Signal peptide peptidase like 3

mammalian protein found in Homo sapiens
Protein protein Q21122091
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Summary

Signal peptide peptidase like 3 is a protein[1].

Key Facts

  • Signal peptide peptidase like 3's instance of is recorded as protein[2].
  • Signal peptide peptidase like 3's UniProt protein ID is recorded as Q8TCT6[3].
  • Signal peptide peptidase like 3's part of is recorded as Peptidase A22B, signal peptide peptidase[4].
  • Signal peptide peptidase like 3's RefSeq protein ID is recorded as NP_620584[5].
  • Signal peptide peptidase like 3's RefSeq protein ID is recorded as XP_011536227[6].
  • Signal peptide peptidase like 3's molecular function is recorded as protein homodimerization activity[7].
  • Signal peptide peptidase like 3's molecular function is recorded as aspartic-type endopeptidase activity[8].
  • Signal peptide peptidase like 3's molecular function is recorded as aspartic endopeptidase activity, intramembrane cleaving[9].
  • Signal peptide peptidase like 3's molecular function is recorded as peptidase activity[10].
  • Signal peptide peptidase like 3's molecular function is recorded as protein binding[11].
  • Signal peptide peptidase like 3's molecular function is recorded as hydrolase activity[12].
  • Signal peptide peptidase like 3's molecular function is recorded as aspartic endopeptidase activity, intramembrane cleaving[13].
  • Signal peptide peptidase like 3's cell component is recorded as integral component of membrane[14].
  • Signal peptide peptidase like 3's cell component is recorded as rough endoplasmic reticulum[15].
  • Signal peptide peptidase like 3's cell component is recorded as Golgi apparatus[16].
  • Signal peptide peptidase like 3's cell component is recorded as endoplasmic reticulum membrane[17].
  • Signal peptide peptidase like 3's cell component is recorded as membrane[18].
  • Signal peptide peptidase like 3's cell component is recorded as intracellular membrane-bounded organelle[19].
  • Signal peptide peptidase like 3's cell component is recorded as integral component of cytoplasmic side of endoplasmic reticulum membrane[20].
  • Signal peptide peptidase like 3's cell component is recorded as plasma membrane[21].
  • Signal peptide peptidase like 3's cell component is recorded as endoplasmic reticulum[22].
  • Signal peptide peptidase like 3's cell component is recorded as Golgi-associated vesicle membrane[23].
  • Signal peptide peptidase like 3's cell component is recorded as integral component of lumenal side of endoplasmic reticulum membrane[24].
  • Signal peptide peptidase like 3's cell component is recorded as endoplasmic reticulum-Golgi intermediate compartment membrane[25].
  • Signal peptide peptidase like 3's cell component is recorded as lysosomal membrane[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . UniProt. Retrieved . wikidata.org.
  2. [3] ↑ . UniProt. Retrieved . wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . Q20641742. Retrieved . wikidata.org.
  5. [6] ↑ . Q20641742. Retrieved . wikidata.org.
  6. [7] ↑ . Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . In vivo measurements of ethanol concentration in rabbit brain by 1H magnetic resonance spectroscopy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] ↑ . Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Signal peptide peptidase like 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/signal-peptide-peptidase-like-3
MLA “Signal peptide peptidase like 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/signal-peptide-peptidase-like-3.
BibTeX @misc{4ortxyz_signal-peptide-peptidase-like-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Signal peptide peptidase like 3}}, year = {2026}, url = {https://4ort.xyz/entity/signal-peptide-peptidase-like-3}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Signal peptide peptidase like 3 — https://4ort.xyz/entity/signal-peptide-peptidase-like-3 (retrieved 2026-05-03)

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