SRY-box transcription factor 17

mammalian protein found in Homo sapiens

Protein protein Q21108516

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SRY-box transcription factor 17

Summary

SRY-box transcription factor 17 is a protein^[1].

Key Facts

SRY-box transcription factor 17's instance of is recorded as protein^[2].
SRY-box transcription factor 17's UniProt protein ID is recorded as Q9H6I2^[3].
SRY-box transcription factor 17's part of is recorded as High mobility group box domain superfamily^[4].
SRY-box transcription factor 17's part of is recorded as Sox 7/17/18, central domain, protein family^[5].
SRY-box transcription factor 17's part of is recorded as High mobility group box domain, protein family^[6].
SRY-box transcription factor 17's part of is recorded as Sox, C-terminal domain, protein family^[7].
SRY-box transcription factor 17's has part is recorded as Sox 7/17/18, central domain^[8].
SRY-box transcription factor 17's has part is recorded as Sox, C-terminal^[9].
SRY-box transcription factor 17's has part is recorded as High mobility group box domain^[10].
SRY-box transcription factor 17's RefSeq protein ID is recorded as NP_071899^[11].
SRY-box transcription factor 17's PDB structure ID is recorded as 2YUL^[12].
SRY-box transcription factor 17's PDB structure ID is recorded as 4A3N^[13].
SRY-box transcription factor 17's molecular function is recorded as sequence-specific DNA binding^[14].
SRY-box transcription factor 17's molecular function is recorded as DNA binding^[15].
SRY-box transcription factor 17's molecular function is recorded as beta-catenin binding^[16].
SRY-box transcription factor 17's molecular function is recorded as DNA-binding transcription factor activity^[17].
SRY-box transcription factor 17's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[18].
SRY-box transcription factor 17's molecular function is recorded as transcription coactivator activity^[19].
SRY-box transcription factor 17's molecular function is recorded as transcription factor binding^[20].
SRY-box transcription factor 17's molecular function is recorded as protein binding^[21].
SRY-box transcription factor 17's molecular function is recorded as protein heterodimerization activity^[22].
SRY-box transcription factor 17's molecular function is recorded as transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding^[23].
SRY-box transcription factor 17's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[24].
SRY-box transcription factor 17's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific^[25].
SRY-box transcription factor 17's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[26].

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Quick Facts

Instance of protein

Part of High mobility group box domain superfamily, Sox 7/17/18, central domain, protein family, High mobility group box domain, protein family, Sox, C-terminal domain, protein family

Properties

Biological process renal system development, endoderm development, regulation of embryonic development, regulation of transcription, DNA-templated, positive regulation of protein catabolic process, stem cell fate specification, positive regulation of skeletal muscle tissue development, embryonic foregut morphogenesis, embryonic organ development, endodermal digestive tract morphogenesis, negative regulation of mesodermal cell fate specification, inner cell mass cellular morphogenesis, negative regulation of Wnt signaling pathway, protein stabilization, endocardium formation, outflow tract morphogenesis, signal transduction involved in regulation of gene expression, endodermal cell fate determination, mRNA transcription by RNA polymerase II, regulation of mesodermal cell fate specification, negative regulation of transcription by RNA polymerase II, Wnt signaling pathway, endocardial cell differentiation, regulation of cardiac cell fate specification, transcription, DNA-templated, stem cell differentiation, embryonic heart tube development, vasculogenesis, positive regulation of transcription, DNA-templated, heart looping, cardiac cell fate determination, common bile duct development, negative regulation of Wnt signaling pathway involved in heart development, rostrocaudal neural tube patterning, positive regulation of gene expression, cardiogenic plate morphogenesis, heart formation, embryonic heart tube morphogenesis, negative regulation of cell growth, protein destabilization, angiogenesis, spermatogenesis, positive regulation of cell differentiation, regulation of stem cell division, gastrulation, gall bladder development, canonical Wnt signaling pathway, regulation of cell differentiation, cell migration involved in gastrulation, endoderm formation, regulation of stem cell proliferation, negative regulation of canonical Wnt signaling pathway, positive regulation of transcription by RNA polymerase II, cellular response to leukemia inhibitory factor, negative regulation of canonical Wnt signaling pathway, negative regulation of transcription by RNA polymerase II, angiogenesis, vasculogenesis, regulation of transcription, DNA-templated, cell differentiation, positive regulation of transcription by RNA polymerase II

Cell component transcription regulator complex, nucleoplasm, nucleus, nucleus

Encoded by SOX17

Found in taxon Homo sapiens

Has part(s) Sox 7/17/18, central domain, Sox, C-terminal, High mobility group box domain

Imported from wholeness_audit_2026-05-02

Molecular function sequence-specific DNA binding, DNA binding, beta-catenin binding, DNA-binding transcription factor activity, DNA-binding transcription activator activity, RNA polymerase II-specific, transcription coactivator activity, transcription factor binding, protein binding, protein heterodimerization activity, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific

External References (4)

Ensembl protein id ENSP00000297316

Pdb structure id 2YUL, 4A3N

Refseq protein id NP_071899

Uniprot protein id Q9H6I2

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ SRY-box transcription factor 17 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ SRY-box transcription factor 17 — UniProt protein ID (P352): Q9H6I2. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ SRY-box transcription factor 17 — part of (P361): High mobility group box domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ SRY-box transcription factor 17 — part of (P361): Sox 7/17/18, central domain, protein family. wikidata.org.
[6] ↑ SRY-box transcription factor 17 — part of (P361): High mobility group box domain, protein family. wikidata.org.
[7] ↑ SRY-box transcription factor 17 — part of (P361): Sox, C-terminal domain, protein family. wikidata.org.
[8] ↑ SRY-box transcription factor 17 — has part(s) (P527): Sox 7/17/18, central domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ SRY-box transcription factor 17 — has part(s) (P527): Sox, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ SRY-box transcription factor 17 — has part(s) (P527): High mobility group box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ SRY-box transcription factor 17 — RefSeq protein ID (P637): NP_071899. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ SRY-box transcription factor 17 — PDB structure ID (P638): 2YUL. Q905695. Retrieved 2016-03-21. wikidata.org.
[13] ↑ SRY-box transcription factor 17 — PDB structure ID (P638): 4A3N. Q905695. Retrieved 2016-03-21. wikidata.org.
[14] ↑ SRY-box transcription factor 17 — molecular function (P680): sequence-specific DNA binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ SRY-box transcription factor 17 — molecular function (P680): DNA binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ SRY-box transcription factor 17 — molecular function (P680): beta-catenin binding. Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ SRY-box transcription factor 17 — molecular function (P680): DNA-binding transcription factor activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ SRY-box transcription factor 17 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2018-07-16. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ SRY-box transcription factor 17 — molecular function (P680): transcription coactivator activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ SRY-box transcription factor 17 — molecular function (P680): transcription factor binding. Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ SRY-box transcription factor 17 — molecular function (P680): protein binding. Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ SRY-box transcription factor 17 — molecular function (P680): protein heterodimerization activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ SRY-box transcription factor 17 — molecular function (P680): transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ SRY-box transcription factor 17 — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. A census of human transcription factors: function, expression and evolution. Retrieved 2018-07-16. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ SRY-box transcription factor 17 — molecular function (P680): DNA-binding transcription factor activity, RNA polymerase II-specific. A census of human transcription factors: function, expression and evolution. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ SRY-box transcription factor 17 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ SRY-box transcription factor 17 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

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BibTeX

@misc{4ortxyz_sry-box-transcription-factor-17-q21108516_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{SRY-box transcription factor 17}}, year = {2026}, url = {https://4ort.xyz/entity/sry-box-transcription-factor-17-q21108516}, note = {Accessed: 2026-05-03}}

LLM prompt

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