Sortilin-related receptor, LDLR class A repeats-containing

mammalian protein found in Mus musculus

Protein protein Q21988145

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Sortilin-related receptor, LDLR class A repeats-containing

Summary

Sortilin-related receptor, LDLR class A repeats-containing is a protein^[1].

Key Facts

Sortilin-related receptor, LDLR class A repeats-containing's instance of is recorded as protein^[2].
Sortilin-related receptor, LDLR class A repeats-containing's UniProt protein ID is recorded as O88307^[3].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as Fibronectin type III superfamily^[4].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as Immunoglobulin-like fold^[5].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as LDL receptor-like superfamily^[6].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as Six-bladed beta-propeller, TolB-like^[7].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as WD40/YVTN repeat-like-containing domain superfamily^[8].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as membrane protein^[9].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as VPS10, protein family^[10].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as Sortilin, C-terminal domain, protein family^[11].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as Fibronectin type III, protein family^[12].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as Sortilin, N-terminal domain, protein family^[13].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as Low-density lipoprotein (LDL) receptor class A, conserved site, protein family^[14].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as Low-density lipoprotein (LDL) receptor class A repeat, protein family^[15].
Sortilin-related receptor, LDLR class A repeats-containing's part of is recorded as LDLR class B repeat, protein family^[16].
Sortilin-related receptor, LDLR class A repeats-containing's has part is recorded as Sortilin, N-terminal^[17].
Sortilin-related receptor, LDLR class A repeats-containing's has part is recorded as fibronectin type III^[18].
Sortilin-related receptor, LDLR class A repeats-containing's has part is recorded as Sortilin, C-terminal^[19].
Sortilin-related receptor, LDLR class A repeats-containing's has part is recorded as low-density lipoprotein (LDL) receptor class A repeat^[20].
Sortilin-related receptor, LDLR class A repeats-containing's has part is recorded as LDLR class B repeat^[21].
Sortilin-related receptor, LDLR class A repeats-containing's has part is recorded as VPS10^[22].
Sortilin-related receptor, LDLR class A repeats-containing's has part is recorded as Low-density lipoprotein (LDL) receptor class A, conserved site^[23].
Sortilin-related receptor, LDLR class A repeats-containing's RefSeq protein ID is recorded as NP_035566^[24].
Sortilin-related receptor, LDLR class A repeats-containing's RefSeq protein ID is recorded as NP_001344190^[25].
Sortilin-related receptor, LDLR class A repeats-containing's molecular function is recorded as amyloid-beta binding^[26].

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Quick Facts

Instance of protein

Part of Fibronectin type III superfamily, Immunoglobulin-like fold, LDL receptor-like superfamily, Six-bladed beta-propeller, TolB-like, WD40/YVTN repeat-like-containing domain superfamily, membrane protein, VPS10, protein family, Sortilin, C-terminal domain, protein family, Fibronectin type III, protein family, Sortilin, N-terminal domain, protein family, Low-density lipoprotein (LDL) receptor class A, conserved site, protein family, Low-density lipoprotein (LDL) receptor class A repeat, protein family, LDLR class B repeat, protein family

Properties

Biological process negative regulation of tau-protein kinase activity, protein targeting, steroid metabolic process, positive regulation of choline O-acetyltransferase activity, lipid transport, protein targeting to lysosome, negative regulation of neurofibrillary tangle assembly, endocytosis, positive regulation of protein catabolic process, lipid metabolism, negative regulation of amyloid-beta formation, negative regulation of protein oligomerization, negative regulation of neurogenesis, protein maturation, negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process, cholesterol metabolic process, negative regulation of protein binding, positive regulation of ER to Golgi vesicle-mediated transport, positive regulation of early endosome to recycling endosome transport, post-Golgi vesicle-mediated transport, multicellular organism development, negative regulation of MAP kinase activity, regulation of smooth muscle cell migration, positive regulation of protein localization to early endosome, positive regulation of endocytic recycling, negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process, positive regulation of protein exit from endoplasmic reticulum, protein retention in Golgi apparatus, negative regulation of neuron death, protein localization to Golgi apparatus, cell migration, protein targeting to lysosome, post-Golgi vesicle-mediated transport, protein retention in Golgi apparatus

Cell component integral component of membrane, recycling endosome, endosome, Golgi apparatus, membrane, Golgi cisterna, extracellular region, trans-Golgi network, early endosome, endoplasmic reticulum, low-density lipoprotein particle, nuclear envelope lumen, perinuclear region of cytoplasm, extracellular space, multivesicular body, soma, Golgi apparatus, integral component of membrane

Encoded by Sorl1

Found in taxon house mouse

Has part(s) Sortilin, N-terminal, fibronectin type III, Sortilin, C-terminal, low-density lipoprotein (LDL) receptor class A repeat, LDLR class B repeat, VPS10, Low-density lipoprotein (LDL) receptor class A, conserved site

Imported from wholeness_audit_2026-05-02

Molecular function amyloid-beta binding, low-density lipoprotein particle binding, protein binding

External References (3)

Ensembl protein id ENSMUSP00000058613

Refseq protein id NP_035566, NP_001344190

Uniprot protein id O88307

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Sortilin-related receptor, LDLR class A repeats-containing — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Sortilin-related receptor, LDLR class A repeats-containing — UniProt protein ID (P352): O88307. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): Fibronectin type III superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): Immunoglobulin-like fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): LDL receptor-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): Six-bladed beta-propeller, TolB-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): WD40/YVTN repeat-like-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): membrane protein. wikidata.org.
[10] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): VPS10, protein family. wikidata.org.
[11] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): Sortilin, C-terminal domain, protein family. wikidata.org.
[12] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): Fibronectin type III, protein family. wikidata.org.
[13] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): Sortilin, N-terminal domain, protein family. wikidata.org.
[14] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): Low-density lipoprotein (LDL) receptor class A, conserved site, protein family. wikidata.org.
[15] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): Low-density lipoprotein (LDL) receptor class A repeat, protein family. wikidata.org.
[16] ↑ Sortilin-related receptor, LDLR class A repeats-containing — part of (P361): LDLR class B repeat, protein family. wikidata.org.
[17] ↑ Sortilin-related receptor, LDLR class A repeats-containing — has part(s) (P527): Sortilin, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Sortilin-related receptor, LDLR class A repeats-containing — has part(s) (P527): fibronectin type III. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Sortilin-related receptor, LDLR class A repeats-containing — has part(s) (P527): Sortilin, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Sortilin-related receptor, LDLR class A repeats-containing — has part(s) (P527): low-density lipoprotein (LDL) receptor class A repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Sortilin-related receptor, LDLR class A repeats-containing — has part(s) (P527): LDLR class B repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Sortilin-related receptor, LDLR class A repeats-containing — has part(s) (P527): VPS10. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Sortilin-related receptor, LDLR class A repeats-containing — has part(s) (P527): Low-density lipoprotein (LDL) receptor class A, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Sortilin-related receptor, LDLR class A repeats-containing — RefSeq protein ID (P637): NP_035566. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Sortilin-related receptor, LDLR class A repeats-containing — RefSeq protein ID (P637): NP_001344190. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Sortilin-related receptor, LDLR class A repeats-containing — molecular function (P680): amyloid-beta binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Sortilin-related receptor, LDLR class A repeats-containing is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Sortilin-related receptor, LDLR class A repeats-containing. Retrieved May 3, 2026, from https://4ort.xyz/entity/sortilin-related-receptor-ldlr-class-a-repeats-containing

MLA

“Sortilin-related receptor, LDLR class A repeats-containing.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/sortilin-related-receptor-ldlr-class-a-repeats-containing.

BibTeX

@misc{4ortxyz_sortilin-related-receptor-ldlr-class-a-repeats-containing_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Sortilin-related receptor, LDLR class A repeats-containing}}, year = {2026}, url = {https://4ort.xyz/entity/sortilin-related-receptor-ldlr-class-a-repeats-containing}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Sortilin-related receptor, LDLR class A repeats-containing — https://4ort.xyz/entity/sortilin-related-receptor-ldlr-class-a-repeats-containing (retrieved 2026-05-03)

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