Sphingosine kinase 1
mammalian protein found in Homo sapiens
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Summary
Sphingosine kinase 1 is a protein[1]. It is known by 6 alternative names across languages and contexts.[2]
Key Facts
- Part of: Inorganic polyphosphate/ATP-NAD kinase, N-terminal[3], NAD kinase/diacylglycerol kinase-like domain superfamily[4], Diacylglycerol kinase, catalytic domain, protein family[5]
- Has part(s): Diacylglycerol kinase, catalytic domain[6]
- Molecular function: sphingosine-1-phosphate receptor activity[7], transferase activity[8], nucleotide binding[9], DNA binding[10], calmodulin binding[11], kinase activity[12], protein binding[13], protein phosphatase 2A binding[14], ATP binding[15], magnesium ion binding[16], sphinganine kinase activity[17], D-erythro-sphingosine kinase activity[18], NAD+ kinase activity[19], lipid binding[20]
- Cell component: cytoplasm[21], membrane[22], plasma membrane[23], nucleus[24], cytosol[25], clathrin-coated pit[26], endocytic vesicle[27], early endosome membrane[28], presynapse[29], endosome[30], endosome membrane[31], cell junction[32], synapse[33]
- Biological process: intracellular signal transduction[34], positive regulation of fibroblast proliferation[35], sphingosine metabolic process[36], regulation of tumor necrosis factor-mediated signaling pathway[37], sphingosine biosynthetic process[38], positive regulation of mitotic cell cycle[39], sphingolipid biosynthetic process[40], positive regulation of angiogenesis[41], positive regulation of cell growth[42], brain development[43], blood vessel development[44], positive regulation of NF-kappaB transcription factor activity[45], positive regulation of peptidyl-threonine phosphorylation[46], protein folding[47]