SPG7 matrix AAA peptidase subunit, paraplegin

mammalian protein found in Homo sapiens

Protein protein Q7135735

Press Enter · cited answer in seconds

Summary

SPG7 matrix AAA peptidase subunit, paraplegin is a protein^[1].

Key Facts

SPG7 matrix AAA peptidase subunit, paraplegin's instance of is recorded as protein^[2].
SPG7 matrix AAA peptidase subunit, paraplegin's UniProt protein ID is recorded as Q9UQ90^[3].
SPG7 matrix AAA peptidase subunit, paraplegin's part of is recorded as Peptidase, FtsH^[4].
SPG7 matrix AAA peptidase subunit, paraplegin's part of is recorded as Peptidase M41-like^[5].
SPG7 matrix AAA peptidase subunit, paraplegin's part of is recorded as P-loop containing nucleoside triphosphate hydrolase^[6].
SPG7 matrix AAA peptidase subunit, paraplegin's part of is recorded as ATPase, AAA-type, core domain, protein family^[7].
SPG7 matrix AAA peptidase subunit, paraplegin's part of is recorded as AAA proteins^[8].
SPG7 matrix AAA peptidase subunit, paraplegin's part of is recorded as Peptidase M41 family^[9].
SPG7 matrix AAA peptidase subunit, paraplegin's part of is recorded as Peptidase M41, FtsH extracellular domain, protein family^[10].
SPG7 matrix AAA peptidase subunit, paraplegin's has part is recorded as Peptidase M41, FtsH extracellular^[11].
SPG7 matrix AAA peptidase subunit, paraplegin's has part is recorded as Peptidase M41^[12].
SPG7 matrix AAA peptidase subunit, paraplegin's has part is recorded as AAA+ ATPase domain^[13].
SPG7 matrix AAA peptidase subunit, paraplegin's has part is recorded as ATPase, AAA-type, core^[14].
SPG7 matrix AAA peptidase subunit, paraplegin's RefSeq protein ID is recorded as NP_003110^[15].
SPG7 matrix AAA peptidase subunit, paraplegin's RefSeq protein ID is recorded as NP_955399^[16].
SPG7 matrix AAA peptidase subunit, paraplegin's RefSeq protein ID is recorded as XP_005256378^[17].
SPG7 matrix AAA peptidase subunit, paraplegin's RefSeq protein ID is recorded as XP_016879086^[18].
SPG7 matrix AAA peptidase subunit, paraplegin's RefSeq protein ID is recorded as XP_016879087^[19].
SPG7 matrix AAA peptidase subunit, paraplegin's RefSeq protein ID is recorded as NP_001350779^[20].
SPG7 matrix AAA peptidase subunit, paraplegin's PDB structure ID is recorded as 2QZ4^[21].
SPG7 matrix AAA peptidase subunit, paraplegin's molecular function is recorded as unfolded protein binding^[22].
SPG7 matrix AAA peptidase subunit, paraplegin's molecular function is recorded as nucleotide binding^[23].
SPG7 matrix AAA peptidase subunit, paraplegin's molecular function is recorded as peptidase activity^[24].
SPG7 matrix AAA peptidase subunit, paraplegin's molecular function is recorded as zinc ion binding^[25].
SPG7 matrix AAA peptidase subunit, paraplegin's molecular function is recorded as metalloendopeptidase activity^[26].

⭐ Popularity Graph

0/100 long tail

Quick Facts

Instance of protein

Part of Peptidase, FtsH, Peptidase M41-like, P-loop containing nucleoside triphosphate hydrolase, ATPase, AAA-type, core domain, protein family, AAA proteins, Peptidase M41 family, Peptidase M41, FtsH extracellular domain, protein family

Properties

Biological process proteolysis, nervous system development, mitochondrial calcium ion transmembrane transport, regulation of mitochondrial membrane permeability, mitochondrial outer membrane permeabilization involved in programmed cell death, mitochondrion organization, anterograde axonal transport, regulation of mitochondrial membrane permeability, mitochondrial outer membrane permeabilization involved in programmed cell death

Cell component integral component of membrane, mitochondrion, membrane, mitochondrial inner membrane, mitochondrial permeability transition pore complex, mitochondrion, m-AAA complex, axon cytoplasm

Encoded by SPG7

Found in taxon Homo sapiens

Has part(s) Peptidase M41, FtsH extracellular, Peptidase M41, AAA+ ATPase domain, ATPase, AAA-type, core

Imported from wholeness_audit_2026-05-02

Molecular function unfolded protein binding, nucleotide binding, peptidase activity, zinc ion binding, metalloendopeptidase activity, protein binding, hydrolase activity, ATP binding, metallopeptidase activity, metal ion binding

External References (4)

Ensembl protein id ENSP00000268704, ENSP00000341157, ENSP00000454475, ENSP00000454805, ENSP00000457298, ENSP00000457387, ENSP00000461979, ENSP00000483351, ENSP00000495734, ENSP00000494160, ENSP00000495673, ENSP00000496403, ENSP00000496434, ENSP00000493934, ENSP00000495219, ENSP00000493908, ENSP00000494895, ENSP00000493826, ENSP00000495123, ENSP00000495783, ENSP00000495967, ENSP00000494000, ENSP00000494903, ENSP00000496510, ENSP00000494158, ENSP00000494119, ENSP00000495690, ENSP00000496047, ENSP00000496244, ENSP00000494111, ENSP00000496335, ENSP00000495185, ENSP00000495260, ENSP00000493590, ENSP00000493797, ENSP00000495795, ENSP00000494806, ENSP00000494739, ENSP00000494246, ENSP00000495297, ENSP00000495293, ENSP00000493982, ENSP00000495352, ENSP00000495675, ENSP00000495473, ENSP00000495004, ENSP00000495593, ENSP00000495999

Pdb structure id 2QZ4

Refseq protein id NP_003110, NP_955399, XP_005256378, XP_016879086, XP_016879087, NP_001350779

Uniprot protein id Q9UQ90

🏷️ Also known as

en cell matrix adhesion regulator en paraplegin en spastic paraplegia 7 protein en spastic paraplegia 7 (pure and complicated autosomal recessive) en SPG7 en SPG7 matrix AAA peptidase subunit, paraplegin en SPG7, paraplegin matrix AAA peptidase subunit

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — instance of (P31): protein. UniProt. Retrieved 2019-11-13. wikidata.org.
[3] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — UniProt protein ID (P352): Q9UQ90. UniProt. Retrieved 2019-11-13. wikidata.org.
[4] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — part of (P361): Peptidase, FtsH. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — part of (P361): Peptidase M41-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — part of (P361): ATPase, AAA-type, core domain, protein family. wikidata.org.
[8] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — part of (P361): AAA proteins. wikidata.org.
[9] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — part of (P361): Peptidase M41 family. wikidata.org.
[10] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — part of (P361): Peptidase M41, FtsH extracellular domain, protein family. wikidata.org.
[11] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — has part(s) (P527): Peptidase M41, FtsH extracellular. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — has part(s) (P527): Peptidase M41. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — has part(s) (P527): AAA+ ATPase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — has part(s) (P527): ATPase, AAA-type, core. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — RefSeq protein ID (P637): NP_003110. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — RefSeq protein ID (P637): NP_955399. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — RefSeq protein ID (P637): XP_005256378. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — RefSeq protein ID (P637): XP_016879086. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — RefSeq protein ID (P637): XP_016879087. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — RefSeq protein ID (P637): NP_001350779. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — PDB structure ID (P638): 2QZ4. UniProt. Retrieved 2016-08-09. wikidata.org.
[22] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — molecular function (P680): unfolded protein binding. Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — molecular function (P680): peptidase activity. Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — molecular function (P680): zinc ion binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ SPG7 matrix AAA peptidase subunit, paraplegin — molecular function (P680): metalloendopeptidase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ SPG7 matrix AAA peptidase subunit, paraplegin is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). SPG7 matrix AAA peptidase subunit, paraplegin. Retrieved May 3, 2026, from https://4ort.xyz/entity/spg7-matrix-aaa-peptidase-subunit-paraplegin

MLA

“SPG7 matrix AAA peptidase subunit, paraplegin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/spg7-matrix-aaa-peptidase-subunit-paraplegin.

BibTeX

@misc{4ortxyz_spg7-matrix-aaa-peptidase-subunit-paraplegin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{SPG7 matrix AAA peptidase subunit, paraplegin}}, year = {2026}, url = {https://4ort.xyz/entity/spg7-matrix-aaa-peptidase-subunit-paraplegin}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): SPG7 matrix AAA peptidase subunit, paraplegin — https://4ort.xyz/entity/spg7-matrix-aaa-peptidase-subunit-paraplegin (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/spg7-matrix-aaa-peptidase-subunit-paraplegin · Last refreshed: May 3, 2026