase, copper/zinc binding domain, protein family, Superoxide dismutase, copper/zinc, binding site, protein family

Properties

Biological process negative regulation of neuron apoptotic process, muscle cell cellular homeostasis, response to copper ion, placenta development, response to amphetamine, positive regulation of catalytic activity, response to heat, response to organic substance, anterograde axonal transport, spermatogenesis, response to ethanol, neurofilament cytoskeleton organization, heart contraction, embryo implantation, locomotory behavior, thymus development, removal of superoxide radicals, regulation of GTPase activity, transmission of nerve impulse, response to antibiotic, myeloid cell homeostasis, response to oxidative stress, reactive oxygen species metabolic process, regulation of T cell differentiation in thymus, retina homeostasis, response to nutrient levels, hydrogen peroxide biosynthetic process, regulation of protein kinase activity, negative regulation of cholesterol biosynthetic process, cellular response to potassium ion, retrograde axonal transport, glutathione metabolic process, response to antipsychotic drug, negative regulation of apoptotic process, cellular response to cadmium ion, response to carbon monoxide, regulation of blood pressure, response to axon injury, relaxation of vascular associated smooth muscle, ovarian follicle development, cellular response to ATP, response to hydrogen peroxide, superoxide metabolic process, peripheral nervous system myelin maintenance, response to superoxide, positive regulation of cytokine production, regulation of multicellular organism growth, ageing, platelet degranulation, hearing, superoxide anion generation, auditory receptor cell stereocilium organization, regulation of mitochondrial membrane potential, positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway, positive regulation of apoptotic process, positive regulation of superoxide anion generation, regulation of organ growth, cellular iron ion homeostasis, response to reactive oxygen species, cellular response to oxidative stress, interleukin-12-mediated signaling pathway, removal of superoxide radicals, negative regulation of inflammatory response, positive regulation of phagocytosis

Cell component cytoplasm, cytosol, mitochondrial intermembrane space, extracellular region, mitochondrion, neuron projection, dendrite cytoplasm, dense core granule, nucleus, myelin sheath, peroxisome, lysosome, extracellular exosome, extracellular matrix, plasma membrane, secretory granule, nucleoplasm, soma, mitochondrial matrix, cytoplasmic vesicle, axon cytoplasm, extracellular space, extracellular space, nucleus, cytoplasm, protein-containing complex, extracellular exosome, nucleus, mitochondrion, cytosol

Ec enzyme number 1.15.1.1

Encoded by SOD1

Found in taxon Homo sapiens

Has part(s) Superoxide dismutase, copper/zinc, binding site, Superoxide dismutase, copper/zinc binding domain

Molecular function metal ion binding, enzyme binding, oxidoreductase activity, superoxide dismutase activity, protein homodimerization activity, zinc ion binding, protein binding, copper ion binding, protein phosphatase 2B binding, chaperone binding, antioxidant activity, identical protein binding, superoxide dismutase activity, copper ion binding, zinc ion binding, superoxide dismutase copper chaperone activity, superoxide dismutase activity

External References (8)

Ensembl protein id ENSP00000270142, ENSP00000374645

Freebase id /m/03cc418

Mesh descriptor id D000072105

Mesh tree code D08.811.682.881.500

Pdb structure id 1AZV, 1BA9, 1DSW, 1FUN, 1HL4, 1HL5, 1KMG, 1L3N, 1MFM, 1N18, 1N19, 1OEZ, 1OZT, 1OZU, 1P1V, 1PTZ, 1PU0, 1RK7, 1SOS, 1SPD, 1UXL, 1UXM, 2AF2, 2C9S, 2C9U, 2C9V, 2GBT, 2GBU, 2GBV, 2LU5, 2MP3, 2NNX, 2R27, 2V0A, 2VR6, 2VR7, 2VR8, 2WKO, 2WYT, 2WYZ, 2WZ0, 2WZ5, 2WZ6, 2XJK, 2XJL, 2ZKW, 2ZKX, 2ZKY, 3CQP, 3CQQ, 3ECU, 3ECV, 3ECW, 3GQF, 3GTV, 3GZO, 3GZP, 3GZQ, 3H2P, 3H2Q, 3HFF, 3K91, 3KH3, 3KH4, 3LTV, 3QQD, 3RE0, 3T5W, 4A7G, 4A7Q, 4A7S, 4A7T, 4A7U, 4A7V, 4B3E, 4BCY, 4BCZ, 4BD4, 4FF9, 4MCM, 4MCN, 4NIN, 4NIP, 4OH2, 4XCR

Refseq protein id NP_000445

Umls cui C0669516

Uniprot protein id P00441

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ superoxide dismutase 1 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ superoxide dismutase 1 — part of (P361): Superoxide dismutase-like, copper/zinc binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[4] ↑ superoxide dismutase 1 — part of (P361): Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ superoxide dismutase 1 — part of (P361): Superoxide dismutase, copper/zinc binding domain, protein family. wikidata.org.
[6] ↑ superoxide dismutase 1 — part of (P361): Superoxide dismutase, copper/zinc, binding site, protein family. wikidata.org.
[7] ↑ superoxide dismutase 1 — has part(s) (P527): Superoxide dismutase, copper/zinc, binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ superoxide dismutase 1 — has part(s) (P527): Superoxide dismutase, copper/zinc binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ superoxide dismutase 1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). superoxide dismutase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/superoxide-dismutase-1

MLA

“superoxide dismutase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/superoxide-dismutase-1.

BibTeX

@misc{4ortxyz_superoxide-dismutase-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{superoxide dismutase 1}}, year = {2026}, url = {https://4ort.xyz/entity/superoxide-dismutase-1}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): superoxide dismutase 1 — https://4ort.xyz/entity/superoxide-dismutase-1 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/superoxide-dismutase-1 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

4w ago · Boghog · 2026-07-23 view diff on Wikidata ↗

Uniprot protein id → P00441

Umls cui → C0669516

Imported from → —

Mesh descriptor id → D000072105

+ 15 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 1.15.1.1, [[:toollabs:quickstatements/#/batch/261446|batch #261446]]"

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