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SKI proto-oncogene

mammalian protein found in Homo sapiens
Protein protein Q14913250
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SKI proto-oncogene

Summary

SKI proto-oncogene is a protein[1].

Key Facts

  • SKI proto-oncogene's instance of is recorded as protein[2].
  • SKI proto-oncogene's UniProt protein ID is recorded as P12755[3].
  • SKI proto-oncogene's part of is recorded as SAND-like domain superfamily[4].
  • SKI proto-oncogene's part of is recorded as Ski oncogene[5].
  • SKI proto-oncogene's part of is recorded as Putative DNA-binding domain superfamily[6].
  • SKI proto-oncogene's part of is recorded as Ski-like, DNA-binding domain superfamily[7].
  • SKI proto-oncogene's part of is recorded as SKI/SNO/DAC domain, protein family[8].
  • SKI proto-oncogene's part of is recorded as c-SKI SMAD4-binding domain, protein family[9].
  • SKI proto-oncogene's has part is recorded as c-SKI SMAD4-binding domain[10].
  • SKI proto-oncogene's has part is recorded as SKI/SNO/DAC domain[11].
  • SKI proto-oncogene's RefSeq protein ID is recorded as NP_003027[12].
  • SKI proto-oncogene's RefSeq protein ID is recorded as XP_005244832[13].
  • SKI proto-oncogene's RefSeq protein ID is recorded as XP_005244833[14].
  • SKI proto-oncogene's RefSeq protein ID is recorded as XP_016857617[15].
  • SKI proto-oncogene's PDB structure ID is recorded as 1MR1[16].
  • SKI proto-oncogene's PDB structure ID is recorded as 1SBX[17].
  • SKI proto-oncogene's molecular function is recorded as transcription corepressor activity[18].
  • SKI proto-oncogene's molecular function is recorded as protein domain specific binding[19].
  • SKI proto-oncogene's molecular function is recorded as histone deacetylase inhibitor activity[20].
  • SKI proto-oncogene's molecular function is recorded as zinc ion binding[21].
  • SKI proto-oncogene's molecular function is recorded as protein binding[22].
  • SKI proto-oncogene's molecular function is recorded as SMAD binding[23].
  • SKI proto-oncogene's molecular function is recorded as protein kinase binding[24].
  • SKI proto-oncogene's molecular function is recorded as ubiquitin protein ligase binding[25].
  • SKI proto-oncogene's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . Q905695. Retrieved . wikidata.org.
  2. [3] ↑ . Q905695. Retrieved . wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . wikidata.org.
  8. [9] ↑ . wikidata.org.
  9. [10] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . Q20641742. Retrieved . wikidata.org.
  12. [13] ↑ . Q20641742. Retrieved . wikidata.org.
  13. [14] ↑ . Q20641742. Retrieved . wikidata.org.
  14. [15] ↑ . Q20641742. Retrieved . wikidata.org.
  15. [16] ↑ . Q905695. Retrieved . wikidata.org.
  16. [17] ↑ . Q905695. Retrieved . wikidata.org.
  17. [18] ↑ . Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . The Ski protein family is required for MeCP2-mediated transcriptional repression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] ↑ . Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] ↑ . Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] ↑ . A census of human transcription factors: function, expression and evolution. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). SKI proto-oncogene. Retrieved May 3, 2026, from https://4ort.xyz/entity/ski-proto-oncogene
MLA “SKI proto-oncogene.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ski-proto-oncogene.
BibTeX @misc{4ortxyz_ski-proto-oncogene_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{SKI proto-oncogene}}, year = {2026}, url = {https://4ort.xyz/entity/ski-proto-oncogene}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): SKI proto-oncogene — https://4ort.xyz/entity/ski-proto-oncogene (retrieved 2026-05-03)

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